Results 131 to 140 of about 1,914,121 (297)

Effect of progestin on thyroid function in female Wistar rats

Frontiers in Endocrinology
IntroductionTo characterize the influence of female-specific hormones on women’s thyroid function, the study investigated the influence of extra progestin from oral contraceptives on inducing thyroid dysfunction.MethodsSixty female Wistar rats were ...
Honglei Xie, Tingting Qian, Tingting Qian, Lanchun Liu, Rong Sun, Wenjing Che, Meng Zhao, Xin Hou, Haowen Pan, Yue Su, Jia Li, Xiaoqiu Dong, Xiaoqiu Dong, Peng Liu, Peng Liu   +14 more
doaj   +1 more source

Comprehensive exploration of unexplained dyspnoea in subjects with normal ejection fraction and low natriuretic peptides

ESC Heart Failure, Volume 12, Issue 2, Page 879-887, April 2025.
Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Emmanuelle Berthelot, Tarek Laouar, Antoine Beurnier, Nataliya Hrynchynshyn, Jean Christophe Eicher, Jean‐Michel Tartière, Patrick Jourdain, Olivier Lairez, Barnabas Gellen   +8 more
wiley   +1 more source

Temperature homeostasis disruption and hypothalamic alterations in experimental drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia, Akash Bera, Omar Mamad, James D. Mills, Benjamin Villasana‐Salazar, Giada Lavigna, Edoardo Micotti, Manuela Conticello, Asmin Alam, Roberto Chiesa, Francesca Pagani, Roberta Frapolli, Angelo M. Lavecchia, Christodoulos Xinaris, Eleonora Aronica, Andre Altmann, Teresa Ravizza, Sanjay M. Sisodiya, David C. Henshall, Annamaria Vezzani   +19 more
wiley   +1 more source

Maladaptive Weight‐Related Compensatory Behaviours Among Individuals Undergoing Metabolic and Bariatric Surgery

European Eating Disorders Review, EarlyView.
ABSTRACT Introduction Little is known about maladaptive, weight‐related compensatory behaviours (CB) among individuals undergoing metabolic and bariatric surgery (MBS). This brief report examined CB typically associated with restrictive types of eating disorders, including fasting (≥ 8 hours), self‐induced vomiting, and misuse of laxatives and ...
Deborah Lynn Reas, Selma Øverland Lie, Tom Mala, Ingela Lundin Kvalem   +3 more
wiley   +1 more source

Different Forms of Hypothyroidism in Infants with Maternal Graves' Disease

Journal of the ASEAN Federation of Endocrine Societies
Infants of mothers with Graves’ disease (GD) may develop central hypothyroidism (CH) due to exposure of the foetal hypothalamic-pituitary-thyroid axis to higher-than-normal thyroid hormone concentrations, primary hypothyroidism (PH) due to ...
Alexis Anand Dass Lordudass, Jeanne Sze-Lyn Wong, Nalini Selveindran, Janet Yeow Hua Hong   +3 more
doaj   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Embodied attachments: IVF, the maternal body, and the making of embryo kinship

Feminist Anthropology, EarlyView.
Abstract Within the sphere of IVF (in vitro fertilization), there is increasing concern about the stockpiles of frozen embryos held in clinics across the country. This normative discourse tends to take the patient‐embryo relationship for granted, with salient political consequences for current embryo ‘personhood’ debates.
Manon Lefevre
wiley   +1 more source

Modified Chromenes as Precursors to TAAR Regulators [PDF]

, 2011
200 million people worldwide are living with a thyroid disorder related to a hormonal imbalance. Symptoms of this imbalance include deviations from normal heart rates and metabolic rates.
Lehmann, Jonathan, Hart, Matthew
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