Results 41 to 50 of about 29,678 (279)

Neonatal screening and a new cause of congenital central hypothyroidism [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2014
Congenital central hypothyroidism (C-CH) is a rare disease in which thyroid hormone deficiency is caused by insufficient thyrotropin (TSH) stimulation of a normally-located thyroid gland.
Toshihiro Tajima   +3 more
doaj   +1 more source

Orexis, Anorexia, and Thyrotropin-Releasing Hormone

open access: yesThyroid, 1998
The hypothalamus, long known to play a determinant role in food intake and satiety, has recently been shown to exert this homeostatic function via peptidergic neuronal circuits. The major peptide that has been identified as orexigenic, namely neuropeptide Y (NPY), is suppressed by leptin, an adipocyte-derived hormone, in a potential circuit that seems ...
Karydis, I, Tolis, G
openaire   +3 more sources

Linkage and association of rs3110045 and rs28499085 variants in the thyrotropin-releasing hormone receptor (TRHR) gene with the risk of familial type 2 diabetes

open access: yesAspects of Molecular Medicine
Type 2 diabetes (T2D) is a chronic and prevalent multisystemic disease that significantly increases morbidity and mortality. Dysfunction of the thyroid hormone system is common in patients with T2D, increasing their risk of both hyperthyroidism and ...
Rongling Wu, Claudia Gragnoli
doaj   +1 more source

PVN pathways controlling energy homeostasis

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Research into the control of energy balance has tended to focus on discrete brain regions, such as the brainstem, medulla, arcuate nucleus of the hypothalamus, and neocortex.
Jennifer W Hill
doaj   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

open access: yesFood Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani   +3 more
wiley   +1 more source

Physiopathological Implications of 7TM Receptors [PDF]

open access: yes, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Transcriptomic identification of starfish neuropeptide precursors yields new insights into neuropeptide evolution [PDF]

open access: yesOpen Biology, 2016
Neuropeptides are evolutionarily ancient mediators of neuronal signalling in nervous systems. With recent advances in genomics/transcriptomics, an increasingly wide range of species has become accessible for molecular analysis.
Dean C. Semmens   +5 more
doaj   +1 more source

Vitamin B12 deficiency in a pediatric patient with gastric obstruction and jejunal feeding dependence: A case report

open access: yesJPGN Reports, EarlyView.
Abstract Pediatric B12 deficiency is most caused by insufficient dietary intake, malabsorption or autoimmune gastritis. We present a unique case of B12 deficiency in a pediatric patient with complex gastrointestinal anatomy and jejunal nutritional dependence nearly two decades after unsuccessful surgical intervention.
Angela H. Nguyen   +2 more
wiley   +1 more source

Studying Periostin as a Diagnostic Marker in Sera of Iraqi Patients Hypothyroidism

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences
Hypothyroidism is one of the most common thyroid diseases in adults. Hypothyroidism is a condition that results from a deficiency of thyroid hormone and can range from being asymptomatic to life-threatening.
Duha Khalil Ibrahim, Layla Othman Farhan
doaj   +1 more source

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