Results 171 to 180 of about 724,472 (302)
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
The HEAT Repeat Protein MROH1 Deficiency Leads to Reduced Circulating Thyroid Hormone Levels in Mice. [PDF]
Ohuchi N +12 more
europepmc +1 more source
Dietary UV filter EHMC induces hepatic steatosis in HepaRG cells at noncytotoxic concentrations. Mechanistically, EHMC binds nuclear receptors (LXRα, PPARα), upregulating SREBP‐1 to accelerate fatty acid synthesis. These findings highlight the potential metabolic toxicity of widespread EHMC exposure through food sources.
Shanglin Yang +3 more
wiley +1 more source
A thyroid hormone-mediated opsin switch initiates metamorphosis in a proto-vertebrate. [PDF]
Mariossi A, Levine MS.
europepmc +1 more source
Potential of Seaweed to Improve the Quality and Shelf Life of Fish and Fishery Products
Growing global demand for safe fish preservation has increased interest in natural alternatives. Seaweed‐derived bioactive compounds possess antioxidant and antimicrobial properties that enhance fish quality, safety, and shelf life. These sustainable preservatives may reduce spoilage and synthetic preservative use, though further research ...
Ashika Banu Rodela +5 more
wiley +1 more source
Beyond Hormone Levels: Thyroid Hormone Signaling from Neurogenesis to Alzheimer's Disease. [PDF]
Del Seppia C, Sabatino L.
europepmc +1 more source
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell +11 more
wiley +1 more source
Thyroid hormone replacement is associated with improvement in renal dysfunction in patients with hypothyroidism: a retrospective observational study. [PDF]
Zhao T, Zhang N, Tian Y, Yang Z.
europepmc +1 more source
ABSTRACT Background Intraoperative neuromonitoring (IONM) is a reliable tool to detect electromyographic loss of signal (LOS). Here, we investigated the effect of electromyography features of traction‐related LOS on prognosis. Methods Thyroidectomy patients with a traction‐related LOS were included.
Serkan Karaisli +3 more
wiley +1 more source

