Results 91 to 100 of about 39,493 (235)

Importance of Hypercortisolism in BP Control, Cardiovascular Risk and in Patients With Difficult‐to‐Control Hypertension: An Overview for Primary Care Physicians

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Hypertension remains one of the most prevalent and consequential modifiable cardiovascular risk factors worldwide, affecting approximately 1.28 billion adults globally and nearly half of the United States population. Despite the availability of effective therapies, optimal blood pressure control is achieved in fewer than one in four ...
Matthew A. Cavender
wiley   +1 more source

A Case of Thyroid Hormone Resistance Syndrome with a Novel Mutation (c.947G>a) in the THRB Gene: Experience in Diagnosis and Treatment

open access: yesInternational Medical Case Reports Journal
Jie Liu, Yu Wei, Yanhui Zhu, Yu Li, Qiong Wang, Lei Yu, Langen Zhuang, Guoxi Jin, Xiaoyan Pei Department of Endocrinology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui Province, People’s Republic of ChinaCorrespondence: Guoxi
Liu J   +8 more
doaj  

Association between sensitivity to thyroid hormone indices and frailty in the elderly: a cross-sectional study

open access: yesFrontiers in Endocrinology
ObjectiveFrailty is a prevalent geriatric syndrome that affects several systems and lacks accurate evaluation indications. Previous studies on the association between thyroid function and frailty have contradicted.
Xinyu Qi   +13 more
doaj   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib   +3 more
wiley   +1 more source

Insulin, Semaglutide and Dapagliflozin in Adults With Type 1 Diabetes: Design and Methods of Triple Therapy for Type 1 Diabetes (TTT1)—An International Phase 3 Clinical Trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Attaining target glycaemia can be a challenge in Type 1 Diabetes (T1D) due to insulin‐induced weight gain. Adjunct therapy with modern glucose‐lowering agents developed for type 2 diabetes (T2D) has great potential but may be insufficiently efficacious and carries risks of hypoglycaemia and ketosis.
Joseph G. Timmons   +11 more
wiley   +1 more source

Is It Time to Expand Newborn Screening for Congenital Hypothyroidism to Other Rare Thyroid Diseases?

open access: yesInternational Journal of Neonatal Screening
Congenital hypothyroidism (CH) is a heterogeneous condition present at birth, resulting in severe-to-mild thyroid hormone deficiency. This condition is difficult to recognize shortly after birth.
Antonella Olivieri   +3 more
doaj   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

open access: yesThe FEBS Journal, EarlyView.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger   +3 more
wiley   +1 more source

Van Wyk–Grumbach Syndrome With Insulin Resistance in Children: A Case Report

open access: yesClinical Case Reports
This case reports an 8 year‐5 month‐old girl diagnosed with Van Wyk–Grumbach Syndrome (VWGS) and co‐existing insulin resistance from China. The patient achieved complete resolution of clinical manifestations with thyroid hormone replacement therapy ...
Hui Liu   +5 more
doaj   +1 more source

Effect of impaired sensitivity to thyroid hormones on the risk of insulin resistance and dyslipidemia in polycystic ovary syndrome patients

open access: yesGynecological Endocrinology
This study assessed thyroid hormone sensitivity indices (THSI) and their impact on insulin resistance (IR) and dyslipidemia risk in euthyroid individuals with polycystic ovary syndrome (PCOS).A retrospective analysis of 226 PCOS patients and 189 healthy ...
Yang You   +4 more
doaj   +1 more source

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