Results 91 to 100 of about 182,962 (367)

Tick-borne pathogen – Reversed and conventional discovery of disease

Frontiers in Public Health, 2014
Molecular methods have increased the number of known microorganisms associated with ticks significantly. Some of these newly identified microorganisms are readily linked to human disease while others are yet unknown to cause human disease.
Ellen eTijsse Klasen, Marion P.G. Koopmans, Hein eSprong   +2 more
doaj   +1 more source

Spatial clustering of fourteen tick species across districts of Zimbabwe

BMC Veterinary Research, 2021
Background Ticks transmit several diseases that result in high morbidity and mortality in livestock. Tick-borne diseases are an economic burden that negatively affect livestock production, cost countries billions of dollars through vaccine procurement ...
Munyaradzi Davis Shekede, Silvester Maravanyika Chikerema, Moregood Spargo, Isaiah Gwitira, Samuel Kusangaya, Aldridge Nyasha Mazhindu, Daud Nyosi Ndhlovu   +6 more
doaj   +1 more source

Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems

Advanced Healthcare Materials, EarlyView.
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei, Yannick Hajee, Gerry L. Koons, David T. Wu, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken, Mani Diba   +6 more
wiley   +1 more source

Geospatial Analysis of Rickettsial Species [PDF]

, 2019
Rickettsia species are obligate intracellular, arthropod-borne bacteria with a potential to cause multiple diseases including Rocky Mountain spotted fever (RMSF).
Frank, Amy
core   +3 more sources

Modeling the effects of variable feeding patterns of larval ticks on the transmission of Borrelia lusitaniae and Borrelia afzelii [PDF]

, 2017
Spirochetes belonging to the Borrelia burgdoferi sensu lato (sl) group cause Lyme Borreliosis (LB), which is the most commonly reported vector-borne zoonosis in Europe. B. burgdorferi sl is maintained in nature in a complex cycle involving Ixodes ricinus
Bertolotti, Luigi, Ferreri, Luca, Giacobini, Mario, Mannelli, Alessandro, Perazzo, Silvia, Venturino, Ezio   +5 more
core   +2 more sources

Linking tick and wildlife host distributions to map risk of tick-borne diseases

Parasites & Vectors
Background Tick-borne pathogens threaten livestock worldwide, causing diseases such as anaplasmosis, babesiosis, heartwater and theileriosis in cattle. The epidemiology of each disease is complex, with multiple tick and/or host species interacting across
José-María García-Carrasco, David W. Crowder, Karen C. Poh, Juan Mosqueda, Massaro W. Ueti, Javier Gutierrez-Illan   +5 more
doaj   +1 more source

Citizen science informs human-tick exposure in the Northeastern United States

International Journal of Health Geographics, 2019
Background Tick-borne disease is the result of spillover of pathogens into the human population. Traditionally, literature has focused on characterization of tick-borne disease pathogens and ticks in their sylvatic cycles.
W. Tanner Porter, Peter J. Motyka, Julie Wachara, Zachary A. Barrand, Zahraa Hmood, Marya McLaughlin, Kelsey Pemberton, Nathan C. Nieto   +7 more
doaj   +1 more source

Proteomic as an Exploratory Approach to Develop Vaccines Against Tick-Borne Diseases Using Lyme Borreliosis as a Test Case

Vaccines, 2020
Tick-borne diseases affecting humans and animals are on the rise worldwide. Vaccines constitute an effective control measure, but very few are available. We selected Lyme borreliosis, a bacterial infection transmitted by the hard tick Ixodes, to validate
Emilie Talagrand-Reboul, Benoit Westermann, Matthieu A. Raess, Gilles Schnell, Paola Cantero, Cathy Barthel, Laurence Ehret-Sabatier, Benoit Jaulhac, Nathalie Boulanger   +8 more
doaj   +1 more source

An Emerging Tick-Borne Disease of Humans Is Caused by a Subset of Strains with Conserved Genome Structure

Pathogens, 2013
The prevalence of tick-borne diseases is increasing worldwide. One such emerging disease is human anaplasmosis. The causative organism, Anaplasma phagocytophilum, is known to infect multiple animal species and cause human fatalities in the U.S., Europe ...
A. Barbet, B. Al-Khedery, S. Stuen, E. G. Granquist, R. Felsheim, U. Munderloh   +5 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source