Results 161 to 170 of about 19,418 (180)

Emergence of plasmid-mediated tigecycline resistance tet(X4) gene in Enterobacterales isolated from wild animals in captivity. [PDF]

Sci One Health
Lei L, Xiong P, Yan Z, Zhang Y, Wu Y, Chen G, Song H, Zhang R.   +7 more
europepmc   +1 more source

Emergence of a novel high-level tigecycline resistance gene <i>tet</i>(X6) variant coexisting with <i>tet</i>(X2) and two <i>tet</i>(X) copies in a <i>Sphingobacterium</i> sp. [PDF]

Antimicrob Agents Chemother
Xu Q, Hou J, Schwarz S, Chai J, Lin L, Ma C, Zhu Y, Zhang W.   +7 more
europepmc   +1 more source

The ISVsa3-ORF2-abh-tet(X4) circular intermediate-mediated transmission of tigecycline resistance in Escherichia coli isolates from duck farms. [PDF]

Front Cell Infect Microbiol
Jiang C, Yang J, Xiao G, Xiao N, Hu J, Yang Y, Sun Z, Li Y.   +7 more
europepmc   +1 more source

Effects of a SigH mutation on tigecycline resistance and the SigH-RshA interaction in Mycobacteroides abscessus

George Chong, Ng Hien Fuh, Yun Fong Ngeow   +2 more
openalex   +1 more source

[Bacterial resistance and a new antibiotic: tigecycline].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2006
openaire   +1 more source

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Tigecycline–Rifampicin Restrains Resistance Development in Carbapenem-Resistant Klebsiella pneumoniae

ACS Infectious Diseases, 2023
The goal of this study was to clarify the synergistic antibacterial activity of the combination of tigecycline (TGC) and rifampicin (RIF). Additionally, the study sought to investigate the impact of this combination on the development of mutational resistance and to assess its efficacy in an in vivo model using Galleria mellonella.
Shiyi Shi, Mengxin Xu, Yining Zhao, Luozhu Feng, Qi Liu, Zhuocheng Yao, Yao Sun, Tieli Zhou, Jianzhong Ye   +8 more
openaire   +2 more sources

Development mechanism of resistant population post-exposure to tigecycline in tigecycline-heteroresistant Acinetobacter baumannii strain

International Journal of Antimicrobial Agents, 2023
Tigecycline heteroresistance is highly prevalent in Acinetobacter baumannii clinical isolates, reducing the efficacy of tigecycline treatment. This study investigated the population dynamics of A. baumannii with tigecycline heteroresistance to determine the origin of resistance that occurs over time after antibiotic exposure.
Jeongwoo Jo, Wonbeom Park, Dae-Hyuk Kweon, Kwan Soo Ko   +3 more
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The emergence of clinical resistance to tigecycline

International Journal of Antimicrobial Agents, 2013
Tigecycline (TIG) exhibits broad-spectrum activity against many Gram-positive and Gram-negative pathogens. However, clinical resistance has emerged recently and has been detected following treatment with TIG. This observation suggests that long-term monotherapy may carry a high risk for TIG resistance.
Yan, Sun, Yun, Cai, Xu, Liu, Nan, Bai, Beibei, Liang, Rui, Wang   +5 more
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RshA mutations contributing to tigecycline resistance in Mycobacteroides abscessus

Journal of Medical Microbiology, 2022
Tigecycline is an important rescue antibiotic for many bacterial infections. In Mycobacteroides abscessus , tigecycline resistance has been associated with dysregulated stress response caused by aberrations in the interaction of the SigH and RshA factors.
Kar Men Aw, Hien Fuh Ng, Col Lin Lee, Thaw Zin, Yun Fong Ngeow   +4 more
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Tigecycline therapy in pediatric patients with multidrug resistant bacteremia

Enfermedades Infecciosas y Microbiología Clínica, 2020
Multidrug resistance among bacteria increases the need for new therapeutic options. Tigecycline is one candidate drug, due to property of a wider anti-bacterial spectrum to multi-drug resistant (MDR) pathogens. However, it has still not been approved for use in pediatric patients.In this study the effectiveness and safety of tigecycline in children was
Gulhan, Belgin, Senel, EMRAH, Unal, Sevim, Tezer, Hasan, Demirtas, Gokhan, Gonulal, Deniz, Guney, Dogus, Kanik-Yuksek, Saliha, Ozkaya-Parlakay, Aslinur   +8 more
openaire   +3 more sources