Results 141 to 150 of about 2,553,881 (244)

Strategies for enhancing sensitivity in lateral flow assays

VIEW, EarlyView.
Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed, Jacopo Giaretta, Syamak Farajikhah, Fariba Dehghani   +3 more
wiley   +1 more source

Thyroid hormone acts independently of the thyroid hormone receptor beta in hepatocytes to improve systemic insulin sensitivity. [PDF]

Hepatol Commun
van der Spek AH, Ritter MJ, Amano I, de Oliveira LS, Kaserman JE, Cespedes IS, Vierling T, Wilson AA, Hollenberg AN.   +8 more
europepmc   +1 more source

A mutation in thyroid hormone receptor beta causing "resistance to thyroid hormone" in a neonate

, 2010
Resistance to thyroid hormone (RTH) is an Inherited syndrome characterized by reduced tissue responsiveness to thyroid hormones. The main defects are due to mutations In thyroid hormone receptor beta (TRbeta). A male, term neonate was admitted because of

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Living Together, Loving Apart: Health, Sexuality and Relationships in Middle‐Aged and Older Men in Europe

Andrology, EarlyView.
ABSTRACT Background Over time, family structures have grown more complex, diversifying adult relationships. While research has compared marital, cohabiting and living apart together relationships based on quality and health, less is known about their sexual dynamics.
Clotilde Sparano, Giammarco Alderotti, Giulia Rastrelli, Giovanni Corona, Leen Antonio, Felipe F. Casanueva, Aleksander Giwercman, Thang S. Han, Ilpo T. Huhtaniemi, Chiara Lucchi, Terence O'Neill, Jolanta Słowikowska‐Hilczer, Jos Tournoy, Dirk Vanderschueren, Frederick Wu, Daniele Vignoli, Mario Maggi   +16 more
wiley   +1 more source

Effects of perfluoro hexane sulfonic acid (PFHxS) exposure on embryo development and energy metabolism of zebrafish

Siliao yanjiu
The experiment aimed to investigate the effects of perfluoro hexane sulfonic acid (PFHxS) exposure on embryo development and energy metabolism of zebrafish.
BAI Shuangqian, LI Tingyin, BI Baoliang, HU Qing   +3 more
doaj  

Central thyroid hormone receptor-beta: Sensitivity to alcohol and a role in regulating alcohol drinking. [PDF]

Horm Behav
Johnson MC, Nipper MA, Abshire KM, Rehmann JE, Zweig JA, Vu TN, Bell MA, Banerji T, Scanlan TS, Ryabinin AE, Walker DM.   +10 more
europepmc   +1 more source

Thyroid Hormone Receptor Beta Induces a Tumor-Suppressive Program in Anaplastic Thyroid Cancer. [PDF]

Mol Cancer Res, 2020
Bolf EL, Gillis NE, Davidson CD, Rodriguez PD, Cozzens L, Tomczak JA, Frietze S, Carr FE.   +7 more
europepmc   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Thyroid hormone receptor beta signaling is a targetable driver of prostate cancer growth. [PDF]

Mol Cancer
Fesiuk A, Pölöske D, de Araujo ED, Frere GA, Wright TB, Tin G, Raouf YS, Olaoye OO, Park JS, Blavet N, Tichý B, Schlederer M, Högler S, Wolf M, Philippe C, Aksoy O, Varady A, Mata AM, Varenicja M, Szabó B, Weiss T, Wasinger G, Redmer T, Neubauer HA, Susani M, Spielvogel CP, Ning J, Dahlhoff M, Schepelmann M, Kennedy R, Moriggl R, Brown G, Persson J, Gerner C, Bystry V, Hollóczki O, Heery DM, Gunning PT, Merkel O, Hantusch B, Kenner L.   +40 more
europepmc   +1 more source

Thyroid Hormone Receptor Beta Suppresses PI3K and Metabolic Signaling in Thyroid Cancer

, 2019
11:00 AM11:00am-1:00pmGraduateThyroid cancer is the most common endocrine malignancy, and the rate has been increasing over the past few decades. A commonly unregulated pathway in poorly differentiated thyroid cancer is PI3K signaling.
Davidson, Cole
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