Atrophic hypothyroidism associated with thyrotropin receptor antibodies [PDF]
Einstein (São Paulo)Hypothyroidism is most frequently caused by Hashimoto's thyroiditis. While thyrotropin receptor antibodies are well-known in Graves’ disease-induced hyperthyroidism, their role in hypothyroidism is emerging. We report the case of a 37-year-old woman with
Marcos Tadashi Kakitani Toyoshima +5 more
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Ambient biothermal stress, preconceptional thyrotropin abnormalities, and the risk of preterm birth: a nationwide Chinese cohort study [PDF]
Nature CommunicationsEpidemiologic evidence on thermal stress and preterm birth (PTB) is based on ambient temperature rather than a biothermal metric. Thyrotropin abnormalities have been associated with PTB and may increase thermal vulnerability.
Xinghou He +18 more
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PET imaging of differentiated thyroid cancer with thyrotropin-alfa [PDF]
Scientific ReportsThyrotropin-alfa is an FDA approved recombinant human TSH agonist. This study represents a preclinical evaluation of thyrotropin-alfa as a thyroid-stimulating hormone receptor (TSHR)-targeted PET radiopharmaceutical, [89Zr]Zr-thyrotropin-alfa.
Grayson R. Gimblet +8 more
doaj +2 more sources
Resistance to thyrotropin [PDF]
Best Practice and Research in Clinical Endocrinology and Metabolism, 2017 Resistance to thyrotropin (RTSH) is broadly defined as reduced sensitivity of thyroid follicle cells to stimulation by biologically active TSH due to genetic defects. Affected individuals have elevated serum TSH in the absence of goiter, with the severity ranging from nongoitrous isolated hyperthyrotropinemia to severe congenital hypothyroidism with ...
Helmut Grasberger, Samuel Refetoff
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Role of the thyrotropin-releasing hormone of the limbic system in mood and eating regulation
Journal of Integrative Neuroscience, 2022 Thyrotropin-releasing hormone (TRH) and its receptors are expressed in the hypothalamus and limbic regions. Brain thyrotropin-releasing hormone actions are exerted directly through its receptors and indirectly by modulating the effects of ...
Elena Alvarez-Salas +3 more
doaj +1 more source
Breaking tolerance in transgenic mice expressing the human TSH receptor A-subunit: thyroiditis, epitope spreading and adjuvant as a 'double edged sword'. [PDF]
, 2012 Transgenic mice with the human thyrotropin-receptor (TSHR) A-subunit targeted to the thyroid are tolerant of the transgene. In transgenics that express low A-subunit levels (Lo-expressors), regulatory T cell (Treg) depletion using anti-CD25 before ...
Aliesky, Holly A +4 more
core +8 more sources
Thyroid Hormone Reference Intervals among Healthy Individuals In Lanzhou, China [PDF]
Endocrinology and Metabolism, 2023 Background The common reference intervals (RIs) for thyroid hormones currently used in China are provided by equipment manufacturers. This study aimed to establish thyroid hormone RIs in the population of Lanzhou, a city in the subplateau region of ...
Yan Lu +6 more
doaj +1 more source
A Multicenter, Randomized, Controlled Trial for Assessing the Usefulness of Suppressing Thyroid Stimulating Hormone Target Levels after Thyroid Lobectomy in Low to Intermediate Risk Thyroid Cancer Patients (MASTER): A Study Protocol [PDF]
Endocrinology and Metabolism, 2021 Background Postoperative thyroid stimulating hormone (TSH) suppression therapy is recommended for patients with intermediate- and high-risk differentiated thyroid cancer to prevent the recurrence of thyroid cancer.
Eun Kyung Lee +29 more
doaj +1 more source
Risk Factors for Delayed Hyperthyrotropinemia in Late Preterm Infants [PDF]
Neonatal Medicine, 2019 Purpose This study aimed to investigate the prevalence of delayed thyroid dysfunction based on iodine disinfectant use and to analyze associated risk factors.
Mun Hui Jeong +5 more
doaj +1 more source
An elevated parametric thyroid feedback quantile-based index is associated with atrial fibrillation
Frontiers in Endocrinology, 2023 IntroductionAtrial fibrillation is associated with hyperthyroidism. Within the euthyroid range, it is also associated with high thyroxine (fT4), but not with thyrotropin (TSH).
Vanesa Alonso-Ventura +36 more
doaj +1 more source