Results 51 to 60 of about 8,483 (184)
AGRANULOCYTOSIS AND MACULOPAPULAR RASH AFTER TREATMENT WITH TICLOPIDINE – CASE REPORT
Zdravniški Vestnik, 2003 Background. Ticlopidine is one of inhibitors of platelet aggregation indicated for reducing the risk of thrombotic stroke in patients who have experienced thrombotic stroke, ischemic attacks, unstable angina pectoris, coronary artery stenting and ...
Janja Blatnik +4 more
doaj
Comparison of the Effects of Omeprazole and Rabeprazole on Ticlopidine Metabolism In Vitro
Journal of Pharmacological Sciences, 2011 .: The thienopyridine derivative ticlopidine (TCL) is an inhibitor of adenosine diphosphate-induced platelet aggregation. Combination therapy with a thienopyridine derivative and aspirin is standard after coronary stenting, although more hemorrhagic ...
Yuichi Kinoshita +9 more
doaj +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 10, Page 1695-1704, October 2025.ABSTRACT A physiologically based pharmacokinetic (PBPK) model was developed and verified for dordaviprone, a small molecule with antitumor effects in glioma patients. The model was applied to assess the drug–drug interaction (DDI) potential of dordaviprone as a victim of CYP3A4 inhibitors and inducers, and as a perpetrator of CYP3A4, CYP2C8, CYP2D6 ...
Swati Jaiswal +6 more
wiley +1 more source
Molecules, 2010 A methodological study devoted to the Mannich-like multicomponent synthesis of the antiplatelet agent (±)‑clopidogrel (7) and the ethyl ester analogue 6 is described.
Isabelle Aillaud +4 more
doaj +1 more source
Acute Iatrogenic Agranulocytosis: A Rare and Dire Case of an Adverse Drug Reaction to Be Aware
Case Reports in Hematology, 2020 Background. Iatrogenic agranulocytosis (IA), by nonchemotherapeutic drugs, is a rare adverse event, resulting in a neutrophil count under 0.5 × 109 cells/L with fever or other suggestive signs of infection. Methods.
Diogo André +5 more
doaj +1 more source
Journal of Gastroenterology and Hepatology, Volume 40, Issue 8, Page 1890-1898, August 2025.ABSTRACT Background and Aim Delayed bleeding is a major concern after gastric endoscopic submucosal dissection (ESD), especially in patients taking antithrombotic agents. The aim of this study was to evaluate the superiority of vonoprazan (VPZ) over proton pump inhibitor (PPI) in preventing delayed bleeding after gastric ESD in patients taking ...
Hiroyuki Shibata +16 more
wiley +1 more source
The Egyptian Journal of Internal Medicine, 2015 Spontaneous splenic haemorrahge and rupture is a rare but life-threatening condition requiring urgent diagnosis and treatment. Splenic haemorrhage and rupture precipitated by thrombolytic or antiocoagulant therapy has been reported frequently in the ...
Garge S Shaileshkumar +4 more
doaj +1 more source
Asian Journal of Organic Chemistry, Volume 14, Issue 7, July 2025.High‐speed flow C─H bromination with N‐bromosuccinimide (NBS) was achieved by combining a diagonal photoflow reactor (LX‐1) with a high‐power UV LED‐s (365 nm). The reaction was highly efficient with residence times in the second order range (6‐13 s). The gram‐scale synthesis of the antiplatelet agent, ticlopidine, was achieved by photoflow benzylic C ...
Takahide Fukuayma +4 more
wiley +1 more source
Exfoliative Dermatitis Due To Ticlopidine
Indian Journal of Dermatology, 2002 Rai Reena, Mukhi Sanjay V, Srinivas C.R
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PLoS ONE, 2015 There is a lack of consensus regarding which type of antiplatelet agent should be used in patients with peripheral arterial disease (PAD) and little is known on the advantages and disadvantages of dual antiplatelet therapy.
Konstantinos Katsanos +7 more
doaj +1 more source