Results 131 to 140 of about 484,531 (179)
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Arginine Vasopressin as a Thyrotropin-Releasing Hormone
Science, 1987Although hypothyroidism (with concomitant increased levels of thyroid-stimulating hormone) has been associated with elevated plasma vasopressin, the role that vasopressin plays in controlling thyroid-stimulating hormone secretion from the adenohypophysis is not understood.
M D, Lumpkin, W K, Samson, S M, McCann
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1985
Although the hypothalmic control of anterior pituitary function through endogenous chemical substances was postulated more than a generation ago, not until 1955 did the search begin for the hypothalamic release-modulating substances.1 Thyrotropin-releasing hormone (TRH) (Fig.
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Although the hypothalmic control of anterior pituitary function through endogenous chemical substances was postulated more than a generation ago, not until 1955 did the search begin for the hypothalamic release-modulating substances.1 Thyrotropin-releasing hormone (TRH) (Fig.
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Thyrotropin-releasing hormone (TRH) in the cerebellum
The Cerebellum, 2007Thyrotropin-releasing hormone (TRH) was originally isolated from the hypothalamus. Besides controlling the secretion of TSH from the anterior pituitary, this tripeptide is widely distributed in the central nervous system and regarded as a neurotransmitter or modulator of neuronal activities in extrahypothalamic regions, including the cerebellum.
Nobuyuki, Shibusawa +2 more
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Thyrotropin-Releasing Hormone in the Hypothalamus of the Rat
Endocrinology, 1974The hypothalamic content of thyrotropin-releasing hormone (TRH) has been determined in normal and thyroxine-treated, thyroidectomized and hypophysectomized rats. Preliminary studies showed that hypothalamic and stalk median eminence homogenates destroyed TRH immunoreactivity, though neither was as effective as cerebral cortex in this regard ...
R M, Bassiri, R D, Utiger
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Stimulus properties of thyrotropin-releasing hormone
Psychopharmacology, 1978Male Sprague-Dawley rats were trained in a two-lever operant discrimination task using 20 mg/kg thyrotropin-releasing hormone (TRH) and saline as cues. Following completion of 40 daily training sessions, 22 of 25 subjects demonstrated a high level of discriminative responding based on the TRH and saline cues.
C N, Jones, L D, Grant, A J, Prange
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On the neuropharmacology of thyrotropin releasing hormone (TRH)
Progress in Neurobiology, 1979Abstract In this review the effects of exogenously administered TRH on behavior and other neuronally mediated phenomena in experimental animals are documented. A more cursory account of the limited neuropharmacological studies performed to date with TRH in human subjects is also provided.
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Thyroid, 1998
The peptidergic signal substance thyrotropin-releasing hormone (TRH) is inactivated by the TRH-degrading ectoenzyme (TRH-DE), a peptidase that exhibits an extraordinary high degree of substrate specificity and other unusual characteristics. There is no other ectopeptidase known capable of degrading this tripeptideamide, and vice versa, TRH is the only ...
H, Heuer, M K, Schäfer, K, Bauer
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The peptidergic signal substance thyrotropin-releasing hormone (TRH) is inactivated by the TRH-degrading ectoenzyme (TRH-DE), a peptidase that exhibits an extraordinary high degree of substrate specificity and other unusual characteristics. There is no other ectopeptidase known capable of degrading this tripeptideamide, and vice versa, TRH is the only ...
H, Heuer, M K, Schäfer, K, Bauer
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Thyrotropin-releasing hormone and thyroid hormones in amniotic fluid
American Journal of Obstetrics and Gynecology, 1979Immunoassayable TRH (iTRH) was measured in 50 amniotic fluid specimens with a mean concentration of 207 +/- 26 (SE) pg/ml. This iTRH demonstrates parallelism with the standard curve for synthetic TRH. With increasing gestational age there is an increase in iTRH levels in amniotic fluid with a decrease in 3,3',5'-triiodothyronine levels (rT3), while ...
J E, Morley +4 more
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Effect of Hypocalcemia on Hormonal Responses to Thyrotropin-Releasing Hormone
The Journal of Clinical Endocrinology & Metabolism, 1977The effects of chronic hypocalcemia on pituitary and thyroidal responses to TRH were studied in six euthyroid and three mildly hypothyroid subjects with surgical hypoparathyroidism orpseudohypoparathyroidism. In the euthyroid patients, increments in serum TSH, T3, and T4 were equal under hypocalcemic or nonnocalcemic conditions;however, a slightly but ...
H E, Carlson, A S, Brickman
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Thyrotropin Releasing Hormone: Secretion and Actions
Annual Review of Medicine, 1973Extensive physiologic and anatomic studies have demonstrated the central role of the anterior hypothalamus in the neurohumoral control of pituitary thyrotropin (TSH) secretion and biosynthesis (1, 2). The structural elucidation in 1969 of thyro tropin releasing hormone (TRH), isolated from more than 100,000 hypothalamic fragments derived from pigs (3)
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