Results 91 to 100 of about 42,240 (230)

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

A woman with Pituitary Microadenoma: May Thyroid Hormone Resistance be a Cause? A case report and Review of the Literature

Endocrinology Research and Practice, 2011
Resistance to thyroid hormone (RTH) is an inherited syndrome characterized by reduced responsiveness of target tissues to thyroid hormone. It is usually first suspected due to findings of high serum free thyroxine (T4) and free triiodothyronine (T3 ...
Ece Harman, Ilgın YILDIRIM ŞİMŞİR, Murat Tanju Zungur, Ahmet Gökhan Özgen   +3 more
doaj   +2 more sources

Thyrotropin/growth hormone co-secreting pituitary adenoma with pancytopenia: a case report

Journal of Medical Case Reports
Background Thyroid-stimulating hormone (TSH)-secreting pituitary adenoma (TSHoma) is a rare functional pituitary tumor that secretes TSH independently, thus stimulating the synthesis and secretion of thyroid hormone. Its clinical manifestation is central
Jie Liu, Yanhui Zhu, Yu Wei, Lei Yu, Yu Li, Qiong Wang, Langen Zhuang, Guoxi Jin, Xiaoyan Pei   +8 more
doaj   +1 more source

Resistance to thyroid hormone syndrome with developmental disorders in two children

中国当代儿科杂志
Patient 1, a 4-year-old boy, presented with delayed language development. Persistently elevated free triiodothyronine (FT3) and free thyroxine (FT4) were found, with normal or elevated thyroid-stimulating hormone (TSH). A de novo heterozygous mutation in
LIAO Lin-Ying, LI Xing-Fang, ZHANG Xing-Xing   +2 more
doaj   +1 more source

Syndromes of thyroid hormone resistance [PDF]

Clinical Endocrinology, 1991
openaire   +2 more sources

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

Clinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams, Bonnie Grant, Richard Quinton, Channa N. Jayasena   +3 more
wiley   +1 more source

A Case of Thyroid Hormone Resistance Syndrome with a Novel Mutation (c.947G>a) in the THRB Gene: Experience in Diagnosis and Treatment

International Medical Case Reports Journal
Jie Liu, Yu Wei, Yanhui Zhu, Yu Li, Qiong Wang, Lei Yu, Langen Zhuang, Guoxi Jin, Xiaoyan Pei Department of Endocrinology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui Province, People’s Republic of ChinaCorrespondence: Guoxi
Liu J, Wei Y, Zhu Y, Li Y, Wang Q, Yu L, Zhuang L, Jin G, Pei X   +8 more
doaj  

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source

Correlation of Thyroid Hormone Levels and Sensitivity With Metabolic Syndrome in Older Adults

Journal of Diabetes
Objective Previous studies have shown that thyroid function is associated with metabolic syndrome (MetS), but this association remains poorly understood in older adults.
Fengjuan Hu, Hu Liu, Linlin Gu, Shuli Jia, Lixing Zhou, Wanyu Zhao, Xiaolei Liu, Birong Dong   +7 more
doaj   +1 more source

Optic nerve hypoplasia and septo‐optic‐pituitary dysplasia

Developmental Medicine &Child Neurology, EarlyView.
Optic nerve hypoplasia and septo‐optic‐pituitary dysplasia. Abstract The presence of a small optic disc on funduscopy is prerequisite for the diagnosis of optic nerve hypoplasia (ONH). Visual acuity may be normal. However, amblyopia can occur in ONH. A relative afferent pupillary light defect indicates unilateral or asymmetrical ONH.
Michael S. Salman
wiley   +1 more source