Results 41 to 50 of about 8,835 (210)
ABSTRACT Background and Aim Visual impairment represents a major public health concern, affecting millions of individuals worldwide. In recent years, the global burden of eye diseases and vision impairment has continued to grow. This study aims to investigate the trends in eye and adnexa‐related hospital admissions in Lebanon from 2006 to 2019, as ...
Dany Akiki +5 more
wiley +1 more source
Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells [PDF]
Introduction Patients with autoimmune thyroid disease (AITD) show defects in their immune-regulatory mechanisms. Herein we assessed the expression and function of galectin-1 and galectin-9 (Gal-1, Gal-9) in dendritic cells (DCs) from patients with ...
Ana Ramos-Levi +37 more
core +5 more sources
ABSTRACT Background Thyroid‐associated ophthalmopathy (TAO) may lead to severe exophthalmos and dysthyroid optic neuropathy (DON), which can threaten visual function. Orbital decompression surgery is often required when medical therapy is insufficient; however, traditional deep lateral wall decompression techniques remain associated with several ...
Shuo Wu +4 more
wiley +1 more source
Unilateral Grave’s Disease: A Rare Variant [PDF]
Grave’s Disease (GD), an autoimmune disorder, usually presents as diffuse goitre with involvement of both lobes of the thyroid gland. It is characterised by hyperthyroidism, ophthalmopathy and rarely dermopathy.
Arun Pande, Ajay Aggarwal, Roopak Wadhwa
doaj +1 more source
The influence of hepatitis C infection and interferon-α therapy on thyrotropin blocking and stimulating autoantibodies in Graves' ophthalmopathy: a case report [PDF]
Background Hepatitis C virus is a highly immunogenic pathogen often inducing autoimmune activation changes and this can often be further exacerbated by Interferon therapy.
Huy A Tran, Glenn EM Reeves
core +1 more source
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu +12 more
wiley +1 more source
The psychosocial and clinical outcomes following orbital decompression surgery for thyroid eye disease and predictors of change in quality of life [PDF]
Objective: Thyroid eye disease (TED) has been found to reduce quality of life for many patients due to changes in their appearance and vision, although some appear to adjust better than others. This study was designed to investigate whether a patient’s
Ezra, D. G. +5 more
core +1 more source
ABSTRACT Background and Aims CMT1H is a rare, autosomal dominant, demyelinating subtype of CMT caused by variants in FBLN5. Symptomatic cranial nerve involvement has never been reported in patients with CMT1H. Case Report We report a 45‐year‐old woman with a history of long‐standing diplopia.
Georgios Koutsis +11 more
wiley +1 more source
Differential Gene Expression Profiling of Orbital Adipose Tissue in Thyroid Orbitopathy [PDF]
Published under a Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode)PURPOSE. We aimed to determine differentially expressed genes relevant to orbital inflammation and orbital fat
Burdon, Kathryn Penelope +11 more
core +1 more source
Teprotumumab for Thyroid Eye Disease: Efficacy and Impact on Orbital Decompression Utilization
Teprotumumab has been proven effective in thyroid eye disease and associated exophthalmos management. Since its FDA approval in 2020, teprotumumab therapy has been a popular choice for managing exophthalmos which has resulted in decreased utilization of orbital decompression surgery, from 36.8% between 2015 and 2020 to 11.1% TED patients between 2020 ...
Nitish Kumar +5 more
wiley +1 more source

