Results 91 to 100 of about 99,710 (378)
Advanced Science, EarlyView.This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang +13 more
wiley +1 more source
Luciferase activity changes during the acute period of tick-borne mixed infection in children
Бюллетень сибирской медицины, 2008 The research of clinical characteristics of different tick mixed infections etiological variants in children — tick-borne encephalitis, ixodid tick-borne borreliosis, granulocytic anaplasmosis and monocytic ehrlichiosis in human in Kemerovo region showed
O. S. Pinevich +4 more
doaj +1 more source
DomainScope: A disease network based on protein domain connections [PDF]
arXiv, 2019 Protein domains are highly conserved functional units of proteins. Because they carry functionally significant information, the majority of the coding disease variants are located on domains. Additionally, domains are specific units of the proteins that can be targeted for drug delivery purposes.
arxiv
Factors influencing the prevalence and distribution of ticks and tick- borne pathogens among domestic animals in Malaysia [PDF]
, 2016 Changes in tick-vector densities and a resultant incidence of tick-borne diseases are caused mainly by human activities affecting the environmental ecosystem, especially in tropical countries.
Lau, Seng Fong +6 more
core
Metagenomic profiling of ticks: Identification of novel rickettsial genomes and detection of tick-borne canine parvovirus [PDF]
, 2019 Background: Across the world, ticks act as vectors of human and animal pathogens. Ticks rely on bacterial endosymbionts, which often share close and complex evolutionary links with tick-borne pathogens.
Abdeen, Ziad +8 more
core +2 more sources
Advanced Science, EarlyView.Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen +12 more
wiley +1 more source
Correlation-based Discovery of Disease Patterns for Syndromic Surveillance [PDF]
arXiv, 2021 Early outbreak detection is a key aspect in the containment of infectious diseases, as it enables the identification and isolation of infected individuals before the disease can spread to a larger population. Instead of detecting unexpected increases of infections by monitoring confirmed cases, syndromic surveillance aims at the detection of cases with
arxiv
Developing a Genomic Protocol for Identification of Tick-borne Pathogens in Laikipia, Kenya [PDF]
, 2016 The region of Laikipia, Kenya, is home to a diversity of wild and domestic mammal hosts for Ixodid ticks. These tick species act as vectors for numerous infectious diseases, including economically important diseases such as East Coast fever.'Due to the ...
Lincoln, Katherine D.
core
Recent Advances in mRNA Delivery Systems for Cancer Therapy
Advanced Science, EarlyView.This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang +9 more
wiley +1 more source
Проблемы особо опасных инфекцийThe aim of the work was to compare the main socio-demographic and eco-epidemiological parameters of tick-borne viral encephalitis, tick-borne borrelioses and tick-borne rickettsiosis.Materials and methods.
O. V. Mel’nikova +3 more
doaj +1 more source