Results 101 to 110 of about 39,898 (284)

Association between sensitivity to thyroid hormone indices and frailty in the elderly: a cross-sectional study

Frontiers in Endocrinology
ObjectiveFrailty is a prevalent geriatric syndrome that affects several systems and lacks accurate evaluation indications. Previous studies on the association between thyroid function and frailty have contradicted.
Xinyu Qi, Jia Fang, Jiru Zhang, Jihai Chen, Jihai Chen, Daowen Zhang, Runqing Shi, Yusheng Zhang, Lijun Wei, Lu Yan, Yunlu Sheng, Guoxian Ding, Xiaojun Ouyang, Yu Duan   +13 more
doaj   +1 more source

Thyroid hormone resistance syndrome caused by a novel mutation in the thyroid hormone receptor-beta gene (THRB, GLU457LYS) treated with methimazole. [PDF]

Clin Case Rep, 2022
Rezgani I, Chihaoui M, Oueslati I, Chaker F, Nagi S, Yazidi M.   +5 more
europepmc   +1 more source

Semaglutide Injection in Indian Patients With Type 2 Diabetes Mellitus: A Randomised, Phase III, Active‐Controlled Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To evaluate the efficacy, safety and immunogenicity of semaglutide injection (synthetic) (Test group) compared with the Reference semaglutide injection [Ozempic, (Reference group)] in Indian patients with Type 2 diabetes mellitus (T2DM).
Unnikrishnan Ambika Gopalakrishnan, Ameya Sudhakar Joshi, Richa Giri, Shalin Jagdeep Shah, Jitendra Shukla, Sanjiv Maheshwari, Rekha M. Chowdaiah, Manish Kumar Singh, Aditya Srirang Bari, Niranjan Pandurang Pathak, Akash Nitinbhai Shah, Shweta Bhandari, Ambanna Gowda, Ambrish Chandrappa, Pravin Dinkar Supe, Bharat Das, Prabhat Kumar Sharma, Mehul Kalubhai Virani, Prakash Harishchandra Kurmi, Gayatri Amit Ghanekar, Mani Deepathi Dasari, Banshidhar Sahoo, Sanjay Kumar Jangid, Prakash Sadashiv Shende, Sandesh Sahebarao Patil, Avinash Narayan Kumbhar, Shrikant Vishnu Deshpande, Madhusudhan Chennappa, Nitesh Chandubhai Patel, Dipesh Sonawane, Dipak Patil, Sucheta Pandit, Pravin Ghadge, Suyog Mehta   +33 more
wiley   +1 more source

Short‐Term Combined Treatment With Tirzepatide and Metformin for Overweight/Obese Chinese Women With Polycystic Ovary Syndrome: A Prospective, Open‐Label, Randomised Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study aimed to assess the effects of low‐dose tirzepatide combined with metformin (COM) versus metformin (MET) monotherapy in overweight/obese women with polycystic ovary syndrome (PCOS). Materials and Methods Sixty overweight/obese women with PCOS were randomised to the MET group (1000 mg twice daily [BID]) or the COM group (MET ...
Zhuoran Yang, Yuxin Xu, Hu Du, Wenya Liu, Haiyan Chen, Dongfang Liu, Lili Zhang, Cong Wang   +7 more
wiley   +1 more source

Is It Time to Expand Newborn Screening for Congenital Hypothyroidism to Other Rare Thyroid Diseases?

International Journal of Neonatal Screening
Congenital hypothyroidism (CH) is a heterogeneous condition present at birth, resulting in severe-to-mild thyroid hormone deficiency. This condition is difficult to recognize shortly after birth.
Antonella Olivieri, Maria Cristina Vigone, Mariacarolina Salerno, Luca Persani   +3 more
doaj   +1 more source

Diagnosis and management of equine metabolic syndrome

Equine Veterinary Education, EarlyView.
Summary Equine metabolic syndrome (EMS) is a prevalent endocrine disorder that increases the risk of hyperinsulinaemia‐associated laminitis (HAL), the most common and clinically significant form of laminitis. The central pathological feature of EMS is insulin dysregulation (ID), which encompasses basal or postprandial hyperinsulinaemia and tissue ...
F. R. Bertin
wiley   +1 more source

Van Wyk–Grumbach Syndrome With Insulin Resistance in Children: A Case Report

Clinical Case Reports
This case reports an 8 year‐5 month‐old girl diagnosed with Van Wyk–Grumbach Syndrome (VWGS) and co‐existing insulin resistance from China. The patient achieved complete resolution of clinical manifestations with thyroid hormone replacement therapy ...
Hui Liu, Gaojie Liu, Hui Wang, Weicai Suo, Yizhong Wang, Hongfang Ding   +5 more
doaj   +1 more source

Effect of impaired sensitivity to thyroid hormones on the risk of insulin resistance and dyslipidemia in polycystic ovary syndrome patients

Gynecological Endocrinology
This study assessed thyroid hormone sensitivity indices (THSI) and their impact on insulin resistance (IR) and dyslipidemia risk in euthyroid individuals with polycystic ovary syndrome (PCOS).A retrospective analysis of 226 PCOS patients and 189 healthy ...
Yang You, Xiaohui Li, Zaixin Guo, Xinyu Hong, Qi Yu   +4 more
doaj   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Mutational Landscape of Resistance to Thyroid Hormone Beta (RTHβ)

, 2019
Resistance to thyroid hormone beta (RTHβ) is a syndrome characterized by reduced responsiveness of peripheral tissues to thyroid hormone (TH). In most cases, the disorder is associated with germline pathogenic variants in the thyroid hormone receptor ...
Paragliola R. M.
core   +1 more source