Results 11 to 20 of about 198,554 (196)
Tight Junctions as Targets and Effectors of Mucosal Immune HomeostasisSummary
Cellular and Molecular Gastroenterology and Hepatology, 2020 Defective epithelial barrier function is present in maladies including epidermal burn injury, environmental lung damage, renal tubular disease, and a range of immune-mediated and infectious intestinal disorders. When the epithelial surface is intact, the
Li Zuo, Wei-Ting Kuo, Jerrold R. Turner
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Frontiers in Neurology, 2023 IntroductionThe movement of fluids and solutes across the ependymal barrier, and their changes in physiologic and disease states are poorly understood.
Riccardo Serra +3 more
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Tight junctions at a glance [PDF]
Journal of Cell Science, 2008 Tight junctions (TJs) are morphologically distinct and highly regulated areas of close contact between the plasma membranes of neighbouring epithelial and endothelial cells. They are the most apical component of the epithelial junctional complex (which also includes adherens junctions and ...
Maria S, Balda, Karl, Matter
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FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes. [PDF]
PLoS ONE, 2013 Proper development and tissue maintenance requires cell-cell adhesion structures, which serve diverse and crucial roles in tissue morphogenesis. Epithelial tissues have three main types of cell-cell junctions: tight junctions, which play a major role in ...
Henry P Foote +2 more
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Frontiers in Allergy, 2022 Allergic rhinitis is one of the most common diseases, which is caused by IgE-mediated reactions to inhaled allergens. Essential oils from the Mentha piperita leaf (EOM) are known to be effective for various diseases, such as respiratory diseases. However,
Nayoung Park +3 more
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α5 integrin regulates hepatic tight junctions through SRC-TET1-mediated DNA hydroxymethylation
iScience, 2022 Summary: The functional tight junctions’ integrity plays an important role in liver physiology. A variety of liver diseases have been associated with the perturbation of tight junctions.
Yuejiao Ma +7 more
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Keratin 76 is required for tight junction function and maintenance of the skin barrier. [PDF]
PLoS Genetics, 2014 Keratins are cytoskeletal intermediate filament proteins that are increasingly being recognised for their diverse cellular functions. Here we report the consequences of germ line inactivation of Keratin 76 (Krt76) in mice.
Tia DiTommaso +6 more
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Claudins in the Renal Collecting Duct [PDF]
, 2019 The renal collecting duct fine-tunes urinary composition, and thereby, coordinates key physiological processes, such as volume/blood pressure regulation, electrolyte-free water reabsorption, and acid-base homeostasis.
Leiz, Janna, Schmitt-Ott, Kai M.
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Biomolecules, 2021 We previously demonstrated that the bile acid taurocholic acid (TCA) inhibits features of age-related macular degeneration (AMD) in vitro. The purpose of this study was to determine if the glycine-conjugated bile acids glycocholic acid (GCA ...
Cassandra Warden, Milam A. Brantley
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The multifarious regulation of the apical junctional complex [PDF]
Open Biology, 2020 Epithelial cells form highly organized polarized sheets with characteristic cell morphologies and tissue architecture. Cell–cell adhesion and intercellular communication are prerequisites of such cohesive sheets of cells, and cell connectivity is ...
Alexandra D. Rusu, Marios Georgiou
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