Results 11 to 20 of about 412,031 (297)
Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family [PDF]
BMC Cell Biology, 2009 Background Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge.
Balda Maria S +3 more
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Tight Junctions of the Neurovascular Unit [PDF]
Frontiers in Molecular Neuroscience, 2021 The homeostatic balance of the brain and retina is maintained by the presence of the blood-brain and inner blood-retinal barrier (BBB/iBRB, respectively) which are highly specialized barriers.
Natalie Hudson, Matthew Campbell
doaj +5 more sources
Structural organization of the tight junctions [PDF]
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2008 Tight junctions are the most apical organelle of the apical junctional complex and are primarily involved in the regulation of paracellular permeability and membrane polarity. Extensive research in the past two decades has identified not only the individual molecules of the tight junctions but also their mutual interactions, which are the focus of the ...
Paris, Luca +3 more
openaire +3 more sources
Tight junctions at a glance [PDF]
Journal of Cell Science, 2008 Tight junctions (TJs) are morphologically distinct and highly regulated areas of close contact between the plasma membranes of neighbouring epithelial and endothelial cells. They are the most apical component of the epithelial junctional complex (which also includes adherens junctions and ...
Maria S, Balda, Karl, Matter
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Brain barriers: Crosstalk between complex tight junctions and adherens junctions [PDF]
, 2015 Unique intercellular junctional complexes between the central nervous system (CNS) microvascular endothelial cells and the choroid plexus epithelial cells form the endothelial blood-brain barrier (BBB) and the epithelial blood-cerebrospinal fluid barrier
Tietz, Silvia +3 more
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α5 integrin regulates hepatic tight junctions through SRC-TET1-mediated DNA hydroxymethylation
iScience, 2022 Summary: The functional tight junctions’ integrity plays an important role in liver physiology. A variety of liver diseases have been associated with the perturbation of tight junctions.
Yuejiao Ma +7 more
doaj +1 more source
Keratin 76 is required for tight junction function and maintenance of the skin barrier. [PDF]
PLoS Genetics, 2014 Keratins are cytoskeletal intermediate filament proteins that are increasingly being recognised for their diverse cellular functions. Here we report the consequences of germ line inactivation of Keratin 76 (Krt76) in mice.
Tia DiTommaso +6 more
doaj +1 more source
Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2 [PDF]
, 2007 Background: Tight junctions are required for epithelial barrier formation and participate in the regulation of signalling mechanisms that control proliferation and differentiation.
Aijaz Saima +7 more
core +1 more source
Biomolecules, 2021 We previously demonstrated that the bile acid taurocholic acid (TCA) inhibits features of age-related macular degeneration (AMD) in vitro. The purpose of this study was to determine if the glycine-conjugated bile acids glycocholic acid (GCA ...
Cassandra Warden, Milam A. Brantley
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The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density [PDF]
, 2003 Epithelial tight junctions regulate paracellular permeability, restrict apical/basolateral intramembrane diffusion of lipids, and have been proposed to participate in the control of epithelial cell proliferation and differentiation.
Balda, MS +5 more
core +1 more source