Results 81 to 90 of about 39,898 (284)

Thyroid Hormone Resistance Syndrome: A Case Report with Literature Review

Resistance to thyroid hormone receptor beta (THRβ) is a rare condition causing abnormal thyroid function tests (TFTs) characterized by elevated thyroid hormone levels with unsuppressed Thyroid Stimulating Hormone (TSH).
Ahmed, Nourhan, Kela, Genevieve, Gazya, Hossam, Hassan, Ahmed, Mostafa, Hamed Abdelma’aboud   +4 more
core   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Levodopa induces thyroid function regulation in a patient with thyroid hormone resistance and Parkinson’s disease: a case report

Frontiers in Endocrinology
IntroductionThyroid hormone resistance (THR) is a rare genetic syndrome characterized by reduced sensitivity to thyroid hormones. Patients may be asymptomatic, although clinical manifestations depend on the THR subtype.
Gabriela Rozo-Paz, Clara Maria Ruiz-Forero, José David Suárez-Mera, Guillermo Monsalve Duarte, William Kattah Calderón   +4 more
doaj   +1 more source

A rare syndrome: Thyroid hormone resistance

Dicle Medical Journal / Dicle Tip Dergisi, 2011
Tiroid hormon direnci sendromu (RTH) genellikle otozomal dominant kalitim gösteren nadir bir hastalıktır. Tiroid hormon direnci olan hastalar genellikle ötiroid olurlar fakat nadir de olsa tirotoksikoz veya hipotiroidizm belirti ve bulguları ile seyredilebilir. Biz bu yazıda ilginç bir sendrom olarak tiroid hormon direnci olan fakat aile öyküsü olmayan
KİBAR, Yunus İlyas, ARIKAN, Şenay, ÇARLIOĞLU, Ayşe, ÖZTÜRK, Yasin, TAY, Ahmet, AYHAN, Mehmet Emin   +5 more
openaire   +2 more sources

Prolactin in high‐metabolic risk pregnancies: Associations with maternal obesity and metabolic health

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Higher maternal BMI before and during early pregnancy is associated with lower prolactin levels across gestation and a reduced prolactin rise. Prolactin in pregnancy may reflect maternal metabolic health and has potential relevance to lactation outcomes.
Kate Rassie, Simon Alesi, Adriana C. H. Neven, Taitum Mason, Eveline Jona, Stacey J. Ellery, Joanne Enticott, Aya Mousa, Anju E. Joham, David Simmons, Helena Teede, on behalf of the TOBOGM Core Investigator Group   +11 more
wiley   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Thyroid Hormone Resistance Syndrome: From Molecular Mechanisms to Its Potential Contribution to Hypertension. [PDF]

Cureus, 2023
Prakash K, Hamid P.
europepmc   +1 more source

Mosaicism of a thyroid hormone receptor-beta gene mutation in resistance to thyroid hormone

, 2006
Context: Heterozygous mutations in thyroid hormone receptor-beta (TR beta) gene are the cause of resistance to thyroid hormone (RTH) in more than 85% of families having the syndrome. In 23% of the families, TR beta gene mutations occur de novo.
Liao, Xiao-Hui, Mamanasiri, Sunee, Demir, TEVFİK, Yesil, Sena, Dumitrescu, Alexandra M., Weiss, Roy E, Weiss, Roy E., Dumitrescu, Alexandra M, Refetoff, Samuel   +8 more
core   +1 more source

Two Novel Mutations In The Thyroid Hormone Receptor β In Patients With Resistance To Thyroid Hormone (rth β): Clinical, Biochemical, And Molecular Data

, 2015
The syndrome of resistance to thyroid hormone (RTH β) is an inherited disorder characterized by variable tissue hyposensitivity to 3,5,30-l-triiodothyronine (T3), with persistent elevation of free-circulating T3 (FT3) and free thyroxine (FT4) levels in ...
Esquiaveto-aun A.M., de Mello M.P., de Lemos-Marini S.H.V., Guerra-junior G., Nakano B.S.L., Zantut-wittmann D.E., Petroli R.J.   +6 more
core   +2 more sources

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source