Three new mutations of thyroid hormone receptor-beta associated with resistance to thyroid hormone
, 1994 Three novel point mutations at nucleotides 1249, 1282, and 1614 (exons 9 and 10) of the human thyroid hormone receptor-beta gene were observed in six individuals affected by the syndrome of resistance to thyroid hormone. All three mutations occurred in a
Pontecorvi, Alfredo
core +1 more source
Does insulin resistance increase thyroid volume in patients with polycystic ovary syndrome?
Archives of Endocrinology and MetabolismObjective To investigate the effect of gonadotropin, sex hormone levels and insulin resistance (IR) on thyroid functions and thyroid volume (TV) in polycystic ovary syndrome (PCOS). Subjects and methods 69 new diagnosed PCOS patients (age 24.82 ± 6.17)
Murat Sahin +6 more
doaj +1 more source
The Turkish Journal of Pediatrics, 2008 Resistance to thyroid hormone (RTH) syndrome is a rare disorder usually inherited as an autosomal dominant trait. The combination of elevated serum levels of free thyroid hormones with elevated thyroid-stimulating hormone (TSH) suggest ...
Sükran Poyrazoğlu +3 more
doaj
Painless destructive thyroiditis in a patient with resistance to thyroid hormone: a case report
Thyroid Research, 2019 Background Resistance to thyroid hormone (RTH) usually features a syndrome of inappropriate secretion of thyroid-stimulating hormone (SITSH) without suppression of the typical high thyroid hormone levels.
Tomoko Nagamine +6 more
doaj +1 more source
Thyroid Hormone Receptor Mutations in Cancer and Resistance to Thyroid Hormone: Perspective and Prognosis [PDF]
, 2011 Thyroid hormone, operating through its receptors, plays crucial roles in the control of normal human physiology and development; deviations from the norm can give rise to disease. Clinical endocrinologists often must confront and correct the consequences
Martin L. Privalsky, Meghan D. Rosen
core +1 more source
Thyroid Hormone Resistance Syndrome: From Molecular Mechanisms to Its Potential Contribution to Hypertension. [PDF]
Cureus, 2023 Prakash K, Hamid P.
europepmc +1 more source
Retrospective analysis and literature review of four cases of thyroid hormone resistance syndrome caused by THRB gene mutation. [PDF]
Transl Pediatr, 2022 Zhang L +8 more
europepmc +1 more source
[Thyroid hormone resistance syndrome].
Arquivos brasileiros de endocrinologia e metabologia, 2005 Resistance to thyroid hormone (RTH) is a syndrome characterized by elevated serum thyroid hormone (TH) levels and elevated or inappropriately normal thyrotropin levels. In general, patients exhibit TH resistance in the pituitary and peripheral tissues.
Gisah A de, Carvalho, Helton E, Ramos
openaire +1 more source
Thyroid Hormone Resistance Syndrome: A Case Report with Literature Review [PDF]
Resistance to thyroid hormone receptor beta (THRβ) is a rare condition causing abnormal thyroid function tests (TFTs) characterized by elevated thyroid hormone levels with unsuppressed Thyroid Stimulating Hormone (TSH).
Ahmed, Nourhan +4 more
core +1 more source
Endocrinology Research and Practice, 2009 Resistance to thyroid hormone (RTH) is an inherited syndrome of reduced sensitivity to thyroid hormone (TH), usually due to mutations in the thyroid hormone receptor (TR) b gene.
Banu Kale Köroğlu +5 more
doaj +2 more sources