Results 121 to 130 of about 583,270 (252)

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Study of 99mTc Pertechnetate Radiopharmaceuticals in Relation to Thyroid Hormone for Toxic and non-Toxic Diffuse Goiter

Atom Indonesia, 2012
Abnormalities of the thyroid gland in the form of enlargement of the thyroid gland are called a goiter. Goiter is divided into two types, namely toxic and non-toxic diffuse goiter.
N.P. Viantri , W. Setiabudi , C. Anam, F. Nadzir, C. Varuna   +4 more
doaj  

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Investigating factors associated with thyroid hormone measurements during pregnancy

European Thyroid Journal
Background: Accurate assessment of thyroid status is essential for maternal and fetal management during pregnancy. This study measured human chorionic gonadotropin (HCG), albumin, and thyroxine-binding globulin (TBG) levels during pregnancy to clarify ...
Miho Fukushita, Jaeduk Yoshimura Noh, Natsuko Watanabe, Kosuke Inoue, Ai Yoshihara, Masako Matsumoto, Nami Suzuki, Masahiro Ichikawa, Masakazu Koshibu, Rei Hirose, Tatsuya Iida, Toshino Suzuki, Kiminori Sugino, Koichi Ito   +13 more
doaj   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Lithium‐related adverse drug reactions in children: A case–control study comparing lithium to second‐generation antipsychotics in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to improve the understanding of lithium's safety profile by analysing the frequency and distribution of reported adverse drug reactions (ADRs) compared to second‐generation antipsychotics (SGAs). Methods Individual case safety reports from VigiBase (1968–October 2023) involving individuals older than 2 years, with lithium or SGAs ...
Lisa T. Ringeling, Ravish N. Gangapersad, Lillian Lieuw, Patrick C. Souverein, Eibert R. Heerdink, Pilar Garcia‐Gomez, Manon H. J. Hillegers, Birgit C. P. Koch, Bram Dierckx   +8 more
wiley   +1 more source

Thyroid Hormones [PDF]

BMJ, 1959
openaire   +2 more sources

Association of impaired sensitivity to thyroid hormone with low bone mineral density and bone mineral content

Frontiers in Endocrinology
Osteoporosis is a systemic condition characterized by reduced bone mineral density (BMD) and bone mineral content (BMC), with its global prevalence increasing annually.
Guoning Meng, Yuxian Bing, Yulin Liu, Zufei Zhou, Yuanmeng Li, Yichen Han, Yaqiu Jiang, Yaqiu Jiang   +7 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Thyroid Dysfunction Secondary to Endocrine Disruptive Chemicals – A Systematic Review

Pakistan Armed Forces Medical Journal
Objectives: To assess the epidemiological data and potential connection between different endocrine chemical disruptors and thyroid hormone abnormalities. Study Design: The 2020 PRISMA standards were followed when conducting the systematic review. Ten
Ambreen Gul, Sarah Saleem, Faizan Munir, Aashi Ahmed, Anwar Bibi, Sadia Naeem   +5 more
doaj   +1 more source