Results 21 to 30 of about 101,827 (258)

Effects of acute and chronic disease on cell junctions in mouse liver

EXCLI Journal : Experimental and Clinical Sciences, 2023
Cell junctions, including anchoring, occluding and communicating junctions, play an indispensable role in tissue architecture and homeostasis. Consequently, malfunctioning of cell junctions is linked with a wide range of disorders, including in liver ...
Raf Van Campenhout, Bruno Cogliati, Mathieu Vinken   +2 more
doaj   +1 more source

COMPARATIVE ANALYSIS OF TIGHT JUNCTIONS OF EPITHELIUM OF RATS JEJUNUM UNDER THE EFFECT OF LIPOPOLYSACCHARIDE AND CHOLERA TOXIN

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Comparative study of tight junctions and ultrastructure alterations of enterocytes of mucous membranes of jejunum of rats under the effect of lipopolysaccharides and cholera toxin. Materials and methods.
O. N. Vishnevskaya, O. V. Rybalchenko, I. V. Larionov, O. G. Orlova, A. G. Markov   +4 more
doaj   +1 more source

Loss of Endothelial Barrier Function in the Inflammatory Setting: Indication for a Cytokine-Mediated Post-Transcriptional Mechanism by Virtue of Upregulation of miRNAs miR-29a-3p, miR-29b-3p, and miR-155-5p

Cells, 2021
Dysfunction of the endothelial barrier plays a central role in the pathogenesis of both acute and chronic inflammatory processes such as sepsis or atherosclerosis.
Daniel Maucher, Birte Schmidt, Julia Schumann   +2 more
doaj   +1 more source

ZO-1 Guides Tight Junction Assembly and Epithelial Morphogenesis via Cytoskeletal Tension-Dependent and -Independent Functions

Cells, 2022
Formation and maintenance of tissue barriers require the coordination of cell mechanics and cell–cell junction assembly. Here, we combined methods to modulate ECM stiffness and to measure mechanical forces on adhesion complexes to investigate how tight ...
Alexis J. Haas, Ceniz Zihni, Susanne M. Krug, Riccardo Maraspini, Tetsuhisa Otani, Mikio Furuse, Alf Honigmann, Maria S. Balda, Karl Matter   +8 more
doaj   +1 more source

The mechanobiology of tight junctions [PDF]

Biophysical Reviews, 2019
Tight junctions (TJ) play a central role in the homeostasis of epithelial and endothelial tissues, by providing a semipermeable barrier to ions and solutes, by contributing to the maintenance of cell polarity, and by functioning as signaling platforms.
openaire   +3 more sources

Structural dynamics of tight junctions modulate the properties of the epithelial barrier.

PLoS ONE, 2019
Tight junctions are dynamic structures that are crucial in establishing the diffusion and electrical barrier of epithelial monolayers. Dysfunctions in the tight junctions can impede this barrier function and lead to many pathological conditions ...
Aapo Tervonen, Teemu O Ihalainen, Soile Nymark, Jari Hyttinen   +3 more
doaj   +1 more source

Disruption of Claudin-Made Tight Junction Barriers by Clostridium perfringens Enterotoxin: Insights from Structural Biology

Cells, 2022
Claudins are a family of integral membrane proteins that enable epithelial cell/cell interactions by localizing to and driving the formation of tight junctions.
Chinemerem P. Ogbu, Sourav Roy, Alex J. Vecchio   +2 more
doaj   +1 more source

The ACE2 Receptor for Coronavirus Entry Is Localized at Apical Cell—Cell Junctions of Epithelial Cells

Cells, 2022
Transmembrane proteins of adherens and tight junctions are known targets for viruses and bacterial toxins. The coronavirus receptor ACE2 has been localized at the apical surface of epithelial cells, but it is not clear whether ACE2 is localized at apical
Florian Rouaud, Isabelle Méan, Sandra Citi   +2 more
doaj   +1 more source

Listeria monocytogenes invades the epithelial junctions at sites of cell extrusion. [PDF]

PLoS Pathogens, 2006
Listeria monocytogenes causes invasive disease by crossing the intestinal epithelial barrier. This process depends on the interaction between the bacterial surface protein Internalin A and the host protein E-cadherin, located below the epithelial tight ...
Mickey Pentecost, Glen Otto, Julie A Theriot, Manuel R Amieva   +3 more
doaj   +2 more sources

Cell–Cell Interaction Proteins (Gap Junctions, Tight Junctions, and Desmosomes) and Water Transporter Aquaporin 4 in Meningothelial Cells of the Human Optic Nerve

Frontiers in Neurology, 2017
PurposeMeningothelial cells (MECs) play a central role in the maintenance of cerebrospinal fluid (CSF) homeostasis and in physiological and pathophysiological processes within the subarachnoid space (SAS) linking them to optic nerve (ON) pathologies ...
Thi Ngoc Co Zeleny, Corina Kohler, Corina Kohler, Albert Neutzner, Albert Neutzner, Hanspeter E. Killer, Hanspeter E. Killer, Peter Meyer, Peter Meyer   +8 more
doaj   +1 more source