Results 71 to 80 of about 8,835 (210)

PDGFRα+DPP4+ Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng   +14 more
wiley   +1 more source

Prevalence of Graves ophthalmopathy among patients with thyroid disease

open access: yesPhilippine Journal of Ophthalmology, 2010
Objective: This study determined the prevalence of Graves ophthalmopathy among thyroid-disease patients at a tertiary government hospital. Methods: Patients with thyroid disease seen at a tertiary hospital from February to September 2007 were enrolled.
Erwin D. Palisoc, MD   +2 more
doaj  

Clinical scoring scales in thyroidology: A compendium

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
This compendium brings together traditional as well as contemporary scoring and grading systems used for the screening and diagnosis of various thyroid diseases, dysfunctions, and complications. The article discusses scores used to help diagnose hypo-and
Sanjay Kalra   +2 more
doaj   +1 more source

Glymphatic System Dysfunction in Thyroid‐Associated Ophthalmopathy: A Multimodal MRI Study

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.
TAO patients exhibit impaired glymphatic function, with reduced DTI‐ALPS indices and gBOLD‐CSF coupling, but unchanged choroid plexus volume. These alterations correlate with neuropsychological symptoms and sleep disturbances. Restoring glymphatic activity may offer a therapeutic approach to enhance patient outcomes.
Lijie Zhang   +4 more
wiley   +1 more source

Biological effects of thyrotropin receptor activation on human orbital dreadipocytes [PDF]

open access: yes, 2006
purpose. Thyrotropin receptor (TSHR) expression is upregulated in the orbits of patients with Graves ophthalmopathy (GO), most of whom have TSHR-stimulating antibodies.
Baker, Glynn   +5 more
core   +1 more source

Thyroid Associated Ophthalmopathy

open access: yesDelhi Journal of Ophthalmology, 2012
Thyroid associated orbitopathy/ophthalmopathy is an autoimmune disorder. It is most prevalent among females and is usually associated with thyroid dysfunction. Clinical manifestations include soft tissue signs, lid retraction, lid lag, proptosis, restrictive myopathy, corneal exposure and optic neuropathy. Thyroid function tests, thyroid antibodies and
Sonam Angmo Bodh   +5 more
openaire   +1 more source

Issue Information

open access: yesEye &ENT Research, Volume 3, Issue 1, Page 1-4, March 2026.
No abstract is available for this article.
wiley   +1 more source

Corneal Confocal Microscopy to Diagnose Peripheral Neuropathy: A Systematic Review and Meta‐Analysis

open access: yesEuropean Journal of Neurology, Volume 32, Issue 11, November 2025.
ABSTRACT Background and Objectives Peripheral neuropathy (PN) may be diagnosed late or may remain undiagnosed. Studies have shown that measurement of corneal nerve fiber length (CNFL) using corneal confocal microscopy (CCM) may have diagnostic utility in diabetic and other peripheral neuropathies. Methods The main databases [CENTRAL, Embase (Ovid), and
Ioannis N. Petropoulos   +6 more
wiley   +1 more source

Analysis of sFas IL-6 levels in thyroid-associated ophthalmopathy: Pre- or poststeroid pulse treatment

open access: yesClinical Ophthalmology, 2008
Kimihito Maeda, Yuichiro Ohara, Masato Hashimoto, Hiroshi OhguroDepartment of Ophthalmology, Sapporo Medical University, School of Medicine, Sapporo, JapanPurpose: To investigate whether serum levels of soluble Fas (sFas) and interleukin-6 (IL-6) could ...
Kimihito Maeda   +3 more
doaj  

Double Filtration Plasmapheresis for Thyroid Storm With Encephalopathy: A Case Report

open access: yesJournal of Clinical Apheresis, Volume 40, Issue 5, October 2025.
ABSTRACT Thyroid storm is a life‐threatening endocrine emergency with a mortality rate of up to 17%. Standard treatment includes antithyroid drugs (ATD), β‐blockers, and glucocorticoids. However, some patients may require blood purification therapies, such as plasmapheresis, due to the ineffectiveness of standard treatments or contraindications like ...
Qisheng Lin   +5 more
wiley   +1 more source

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