Results 91 to 100 of about 1,009,169 (294)
Two-photon excitation spectroscopy of 1,5--Diphenyl-1,3,5-hexatriene using phase modulation
, 2018 We have used two-photon Fourier transform spectroscopy to investigate the first singlet excited state (S1) of a prototypical polyene molecule 1,5 -- Diphenyl-1,3,5-hexatriene.
Karki, Khadga Jung, Kumar, Pushpendra
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Controller performance design and assessment using nonlinear generalized minimum variance benchmark : scalar case [PDF]
, 2004 A nonlinear version of the Generalized Minimum Variance (GMV) multivariable control law has been recently derived for the control of nonlinear, possibly time-varying systems.
Grimble, M.J., Majecki, P.M.
core
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
IEEE Access, 2019 Time-varying disturbances not only exist in the external delay of Markovian jump system but also may exist in the transfer rate of internal probability transfer.
Liankun Sun, Nuo Xu
doaj +1 more source
Delay‐Independent Stability of Switched Linear Systems withUnbounded Time‐Varying Delays [PDF]
Abstract and Applied Analysis, 2012 This paper is focused on delay‐independent stability analysis for a class of switched linear systems with time‐varying delays that can be unbounded. When the switched system is not necessarily positive, we first establish a delay‐independent stability criterion under arbitrary switching signal by using a new method that is different from the methods to
openaire +4 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Stabilization of linear continuous time-varying systems with state delays in Hilbert spaces
Electronic Journal of Differential Equations, 2001 This paper studies the stabilization of the infinite-dimensional linear time-varying system with state delays $$dot x = A(t)x + A_1(t)x(t-h)+B(t)u,.$$ The operator $A(t)$ is assumed to be the generator of a strong evolution operator.
Vu Ngoc Phat
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source