Results 11 to 20 of about 101,827 (258)

FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes. [PDF]

open access: yesPLoS ONE, 2013
Proper development and tissue maintenance requires cell-cell adhesion structures, which serve diverse and crucial roles in tissue morphogenesis. Epithelial tissues have three main types of cell-cell junctions: tight junctions, which play a major role in ...
Henry P Foote   +2 more
doaj   +1 more source

Adherens, tight, and gap junctions in ependymal cells: A systematic review of their contribution to CSF-brain barrier

open access: yesFrontiers in Neurology, 2023
IntroductionThe movement of fluids and solutes across the ependymal barrier, and their changes in physiologic and disease states are poorly understood.
Riccardo Serra   +3 more
doaj   +1 more source

Protective effects of inhalation of essential oils from Mentha piperita leaf on tight junctions and inflammation in allergic rhinitis

open access: yesFrontiers in Allergy, 2022
Allergic rhinitis is one of the most common diseases, which is caused by IgE-mediated reactions to inhaled allergens. Essential oils from the Mentha piperita leaf (EOM) are known to be effective for various diseases, such as respiratory diseases. However,
Nayoung Park   +3 more
doaj   +1 more source

α5 integrin regulates hepatic tight junctions through SRC-TET1-mediated DNA hydroxymethylation

open access: yesiScience, 2022
Summary: The functional tight junctions’ integrity plays an important role in liver physiology. A variety of liver diseases have been associated with the perturbation of tight junctions.
Yuejiao Ma   +7 more
doaj   +1 more source

Keratin 76 is required for tight junction function and maintenance of the skin barrier. [PDF]

open access: yesPLoS Genetics, 2014
Keratins are cytoskeletal intermediate filament proteins that are increasingly being recognised for their diverse cellular functions. Here we report the consequences of germ line inactivation of Keratin 76 (Krt76) in mice.
Tia DiTommaso   +6 more
doaj   +1 more source

Glycine-Conjugated Bile Acids Protect RPE Tight Junctions against Oxidative Stress and Inhibit Choroidal Endothelial Cell Angiogenesis In Vitro

open access: yesBiomolecules, 2021
We previously demonstrated that the bile acid taurocholic acid (TCA) inhibits features of age-related macular degeneration (AMD) in vitro. The purpose of this study was to determine if the glycine-conjugated bile acids glycocholic acid (GCA ...
Cassandra Warden, Milam A. Brantley
doaj   +1 more source

The multifarious regulation of the apical junctional complex [PDF]

open access: yesOpen Biology, 2020
Epithelial cells form highly organized polarized sheets with characteristic cell morphologies and tissue architecture. Cell–cell adhesion and intercellular communication are prerequisites of such cohesive sheets of cells, and cell connectivity is ...
Alexandra D. Rusu, Marios Georgiou
doaj   +1 more source

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family

open access: yesBMC Cell Biology, 2009
Background Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge.
Balda Maria S   +3 more
doaj   +1 more source

Tight Junctions of the Neurovascular Unit

open access: yesFrontiers in Molecular Neuroscience, 2021
The homeostatic balance of the brain and retina is maintained by the presence of the blood-brain and inner blood-retinal barrier (BBB/iBRB, respectively) which are highly specialized barriers.
Natalie Hudson, Matthew Campbell
doaj   +1 more source

Tight junction proteins

open access: yesProgress in Biophysics and Molecular Biology, 2003
A fundamental function of epithelia and endothelia is to separate different compartments within the organism and to regulate the exchange of substances between them. The tight junction (TJ) constitutes the barrier both to the passage of ions and molecules through the paracellular pathway and to the movement of proteins and lipids between the apical and
L, González-Mariscal   +3 more
openaire   +2 more sources

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