Results 51 to 60 of about 18,009 (296)

Bivalirudin started during emergency transport for primary PCI. [PDF]

open access: yes, 2013
BACKGROUND: Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding and death in patients undergoing primary percutaneous coronary intervention (PCI).
Berg, J. van den   +25 more
core   +1 more source

Medical Adjuvant Therapy in Reducing Thrombosis With Arteriovenous Grafts and Fistulae Use: A Meta-Analysis of Randomized Controlled Trials

open access: yesClinical and Applied Thrombosis/Hemostasis, 2021
Hemodialysis is required for patients with end-stage renal disease (ESRD) that require arteriovenous (AV) grafts or fistulas for vascular access. These access points are prone to thrombosis. To determine the effect of medical adjuvant therapy on AV graft/
Kaleem Ullah MBBS   +6 more
doaj   +1 more source

Dataset of endo- and xenobiotic inhibition of CYP2B6: Comparison to CYP3A4

open access: yesData in Brief, 2022
Cytochrome P450 2B6 (CYP2B6) is a human enzyme important in chemical detoxification, steroid and fatty acid metabolism that is primarily hepatic. Therefore, induction or inhibition of CYP2B6 may perturb endo- and xenobiotic metabolism and cause adverse ...
Emily M. Olack   +2 more
doaj   +1 more source

Potent Antisickling Furaldehyde Analogs for Acute Sickle Cell Therapy: Enhanced Efficacy and Intravenous Formulation Potential

open access: yesChemMedChem, EarlyView.
This study reports novel 5‐HMF analogs with potent antisickling activities. Lead compound MMA509 enhances hemoglobin oxygen affinity and prevents erythrocyte sickling. Crystal structure of hemoglobin‐MMA509 complex explains MMA509 mechanism of action. An IV formulation is successfully developed, positioning MMA509 as a promising fast‐acting treatment ...
Abdelsattar M. Omar   +15 more
wiley   +1 more source

The importance of early diagnosis and treatment of kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon

open access: yesDermatology Practical & Conceptual, 2015
Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular tumor that may be complicated by Kasabach-Merritt phenomenon (KMP), a profound thrombocytopenia resulting from platelet trapping within a vascular tumor, either KHE or tufted angioma (
Grecia V. Vivas-Colmenares   +4 more
doaj   +1 more source

Antinuclear Antibody-Positive Ticlopidine-Induced Hepatitis

open access: yesCanadian Journal of Gastroenterology, 1996
Ticlopidine hydrochloride has been shown to reduce the risk of first or recurrent stroke in patients who have experienced a transient ischemic attack, reversible ischemic neurological deficit, recurrent stroke or first stroke. Severe liver dysfunction is
Sander Jo Veldhuyzen van Zanten   +1 more
doaj   +1 more source

ANTITHROMBOTIC THERAPY OF ISCHEMIC HEART DISEASE: FROM FAST ACTING ANTIAGGREGANTS TO STATINES AND NITRATE OXIDE. IS IT REAL?

open access: yesРациональная фармакотерапия в кардиологии, 2016
Mechanisms of atherothrombosis in atherosclerosis of coronary arteries are described. Mechanism of action and clinical efficiency of antithrombotic and antiplatelet medicines such as acetylsalicylic acid, warfarin, ticlopidine and clopidogrel are ...
I. A. Latfullin, A. A. Podolskaya
doaj   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik   +7 more
wiley   +1 more source

BUSM News and Notes [PDF]

open access: yes, 1982
Monthly newsletter providing updates of interest to the Boston University School of Medicine ...
Boston University School of Medicine Office of Informational Services
core  

Abstract [PDF]

open access: yes, 1997
Integrating the social identity and aging literatures, this work tested the hypothesis that there are two independent, but simultaneous, responses by which adults transitioning into old age can buffer themselves against age discrimination: an individual ...
Armenta, Bibiana M.   +4 more
core   +3 more sources

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