Results 251 to 260 of about 301,934 (303)

The molecular structure of the tight junction

Advanced Drug Delivery Reviews, 2000
The maintenance of a barrier with controlled permeability is an important characteristic for multi-cellular organisms. In mammalian cells, the tight junction functions in that role allowing compartments with different solute composition to be separate, but not absolutely unconnected.
Lynne A Lapierre
exaly   +3 more sources

Tight junctions

Current Biology, 1998
ABSTRACT Tight junctions are the most apical intercellular junctions of epithelial and endothelial cells and create a regulatable semipermeable diffusion barrier between individual cells. On a cellular level, they form an intramembrane diffusion fence that restricts the intermixing of apical and basolateral membrane components.
Maria S, Balda, Karl, Matter
openaire   +3 more sources

The making of a tight junction

Journal of Cell Science, 1993
ABSTRACT MDCK (epithelial cells from the dog kidney) plated at confluence, establish tight junctions in 12-15 hours through a process that requires protein synthesis, formation of a ring of actin filaments in close contact with the lateral membrane of the cells, calmodulin, and a Ca2+-dependent exocytic fusion of tight junction (TJ ...
M, Cereijido   +5 more
openaire   +2 more sources

Tight junctions in the skin

Journal of Dermatological Science, 2003
Tight junctions (=zonulae occludentes, TJs) function as an effective barrier in simple epithelia. Recent developments in the molecular biology of TJs revealed that TJs also exist in the stratum granulosum and contribute to barrier function in epidermis. Furthermore, several TJ-related junctions were identified in epidermis.
Kazumasa, Morita, Yoshiki, Miyachi
openaire   +2 more sources

Epithelial Tight Junctions

American Review of Respiratory Disease, 1988
Abstract Epithelial cells differentiate by polarizing into an apical and a basolateral domain and by forming tight junctions (TJ) that control permeation through the paracellular route. The molecular nature of this structure, as well as the processes of assembly, sealing, and regulation, are not yet fully understood.
M, Cereijido   +2 more
openaire   +2 more sources

Tight junctions of oligodendrocytes

Cell and Tissue Research, 1977
Freeze-fracture replicas of the rat corpus callosum revealed prominent junctional strands in fractured cell membranes of the somata of oligodendrocytes. The junctional strands were characterized by an elaborate system of straight or slightly undulating rows of linear aggregates of particles or ridges in the P face and furrows in the E face.
E, Tani, T, Itagaki, M, Nakano
openaire   +2 more sources

On tight-junction structure

Cell, 1982
We have analyzed previous thin-section and freeze-fracture observations of the tight junction. We propose that the tight-junction strands represent intramembranous, cylindrical, inverted micelles. At the junctional site, the exoplasmic halves of the plasma membranes are fused into a continuous leaflet.
P, Pinto da Silva, B, Kachar
openaire   +2 more sources

Home - About - Disclaimer - Privacy