Results 81 to 90 of about 29,612 (294)

Evaluating the Link Between Thyroid Function Test Results and Levothyroxine Dose in the Management of Hypothyroidism: Can We Improve Dosing Regimes?

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Over 10 million thyroid function tests (TFTs) are carried out in England each year, most requests coming from primary care. Our previous work showed that only 25% of results for patients being treated with Levothyroxine fell within the TSH/FT4 boundary circumscribing 75% of untreated individuals.
Adrian H. Heald, Lakdasa D. Premawardhana, Peter N. Taylor, Suhani Bahl, Onyebuchi E. Okosieme, Anthony A. Fryer, Antonio Bianco, Colin M. Dayan, Michael P. Stedman   +8 more
wiley   +1 more source

Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis

Epilepsia, EarlyView.
Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi, Haruka Ishibashi, Yukako Nakagami, Yoko Kobayashi Takahashi, Takato Akiba, Masaharu Miyauchi, Naohiro Yamamoto, Ryoichi Inoue, Satoshi Kodama, Takafumi Kubota, Naoto Kuroda   +10 more
wiley   +1 more source

Prodrugs of Thyrotropin-Releasing Hormone and Related Peptides as Central Nervous System Agents

Molecules, 2009
Prodrug design for brain delivery of small- and medium-sized neuropeptides was reviewed, focusing on thyrotropin-releasing hormone and structurally related peptides as examples.
Laszlo Prokai, Katalin Prokai-Tatrai
doaj   +1 more source

The syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGFβ and Activin pathways [PDF]

, 2017
IGSF1 (Immunoglobulin Superfamily 1) gene defects cause central hypothyroidism and macroorchidism. However, the pathogenic mechanisms of the disease remain unclear.
Alvarez, C.V. (Clara V.), Barrio, R. (Raquel), Cameselle-Teijeiro, J.M. (José Manuel), De Miguel, M.P. (María P.), Díaz-Rodríguez, E. (Esther), Escudero, A. (Adela), Fernández, A. (Ana), Garcia-Rendueles, A.R. (Angela R.), García, M. (Marta), García-Lavandeira, M. (Montserrat), Gorbenko del Blanco, D. (Darya), Hinkle, P.M. (Patricia M.), Hokken-Koelega, A.C.S. (Anita), Lapunzina, P. (Pablo), Matre, V. (Vilborg), Moreno, J.C. (José C.), Nevado, J. (Julián), Nistal, M. (Manuel), Rijke, Y.B. (Yolanda) de, Vallespín, E. (Elena)   +19 more
core   +2 more sources

Aвтоимун тироидит по долга употреба на агонист на гонадотропин- ослободувачки хормон како третман за предвремен централен пубертет – приказ на случај [PDF]

, 2020
There is a small number of studies that have reported abnormalities in endocrine function after a long-term gonadotropin-releasing hormone agonist (GnRHa) treatment in girls. This treatment is considered as safe and effective by most authors.
Krstevska-Konstantinova, Marina, Kuzevska-Maneva, Konstandina, Murtezani, Avdi, Tankoska, Maja   +3 more
core   +2 more sources

Unexplained Elevated Vitamin B12: Consider Macro‐B12

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Elevated vitamin B12 concentration can be caused by supplementation, liver disease, kidney disease, or myeloid malignancies. Persistent, unexplained elevations of vitamin B12 can raise concern among patients and may lead to invasive diagnostic procedures, including bone marrow biopsy.
Evelien G. E. Hurkmans, Ruben Deneer, Marten R. Nijziel, Volkher Scharnhorst   +3 more
wiley   +1 more source

The Influence of Different Light Spectra on Broiler Chicken Endocrine Systems and Productivity

Animals
In birds, light can penetrate the cranial bones and reach deep brain regions, where non-visual photoreceptors, especially in the hypothalamus, detect spectral and photoperiodic cues.
Lenuța Galan, Gheorghe Solcan, Carmen Solcan   +2 more
doaj   +1 more source

Neural differentiation of the human neuroblastoma cell line IMR32 induces production of a thyrotropin-releasing hormone-like peptide [PDF]

, 1994
The human neuroblastoma cell line IMR32 produces and secretes substantial amounts of TRH-immunoreactivity (TRH-IR) as measured with radioimmunoassay (RIA) using the nonspecific antiserum 4319.
Greef, W.J. (W.) de, Klootwijk, W. (Willem), Linkels, E., Rondeel, J.M.M. (Jan), Visser, T.J. (Theo)   +4 more
core   +1 more source

New‐Onset Psychosis in a Person with Parkinson's Disease after “Horny Goat Weed” Use

Movement Disorders Clinical Practice, EarlyView.
Juan R. Deliz, Kasra Manoocheri, Danielle N. Larson, Danny Bega   +3 more
wiley   +1 more source

Impact of glycemic variability on early detection of sudomotor dysfunction: Implications for early intervention and personalized treatment

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background This study investigates the impact of glycemic variability on sudomotor dysfunction in type 2 diabetes mellitus. Methods A total of 206 type 2 diabetes mellitus patients and 34 healthy controls were included. Sweat function (SF) was assessed using electrochemical conductance of hands (HESC) and feet (FESC).
Yang Ou, Xiao‐feng Hu, Zhi Liang, Xiao‐hui Zhang, Yi‐kun Zhou   +4 more
wiley   +1 more source