Results 151 to 160 of about 188,732 (189)

Results of radiotherapy for thyroid ophthalmopathy

International Journal of Radiation Oncology*Biology*Physics, 1989
Between October, 1978 and August, 1986, 35 patients with thyroid ophthalmopathy were treated with radiotherapy. Twenty-eight patients had treatment with corticosteroids prior to radiotherapy and either progressed on steroids or relapsed during tapering. Seven patients with contraindications to steroids were treated primarily with radiotherapy.
H M, Sandler, J H, Rubenstein, B L, Fowble, R C, Sergott, P J, Savino, T M, Bosley   +5 more
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Management of thyroid ophthalmopathy

Current Opinion in Ophthalmology, 1996
The pathogenesis of thyroid ophthalmopathy and its relation to thyroid gland dysfunction defies elucidation, and thus only palliative therapy exists. If and how antithyroid therapy affects the course of thyroid eye disease remains controversial. Research continues to try to reveal a subset of patients who respond best to corticosteroid or radiation ...
openaire   +2 more sources

Pathogenesis of thyroid-associated ophthalmopathy

Trends in Endocrinology & Metabolism, 1993
Thyroid-associated ophthalmopathy is a complex disease whose pathogenesis is thought to be autoimmune. Evidence has accumulated to implicate lymphocytes, antibodies, and cytokines targeting the orbital tissues whose structural and functional characteristics are unique.
P, Perros, P, Kendall-Taylor
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The pathophysiology of thyroid-associated ophthalmopathy

Ophthalmology Clinics of North America, 2002
TAO is an inflammatory disease of the orbital tissues. The effects of inflammation, mediated through cytokine release, include proliferation of fibroblasts, increased deposition of extracellular matrix, and adipocyte differentiation and proliferation. As a result, edema, enlargement of the extraocular muscles, and increased volume of the orbital soft ...
Mark P, Hatton, Peter A D, Rubin
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Extrathyroidal Manifestations of Thyroid Disease: Thyroid Ophthalmopathy

Neuroimaging Clinics of North America, 2008
Thyroid ophthalmopathy is a common autoimmune, inflammatory disease involving the orbit. Diagnosis is based on the clinical presentation and findings. Imaging, mainly CT and MR imaging, are helpful to reveal the extent of disease and degree of muscle enlargement and to evaluate for complications, such as optic nerve compression.
Hemant, Parmar, Mohannad, Ibrahim
exaly   +3 more sources

The pathogenesis of thyroid-associated ophthalmopathy

Journal of Endocrinology, 1989
Introduction Thyroid-associated ophthalmopathy (TAO) is closely related to Graves' hyperthyroidism and is characterized by periorbital oedema, conjunctival injection, exophthalmos, extraocular muscle dysfunction and, in its severe form, exposure keratitis and optic nerve compression. The extraocular muscles (EOM)
P, Perros, P, Kendall-Taylor
openaire   +2 more sources

Thyroid ophthalmopathy.

Minerva endocrinologica, 2006
Thyroid associated ophthalmopathy (TAO) is an inflammatory orbital disease of autoimmune origin with the potential to cause severe functional and psychosocial effects. It presents one of the most difficult challenges in the clinical practice of ophthalmology. Pathogenesis of the disease is not yet fully understood. It is usually associated with thyroid
J, Levy, R, Sobel, M, Marcus, T, Lifshitz   +3 more
openaire   +1 more source

Treating the thyroid in the presence of Graves’ ophthalmopathy

Best Practice & Research Clinical Endocrinology & Metabolism, 2012
The etiology of Graves' orbitopathy (GO) remains enigmatic. Optimal therapeutic choices for the hyperthyroidism associated with Graves' disease (GD) in the presence of GO remain controversial. Whether antithyroid drugs (ATDs), radioiodine (RAI), or thyroidectomy should be favored in such patients remains debated. Pre-therapy variables such as ethnicity,
Hegedüs, Laszlo, Bonnema, Steen J, Smith, Terry J, Brix, Thomas H   +3 more
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Octreoscan in Thyroid-Associated Ophthalmopathy

Thyroid, 2002
Until recently, there was no imaging technique available that could be considered as a reliable measure of inflammation in thyroid-associated opthalmopathy (TAO). Pentetreotide (a synthetic derivative of somatostatin) labeled with 111In has been used to visualize somatostatin receptors in endocrine-related tumours in vivo.
openaire   +2 more sources

Thyroid-Associated Ophthalmopathy

2011
Eye symptoms are a common feature of Graves’ disease, where the symptoms have an underlying immunological cause. Several designations have been used: endocrine ophthalmopathy, dysthyroid orbitopathy, dysthyroid ophthalmopathy, orbitopathy, infiltrative ophthalmopathy and thyroid-associated ophthalmopathy (TAO).
Ernst Nyström, Gertrud E. B. Berg, Svante K. G. Jansson, Ove Tørring, Stig V. Valdemarsson   +4 more
openaire   +1 more source