Results 141 to 150 of about 188,732 (189)

Quantitative Chemical Exchange Saturation Transfer MRI for Diagnosing Thyroid-Associated Ophthalmopathy Activity: A Prospective Feasibility Study. [PDF]

open access: yesKorean J Radiol
Wang Y   +13 more
europepmc   +1 more source

Teprotumumab for Thyroid-Associated Ophthalmopathy [PDF]

open access: yesNew England Journal of Medicine, 2017
Thyroid-associated ophthalmopathy, a condition commonly associated with Graves' disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns. Inhibition of the insulin-like growth factor I receptor (IGF-IR) is a new therapeutic strategy to attenuate the ...
Mario Salvi   +2 more
exaly   +10 more sources

Glycosaminoglycans in Thyroid-Associated Ophthalmopathy

open access: yesAutoimmunity, 1992
Glycosaminoglycan (GAG) accumulation in the retrobulbar space of patients with thyroid-associated ophthalmopathy (TAO) has been documented in a number of immunohistochemical studies. In order to gain further insight into possible immunopathogenic mechanisms, the influence of humoral immunity on retrobulbar fibroblasts (RF) as GAG producing cells as ...
C Stover, G Kahaly
exaly   +4 more sources

Radioiodine and thyroid-associated ophthalmopathy

open access: yesOrbit, 1996
Particular attention has recently been paid to the relationship between radioiodine administration and the course of thyroid-associated ophthalmopathy (TAO).
Fausto Bogazzi   +2 more
exaly   +2 more sources

Thyroid ophthalmopathy

Current Opinion in Ophthalmology, 1994
Thyroid ophthalmopathy, idiopathic orbital inflammation, and orbital infection can occasionally demonstrate overlapping clinical features. It is essential to distinguish between these processes because appropriate treatments are distinct in each case.
E G, Faktorich, N, Tucker, J M, O'Brien
openaire   +2 more sources

Minimal thyroid ophthalmopathy

Neurology, 1987
We studied six patients with the clinical, sonographic, CT, and biochemical profile of minimal euthyroid Graves' disease (MEGD). This syndrome was characterized clinically by small but obtrusive and measurable amounts of diplopia related to endocrine ophthalmopathy and the conspicuous absence of systemic or laboratory signs of thyrotoxicosis ...
R H, Spector, J A, Carlisle
openaire   +2 more sources

Rituximab for thyroid-associated ophthalmopathy

Cochrane Database of Systematic Reviews, 2013
Thyroid associated ophthalmopathy (TAO) is the most frequent extrathyroidal manifestation of Graves' disease, affecting up to 50% of patients, and has a great impact on quality of life. Rituximab is a human/murine chimeric monoclonal antibody that targets CD20, a transmembrane protein expressed on the surface of pre-B and mature B lymphocytes, but not ...
Neda, Minakaran, Daniel G, Ezra
openaire   +4 more sources

Tear film osmolarity in patients with thyroid ophthalmopathy

open access: yesJapanese Journal of Ophthalmology, 2008
Purpose: To compare tear film osmolarity between patients with thyroid ophthalmopathy and normal healthy ...
Yunus Karakoc
exaly   +2 more sources

Infliximab: A Novel Treatment for Sight-Threatening Thyroid Associated Ophthalmopathy

open access: yesOrbit, 2005
We describe a patient with sight threatening thyroid associated ophthalmopathy (TAO) who was successfully treated with infliximab, an anti-tumour necrosis factor (TNF)-a ...
Philip I. Murray
exaly   +2 more sources

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