Results 51 to 60 of about 900,918 (272)

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Metastatic Papillary Thyroid Carcinoma with Multifocal Synchronous Transformation to Anaplastic Thyroid Carcinoma

Case Reports in Pathology, 2016
Papillary thyroid carcinoma is a common malignancy to affect the thyroid and is typified by a nonaggressive nature and low rates of mortality. In contrast, anaplastic thyroid carcinoma is the most aggressive thyroid malignancy with a mortality rate of ...
Mark Benedict, Jose Costa
doaj   +1 more source

Nanoagonist‐mediated spatiotemporal reprogramming of macrophage phenotypes to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes the major molecular mechanisms governing TAM polarization and their coordinated interactions. It further highlights recent advances in nanoagonist‐based strategies that intervene in these pathways to reprogram TAMs, critically discussing their therapeutic potential, current limitations, and translational prospects.
Siqi Fang, Fengfeng Xiao, Ruie Chen, Cuixia Lu, Yi Ju, Mingqing Yuan, Yunlu Dai, Liewei Wen   +7 more
wiley   +1 more source

Bilateral Symmetry and Variation of Recurrent Laryngeal Nerve and Inferior Thyroid Artery Patterns: An Intraoperative Study of 150 Nerves

Clinical Anatomy, EarlyView.
ABSTRACT The anatomical relationship of the inferior thyroid artery (ITA) and the recurrent laryngeal nerve (RLN) is highly variable. This study aims to evaluate bilateral RLN branching patterns and their relationship to the ITA within the same patient, predicting contralateral anatomical variations and ultimately reducing intraoperative risk of RLN ...
Mark Yanni, Stavroula Mouratidou, Aleix Rovira, Ricard Simo   +3 more
wiley   +1 more source

BRAF Mutations in Papillary Thyroid Carcinoma: A Genomic Approach Using Probe-Based DNA Capture for Next-Generation Sequencing

, 2022
The BRAF V600E mutation in papillary thyroid carcinoma is the major mutation in classical subtype of papillary thyroid carcinoma and other cancers. It is the most studied predictor of clinical and pathological characteristics as well as molecular targets
Lam, AK, Smith, RA, Robert A. Smith, Alfred K. Lam   +3 more
core   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

Head &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent, Adrien Nguyen Quoc, Christine Lefevre, Laura González‐Briceño, Caroline Thalassinos, Isabelle Flechtner, Dulanjalee Kariyawasam, Yamina Dassa, Magali Viaud, Dinane Samara‐Boustani, Graziella Pinto, Hervé Monpeyssen, Sabine Sarnacki, Vincent Couloigner, Michel Polak, Athanasia Stoupa   +15 more
wiley   +1 more source

Metachronous Follicular Variant of Papillary Thyroid Microcarcinoma in a Case of Medullary Carcinoma Thyroid [PDF]

Journal of Krishna Institute of Medical Sciences University, 2016
Medullary carcinoma and papillary thyroid carcinoma arise from the different cells. Simultaneous occurrence of both types is rare. Medullary carcinomas are characterised by calcitonin positivity.
Neelam Sood, Binit Kumar Khandelia
doaj  

Immunohistochemistry on cell blocks a method for pre-operative diagnosis of papillary thyroid carcinoma by FNAC

مجلة كلية الطب, 2018
Background: Papillary thyroid carcinoma (PTC) is the commonest thyroid cancer. Cases in category- 5a of Bethesda system (suspicious for papillary carcinoma) are treated by surgical lobectomy followed by total thyroidectomy if histopathology confirms ...
Hussain A. Aljebori
doaj   +1 more source

Papillary Thyroid Carcinoma Spreading into Branchial Cleft Cyst [PDF]

, 2019
Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and it can cause cystic metastasis to the neck region. Branchial cleft cysts (BCCs) are among the most commonly encountered congenital cystic neck masses. PTC metastasis into
Yusuf Vayısoğlu, Rabia Bozdoğan Arpacı, Kemal Görür, Harun Gür, Ahmet Dağ, Onur İsmi   +5 more
core   +1 more source

Preoperative Prediction of Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma Using Arterial Enhancement Fraction Derived From Dual‐Layer Spectral CT

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the diagnostic value of arterial enhancement fraction (AEF) derived from dual‐layer detector spectral CT (DLCT) in preoperative assessment of cervical lymph node metastasis in patients with papillary thyroid carcinoma (PTC), and to compare its performance with other spectral CT quantitative parameters and conventional CT ...
Lili Ye, Xiangfa He, Ming Liang, Yuxin Wei, Hao Zhang, Xiaomin Liu, Xiaolin Zheng   +6 more
wiley   +1 more source