Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]
, 2002 Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Assink, Y. +7 more
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The Syndromes of Resistance to Thyroid Hormone Beta
罕见病研究, 2023 The syndrome of resistance to thyroid hormone(RTH) is a rare syndrome caused by the mutation of thyroid hormone receptor (TR) gene, which reduces the sensitivity of target organs to thyroid hormone (TH) and leads to the dysfunction of TH. Thyroid hormone
WANG Huangman +2 more
doaj +1 more source
Folia Endocrinologica Japonica, 1993 Most thyroxine (T4) secreted from the thyroid is deiodinated in peripheral tissues. At least three isozymes are known in iodothyronine deiodinase which catalyzes the conversion of T4 to triiodothyronine (T3) or reverse T3. Type I 5'-deiodinase (5'D-I) exists in most tissues including the liver, kidney and thyroid.
M, Inada, M, Nishikawa
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Thyroid hormone receptors and ligand, tissue distribution and sexual behavior [PDF]
, 2018 The thyroid hormones (THs) triiodothyronine (T3) and tetraiodothyronine, or thyroxine (T4), not only dramatically impact on development and differentiation, but also on the sexual and reproductive function.
Carosa, E, Jannini, Ea, Lenzi, A
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Thyroid hormone upregulates zinc-α2-glycoprotein production in the liver but not in adipose tissue. [PDF]
PLoS ONE, 2014 Overproduction of zinc-α2-glycoprotein by adipose tissue is crucial in accounting for the lipolysis occurring in cancer cachexia of certain malignant tumors.
Rafael Simó +5 more
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Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis [PDF]
, 2014 We have shown in vitro that thyroid hormones (THs) regulate the balance between proliferation and apoptosis of T lymphoma cells. The effects of THs on tumor development have been studied, but the results are still controversial.
Barreiro Arcos, María Laura +10 more
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The Pecularities of Correlation Between Insulin Resistance, Carbohydrate and Lipid Metabolism Indices in Patients with Graves'disease [PDF]
, 2017 Aim. The number of patients with endocrine disorders in the world, in particular, Graves' disease is continuously increasing. Recent studies have determined the fact of insulin resistance in thyroid disorders.
Kikhtyak, O. (Olesya) +2 more
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Treatment With Thyroid Hormone [PDF]
Endocrine Reviews, 2014 Thyroid hormone deficiency can have important repercussions. Treatment with thyroid hormone in replacement doses is essential in patients with hypothyroidism. In this review, we critically discuss the thyroid hormone formulations that are available and approaches to correct replacement therapy with thyroid hormone in primary and central hypothyroidism ...
BIONDI, BERNADETTE, Wartofsky L.
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Role of maternal thyroid hormones in the developing neocortex and during human evolution
Frontiers in Neuroanatomy, 2013 The importance of thyroid hormones during brain development has been appreciated for many decades. In humans, low levels of circulating maternal thyroid hormones, e.g.
Denise eStenzel, Wieland B eHuttner
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Bisphenols and Thyroid Hormone [PDF]
Endocrinology and Metabolism, 2019 In recent decades, attention has been directed toward the effects of bisphenol A (BPA) on human health. BPA has estrogenic activity and is regarded as a representative endocrine disruptor.
Min Joo Kim, Young Joo Park
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