Results 91 to 100 of about 2,758,127 (153)

A Subtype-Selective Thyromimetic Designed to Bind a Mutant Thyroid Hormone Receptor Implicated in Resistance to Thyroid Hormone

, 2016
A Subtype-Selective Thyromimetic Designed to Bind a Mutant Thyroid Hormone Receptor Implicated in Resistance to Thyroid ...
Hai Fen Ye (2983362), John T. Koh (2310790), Kathryn E. O'Reill (2983359)   +2 more
core   +1 more source

Resistance to Thyroid Hormone in Crohn's Disease: A Clinical Challenge of Refractory Thyroid Stimulating Hormone Elevation and Therapeutic Dilemmas

Clinical Case Reports
Thyroid hormone resistance (RTH) is a rare genetic disorder characterized by diminished responsiveness of target tissues to thyroid hormones, primarily due to mutations in the thyroid hormone receptor‐beta (TR‐β) gene.
Ahmad Al‐Bitar, Dana Al‐Masalma, Moumen Alkarkoukly, Mohammad Al‐Hawasli   +3 more
doaj   +1 more source

Thyroid Hormone Resistance in children

, 2003
Thyroid Hormone Resistance (RTH) is characterized by the diminished response of thyroid hormone-responsive tissues in varying degrees in association with elevated serum levels of total and free T4 and T3 and inappropriately normal or elevated TSH levels.
ERCAN, Oya, Laron, Z., Krassas, G., Ercal, D., Berberoglu, M.   +4 more
core  

Computational investigation of Crateva religiosa bark phytoconstituents as potential modulators of Hyperthyroidism

Discover Chemistry
Crateva religiosa possesses a diverse array of biologically and pharmacologically active phytoconstituents in its bark, including stigmasterol, β-k-strophanthin, drebyssogenin, β-sitosterol, lupeol, and giganteumgenin.
Sittarthan Viswanathan, Jayaraman Rajangam, Gowrishankar Jayabalan   +2 more
doaj   +1 more source

Thyroid hormone resistance syndrome with P453T mutation in thyroid hormone receptor β gene: A pedigree report. [PDF]

Medicine (Baltimore), 2020
Yusufu A, Chen WJ, Zhang MC.
europepmc   +1 more source

Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration. [PDF]

Cell Prolif, 2020
Perra A, Kowalik MA, Cabras L, Runfola M, Sestito S, Migliore C, Giordano S, Chiellini G, Rapposelli S, Columbano A.   +9 more
europepmc   +1 more source

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH). [PDF]

PLoS One, 2020
Luong XG, Stevens SK, Jekle A, Lin TI, Gupta K, Misner D, Chanda S, Mukherjee S, Williams C, Stoycheva A, Blatt LM, Beigelman LN, Symons JA, Raboisson P, McGowan D, Vandyck K, Deval J.   +16 more
europepmc   +1 more source

Thyroid Hormone Receptor β Inhibits Self-Renewal Capacity of Breast Cancer Stem Cells. [PDF]

Thyroid, 2020
López-Mateo I, Alonso-Merino E, Suarez-Cabrera C, Park JW, Cheng SY, Alemany S, Paramio JM, Aranda A.   +7 more
europepmc   +1 more source

Novel Thyroid Hormone Receptor β Gene Variant (F245L) Causing Mild Resistance to Thyroid Hormone. [PDF]

JCEM Case Rep
Yamagami K, Kanamoto N, Yamashita Y, Sasai Y, Tagami T.   +4 more
europepmc   +1 more source

KYLO-0603, a novel liver-targeting, thyroid hormone receptor-β agonist for the inhibition of MASH progression. [PDF]

PLoS One
Lu X, Wang S, Du Y, Xie B, Chen Q, Lin J, Chen B, Cui K.   +7 more
europepmc   +1 more source