Results 151 to 160 of about 2,553,881 (244)

The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari, Leonardo Dalla Valentina, Cristina Felicani, Filippo Gabrielli, Simonetta Lugari, Giovanni Corona, Paolo Ventura, Manuela Simoni, Fabio Nascimbeni, Daniele Santi   +9 more
wiley   +1 more source

Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerio (zebrafish). [PDF]

PLoS Genet, 2020
Deveau C, Jiao X, Suzuki SC, Krishnakumar A, Yoshimatsu T, Hejtmancik JF, Hejtmancik JF, Nelson RF.   +7 more
europepmc   +1 more source

Hypogonadism in Cisgender Men Living With HIV: Prevalence, Clinical and Metabolic Features

Andrology, EarlyView.
ABSTRACT Background Hypogonadism is frequently observed in men living with human immunodeficiency virus (HIV), although its prevalence, etiology, and predictors remain incompletely understood. Objective To evaluate the prevalence of hypogonadism and its association with metabolic factors in men living with HIV (MLWH), on stable antiretroviral therapy ...
Felipe Augusto Azevedo Leao, Gabriel Cabreira Nunes, Manuela Almeida Ribeiro, Luiza Costa da Fonseca, Aline Cristina Miranda Marinho Costa, Mateus Rodrigues Westin, Unai Tupinambas, Milena Maria Moreira Guimaraes, Leticia Ferreira Gontijo Silveira   +8 more
wiley   +1 more source

Autoimmune thyroiditis promotes breast cancer progression: exploratory role of thyroid hormone receptor beta signaling disruption. [PDF]

Breast Cancer Res
Li S, Jiang QL, Gong HZ, Zeng Y, Jiang J.   +4 more
europepmc   +1 more source

Mutation of the Thyroid Hormone Receptor Beta Gene (<i>THRB</i>) Causes Vitelliform Macular Dystrophy with High Intrafamilial Variability. [PDF]

Genes (Basel)
Mahler EA, Moeller LC, Wall K, Saßmannshausen M, Kron B, Bolz HJ, Holz FG, Herrmann P.   +7 more
europepmc   +1 more source

Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival. [PDF]

BMC Cancer, 2020
Piqué DG, Greally JM, Mar JC.
europepmc   +1 more source

TSHR (thyroid stimulating hormone receptor).

, 2009
TSHR (Thyroid Stimulating Hormone Receptor) gene DNA: position, structure, transcription Protein: structure, expression, localization, function Mutations: somatic and germinal mutations Disease/oncogenesis: Thyroid adenoma, Toxic multinodular goiter (
IOSCO, CARMELA, RHODEN, KERRY JANE
core  

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Thyroid hormone receptor beta-2 (TRβ2) overexpression modulates photoreceptor phenotype diversity in a ligand-dependent manner. [PDF]

Front Cell Dev Biol
Owusu Poku E, Fonte MR, Jensen TJ, Inman SP, Mackin RD, Stenkamp DL.   +5 more
europepmc   +1 more source

Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders. [PDF]

Front Med (Lausanne), 2020
Saponaro F, Sestito S, Runfola M, Rapposelli S, Chiellini G.   +4 more
europepmc   +1 more source