Results 121 to 130 of about 39,493 (235)
Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi +12 more
wiley +1 more source
R243W Mutation in Thyroid Hormone Resistance Syndrome Beta: A Case Report. [PDF]
Ong JC +4 more
europepmc +1 more source
Abstract figure legend Thyroid antibody positivity (TAb+) in pregnancy is associated with adverse pregnancy outcomes, but the mechanisms are unclear. This study developed a rodent model of TAb+ in pregnancy, induced prior to mating so that TAb+ exposure occurred throughout the pregnancy. TAb+ did not alter thyroid hormone concentrations and had minimal
Rebecca L. Brady +11 more
wiley +1 more source
A Case of Thyroid Hormone Resistance Syndrome with a Novel Mutation (c.947G>a) in the THRB Gene: Experience in Diagnosis and Treatment. [PDF]
Liu J +8 more
europepmc +1 more source
In this population‐based study of 883 women, AMH declined less with age in women with PCOS than in healthy women. Higher AMH may protect older healthy women from T2DM but indicates elevated metabolic risk in younger women with PCOS, supporting its role as a life‐course biomarker for metabolic risk stratification.
Fahimeh Ramezani Tehrani +5 more
wiley +1 more source
[A case of thyroid hormone resistance syndrome due to previously undescribed mutation in the <i>THRA</i> gene]. [PDF]
Skorodok YL +7 more
europepmc +1 more source
A clinically aligned two‐stage machine learning framework integrates preoperative and perioperative features to predict hungry bone syndrome after parathyroidectomy. Explainable risk stratification may support individualised calcium management and early intervention for high‐risk patients.
Shih‐Min Yin +10 more
wiley +1 more source
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed +8 more
wiley +1 more source
Abstract Aim Schizophrenia imposes significant economic and social burdens, often resulting in prolonged inpatient length of stay (LOS), particularly for treatment‐resistant cases. This study aimed to identify clinical, demographic, and social factors associated with prolonged LOS in a Canadian tertiary schizophrenia inpatient unit to highlight ...
Naista Zhand +5 more
wiley +1 more source

