Results 41 to 50 of about 198,554 (196)
Frontiers in Neurology, 2017 PurposeMeningothelial cells (MECs) play a central role in the maintenance of cerebrospinal fluid (CSF) homeostasis and in physiological and pathophysiological processes within the subarachnoid space (SAS) linking them to optic nerve (ON) pathologies ...
Thi Ngoc Co Zeleny +8 more
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Gut Pathogens, 2019 Campylobacter jejuni secretes HtrA (high temperature requirement protein A), a serine protease that is involved in virulence. Here, we investigated the interaction of HtrA with the host protein occludin, a tight junction strand component ...
Aileen Harrer +7 more
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YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation. [PDF]
PLoS ONE, 2012 Tissue development and organ growth require constant remodeling of cell-cell contacts formed between epithelial cells. The Hippo signaling cascade curtails organ growth by excluding the transcriptional co-activator Yes Associated Protein 1 (YAP1) from ...
Kassiani Skouloudaki, Gerd Walz
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Modulation of Intestinal Epithelial Permeability via Protease-Activated Receptor-2-Induced Autophagy
Cells, 2022 Protease-activated receptor 2 (PAR2) alleviates intestinal inflammation by upregulating autophagy. PAR2 also modulates tight junctions through β-arrestin signaling.
Yuju Kim +7 more
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Tight junctions: Closing in on the seal [PDF]
Current Biology, 1999 The claudins have recently been identified as a large family of transmembrane proteins located at tight junctions between epithelial cells; they create the paracellular diffusion barrier and, surprisingly, may also confer channel-like selectivity for passage of solutes through the tissue barrier.
Anderson, James Melvin +1 more
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Frontiers in OncologyEndothelial cells lining the vessel wall are connected by adherent, tight and gap junctions. Adherent junctions are common to all endothelial cells, whereas tight and gap junctions graduate within different vascular segments.
Domenico Ribatti
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BMC Cell Biology, 2010 Background Endothelial tight and adherens junctions control a variety of physiological processes like adhesion, paracellular transport of solutes or trafficking of activated leukocytes. Formation and maintenance of endothelial junctions largely depend on
Beese Michaela +3 more
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Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling [PDF]
, 2012 The functions of many organs depend on the generation of an epithelium. The transition from a set of loosely connected nonpolarized cells to organized sheets of closely associated polarized epithelial cells requires the assembly of specialized cell ...
Pieters, Tim +2 more
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Tight Junctions in Cell Proliferation [PDF]
International Journal of Molecular Sciences, 2019 Tight junction (TJ) proteins form a continuous intercellular network creating a barrier with selective regulation of water, ion, and solutes across endothelial, epithelial, and glial tissues. TJ proteins include the claudin family that confers barrier properties, members of the MARVEL family that contribute to barrier regulation, and JAM molecules ...
Mónica Díaz-Coránguez +2 more
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Biology Open, 2019 Tight junctions prevent paracellular flow and maintain cell polarity in an epithelium. These junctions are also required for maintaining the blood-testis barrier, which is essential for sperm differentiation.
Pankaj Dubey +4 more
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