Results 141 to 150 of about 153,320 (330)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Constrained Weighted Least-Squares Algorithms for 3-D AOA-Based Hybrid Localization
IEEE Open Journal of Signal ProcessingSource localization with time-of-arrival (TOA), time-difference-of-arrival (TDOA), time-delay (TD), received-signal-strength (RSS), or angle-of-arrival (AOA) measurements from several spatially distributed sensors is commonly used in practice.
Yanbin Zou +3 more
doaj +1 more source
Underwater Acoustic Source Seeking Using Time-Difference-of-Arrival Measurements
The research presented in this paper is aimed at developing a control algorithm for an autonomous surface system carrying a two-sensor array consisting of two acoustic receivers, capable of measuring the time-difference-of-arrival (TDOA) of a ...
Lončar, Ivan +2 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 2019 In allusion to fault location failure on wide area travelling-wave-based fault location methods caused by the indeterminate shortest transmission path of initial travelling wave and the inaccurate travelling wave velocity, this study proposed a novel ...
Yilin Li, Rui Chen, Xianggen Yin
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Positioning using time-difference of arrival measurements
, 2003 The problem of position estimation from Time Difference Of Arrival (TDOA) measurements occurs in a range of applications from wireless communication networks to electronic warfare positioning.
Fredrik Gustafsson, Fredrik Gunnarsson
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
EdgeTDC: On the Security of Time Difference of Arrival Measurements in CAN Bus Systems
, 2023 Marc Roeschlin +4 more
openalex +2 more sources
Node localisation in mobile ad hoc networks using double time difference of arrival
, 2009 The double time difference of arrival (DTDOA) approach applying in the mobile ad hoc network can effective avoid the synchronization problem. This paper investigates the performance of techniques for DTDOA node localisation in Mobile ad hoc network by ...
Marek Bialkowski +7 more
core +1 more source