Results 131 to 140 of about 101,827 (258)

Tricellulin regulates the tight junctions and cytoskeleton of pancreatic acinar cells through the NF-κB pathway in hypertriglyceridemic acute pancreatitis. [PDF]

Biomed Rep
Wei G, Liang Z, Wei H, Wu Q, Wang J, Lin L, Liang Z, Yang H, Qin M.   +8 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Tight junctions expression is affected by active, inactive, and derivatives of <i>Akkermansia muciniphila</i>. [PDF]

Iran J Microbiol
Ghaderi F, Hajebrahimi Z, Fateh A, Sotoodehnejadnematalahi F, Ahmadi Badi S, Vaezijoze S, Siadat SD.   +6 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Roles of protein-protein interactions and monolayer mechanics in tricellulin localization to tricellular tight junctions. [PDF]

Biol Open
Mushtaq T, Lehtimäki J, Kogan K, Peränen J, Liu X, Varjosalo M, Manninen A, Lappalainen P.   +7 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Multi-Strain Probiotic and Bee Pollen Supplementation Attenuates CCl₄-Induced Altered Intestinal Tight Junctions in Rodents. [PDF]

Curr Issues Mol Biol
Alsayari N, Bhat RS, Zargar S, Aldbass AM, Al-Daihan S.   +4 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Safe focused ultrasound-mediated blood-brain barrier opening is driven primarily by transient reorganization of tight junctions. [PDF]

Commun Eng
Noel RL, Kugelman T, Karakatsani ME, Shahriar S, Willner MJ, Jimenez DA, Choi CS, Nimi Y, Ji R, Agalliu D, Konofagou EE.   +10 more
europepmc   +1 more source