Results 81 to 90 of about 29,678 (279)

Neural differentiation of the human neuroblastoma cell line IMR32 induces production of a thyrotropin-releasing hormone-like peptide [PDF]

, 1994
The human neuroblastoma cell line IMR32 produces and secretes substantial amounts of TRH-immunoreactivity (TRH-IR) as measured with radioimmunoassay (RIA) using the nonspecific antiserum 4319.
Greef, W.J. (W.) de, Klootwijk, W. (Willem), Linkels, E., Rondeel, J.M.M. (Jan), Visser, T.J. (Theo)   +4 more
core   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Prodrugs of Thyrotropin-Releasing Hormone and Related Peptides as Central Nervous System Agents

Molecules, 2009
Prodrug design for brain delivery of small- and medium-sized neuropeptides was reviewed, focusing on thyrotropin-releasing hormone and structurally related peptides as examples.
Laszlo Prokai, Katalin Prokai-Tatrai
doaj   +1 more source

An Evaluation of Oral Subchronic Toxicity of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, Volume 46, Issue 3, Page 932-949, March 2026.
ABSTRACT Maize (Zea mays) has been consumed by humans for millennia and represents the third most abundant crop grown globally. Maize and maize‐derived products have a long history of safe consumption from bread and other cereal products in human diets worldwide. Aside from key dietary components like carbohydrates and proteins, the corn plant contains
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

The Influence of Different Light Spectra on Broiler Chicken Endocrine Systems and Productivity

Animals
In birds, light can penetrate the cranial bones and reach deep brain regions, where non-visual photoreceptors, especially in the hypothalamus, detect spectral and photoperiodic cues.
Lenuța Galan, Gheorghe Solcan, Carmen Solcan   +2 more
doaj   +1 more source

Distinct alterations of adiponectin, fibroblast growth factor 21 (FGF‐21), and insulin‐like growth factor binding protein 2 (IGFBP‐2) link dysmetabolism with cognitive decline across the Alzheimer's disease spectrum

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Metabolic disorders are risk factors for Alzheimer's disease (AD), although underlying mechanisms remain unclear. We investigated the relationship between peripheral metabolic markers – adiponectin, fibroblast growth factor 21 (FGF‐21), and insulin‐like growth factor binding protein 2 (IGFBP‐2) – and AD.
Caroline Dallaire‐Théroux, Helena L. Denis, Rosalie Cottez, Cyntia Tremblay, Amélie Provencher, Josue Valentin‐Escalera, Manon Leclerc, Andreanne Loiselle, Marine Tournissac, Olivier Potvin, Sylvie Belleville, Anne Gangloff, Frederic Picard, Henrik Zetterberg, Consortium for the Early Identification of Alzheimer's Disease – Quebec (CIMA‐Q), Frédéric Calon   +15 more
wiley   +1 more source

The 'incidentaloma' of the pituitary gland. Is neurosurgery required? [PDF]

, 1990
We describe a series of 18 patients with an intrasellar mass incidentally discovered by computed tomography or magnetic resonance imaging. The average size of the mass was 13 mm, with a range from 5 to 25 mm.
Allolio, Bruno, Menzel, Jürgen, Reincke, Martin, Saeger, Wolfgang, Winkelmann, Werner   +4 more
core   +1 more source

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi, Benedetta Massetto, Megan Fitzgerald, Kha Le, Stanley Wang, Ifong Kan‐Eng, Meenakshi Venkatraman, Naqvi Mohammad, Lawrence Blatt, Tse‐I Lin, Sushmita M. Chanda, John Fry   +11 more
wiley   +1 more source

Primary Hypothyroidism With Markedly High Prolactin

Frontiers in Endocrinology, 2016
Secondary Pituitary enlargement due to primary hypothyroidism is not a common manifestation. The loss of thyroxin feedback inhibition in primary hypothyroidism causes overproduction of thyroid-releasing hormone (TRH), which results in secondary pituitary
MOHD SALEEM ANSARI, MUSSA H. ALMALKI, MUSSA H. ALMALKI   +2 more
doaj   +1 more source

Evidence that the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in human serum may not be secreted by the pituitary gland [PDF]

, 1997
Recent studies have revealed that TRH-like immunoreactivity (TRH-LI) in human serum is predominantly pGlu-Glu-ProNH2 (< EEP-NH2), a peptide previously found in, among others tissues, the pituitary gland of various mammalian ...
Greef, W.J. de, Herder, W.W. (Wouter) de, Jong, F.H. (Frank) de, Klootwijk, W. (Willem), Lambalk, C.B. (Cornelius), Sleddens-Linkels, E. (Esther), Visser, T.J. (Theo)   +6 more
core   +1 more source