Results 101 to 110 of about 42,240 (230)

Association between sensitivity to thyroid hormone indices and frailty in the elderly: a cross-sectional study

Frontiers in Endocrinology
ObjectiveFrailty is a prevalent geriatric syndrome that affects several systems and lacks accurate evaluation indications. Previous studies on the association between thyroid function and frailty have contradicted.
Xinyu Qi, Jia Fang, Jiru Zhang, Jihai Chen, Jihai Chen, Daowen Zhang, Runqing Shi, Yusheng Zhang, Lijun Wei, Lu Yan, Yunlu Sheng, Guoxian Ding, Xiaojun Ouyang, Yu Duan   +13 more
doaj   +1 more source

Multisystem developmental abnormalities and insulin resistance in ADTKD‐HNF1B with the p.E105K variant: A clinical conundrum

Diabetic Medicine, EarlyView.
Abstract Aims HNF1B variants cause autosomal dominant tubulointerstitial kidney disease (ADTKD‐HNF1B), but the phenotypic spectrum of variants of uncertain significance (VUS) remains incompletely defined. We aimed to characterise the multisystem phenotype associated with the HNF1B p.E105K variant and to examine the mechanism underlying insulin ...
YunZe Wang, KangChun Xu, PengFei Liu, Bin Wang, Yan Yang, ShanZhai Wei   +5 more
wiley   +1 more source

Thyroid hormone resistance syndrome with P453T mutation in thyroid hormone receptor β gene: A pedigree report. [PDF]

Medicine (Baltimore), 2020
Yusufu A, Chen WJ, Zhang MC.
europepmc   +1 more source

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

Hepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuuki Azuma, Tomonobu Hioki, Yusuke Morita, Keisuke Sakaguchi, Nobuhiro Fujita, Takamori Kakino, Ayako Ishikita, Kenichiro Yamamura, Ichiro Sakamoto, Kousei Ishigami, Kohtaro Abe, Yoshihiro Ogawa   +14 more
wiley   +1 more source

Is It Time to Expand Newborn Screening for Congenital Hypothyroidism to Other Rare Thyroid Diseases?

International Journal of Neonatal Screening
Congenital hypothyroidism (CH) is a heterogeneous condition present at birth, resulting in severe-to-mild thyroid hormone deficiency. This condition is difficult to recognize shortly after birth.
Antonella Olivieri, Maria Cristina Vigone, Mariacarolina Salerno, Luca Persani   +3 more
doaj   +1 more source

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

International Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta, Jaspreet Kaur, Amanda Liddy, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Van Wyk–Grumbach Syndrome With Insulin Resistance in Children: A Case Report

Clinical Case Reports
This case reports an 8 year‐5 month‐old girl diagnosed with Van Wyk–Grumbach Syndrome (VWGS) and co‐existing insulin resistance from China. The patient achieved complete resolution of clinical manifestations with thyroid hormone replacement therapy ...
Hui Liu, Gaojie Liu, Hui Wang, Weicai Suo, Yizhong Wang, Hongfang Ding   +5 more
doaj   +1 more source

Effect of impaired sensitivity to thyroid hormones on the risk of insulin resistance and dyslipidemia in polycystic ovary syndrome patients

Gynecological Endocrinology
This study assessed thyroid hormone sensitivity indices (THSI) and their impact on insulin resistance (IR) and dyslipidemia risk in euthyroid individuals with polycystic ovary syndrome (PCOS).A retrospective analysis of 226 PCOS patients and 189 healthy ...
Yang You, Xiaohui Li, Zaixin Guo, Xinyu Hong, Qi Yu   +4 more
doaj   +1 more source

Association of atherogenic index of plasma with gestational diabetes mellitus and birth weight outcomes, and the mediating role of blood glucose

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims This study aimed to examine the associations of maternal first‐trimester atherogenic index of plasma (AIP) with gestational diabetes mellitus (GDM) and birth weight outcomes, and the mediating role of second‐trimester blood glucose. Methods This prospective cohort study included 5,706 pregnant women without pre‐existing diabetes or other ...
Doudou Zhao, Yanfang Song, Nan Li, Yu Zhang, Yiting Li, Kangxin Wang, Yang Mi, Lei Shang, Pengfei Qu   +8 more
wiley   +1 more source

Association between thyroid feedback quantile‐based index and the risk of in‐hospital amputation in patients with diabetic foot ulcer

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the relationship between the thyroid feedback quantile‐based index (TFQI) and the risk of amputation during hospitalization in patients with diabetic foot ulcers (DFU). Methods This single‐center retrospective study included 381 hospitalized patients with DFU and normal thyroid function.
Jiale Wang, Yujie Huang, Funeng Wang, Meiling Lao, Lijun Lan, Peiling Liang   +5 more
wiley   +1 more source