Results 91 to 100 of about 7,983,498 (338)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Communication system features dual mode range acquisition plus time delay measurement [PDF]
, 1968 Communication system combines range acquisition system and time measurement system for tracking high velocity aircraft and spacecraft. The range acquisition system uses a pseudonoise code to determine range and the time measurement system reduces ...
Atwood, S. W. +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On the Positive Effect of Delay on the Rate of Convergence of a Class of Linear Time-Delayed Systems
, 2019 This paper is a comprehensive study of a long observed phenomenon of increase in the stability margin and so the rate of convergence of a class of linear systems due to time delay.
Kia, Solmaz S., Moradian, Hossein
core +1 more source
Control of unstable steady states in neutral time-delayed systems
, 2008 We present an analysis of time-delayed feedback control used to stabilize an unstable steady state of a neutral delay differential equation. Stability of the controlled system is addressed by studying the eigenvalue spectrum of a corresponding ...
Blyuss, K. B. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Finite-Time Stability of a Time-Delay Fractional-Order Hydraulic Turbine Regulating System
IEEE Access, 2019 Finite-time terminal sliding mode control of a time-delay fractional-order hydraulic turbine regulating system (HTRS) is studied. First, an improved Adams-Bashforth-Moulton algorithm is introduced to solve the fractional-order nonlinear system with a ...
Peng Chen +3 more
doaj +1 more source
Adaptive neural network prescribed performance control for dual switching nonlinear time-delay system. [PDF]
Sci Rep, 2023 Mu Q, Long F, Li B.
europepmc +1 more source