Results 121 to 130 of about 6,922,047 (309)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Effects of Boundary Condition Models on the Seismic Responses of a Container Crane

open access: yesApplied Sciences, 2019
In recent years, several large earthquakes have caused the collapse of container cranes, which have resulted in halting of freighting, and significantly affected the economy.
Jungwon Huh   +4 more
doaj   +1 more source

Analysis of The Black Fairy by Fenton Johnson [PDF]

open access: yes, 2012
This essay examines a rare early twentieth-century children’s story about and geared towards African Americans: “The Black Fairy” by Fenton Johnson. “The Black Fairy” was published in The Upward Path (1920), an anthology designed as a “Reader for Colored
Tolbert, Crystal
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Seismic response of concrete gravity dam reinforced with FRP sheets on dam surface

open access: yesWater Science and Engineering, 2013
This paper aims at exploring the effects of anti-seismic reinforcement with the fiber-reinforced polymer (FRP) material bonded to the dam surface in dam engineering. Time-history analysis was performed to simulate the seismic failure process of a gravity
Hong Zhong, Na-li Wang, Gao Lin
doaj   +1 more source

Cosmology of F(R) nonlinear massive gravity

open access: yes, 2014
The theory of nonlinear massive gravity can be extended into the F(R) form as developed in Phys.Rev.D90, 064051 (2014). Being free of the Boulware-Deser ghost, such a construction has the additional advantage of exhibiting no linear instabilities around ...
Cai, Yi-Fu, Saridakis, Emmanuel N.
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time-History Analysis of Frictionally Damped Structures

open access: yes, 2011
During major seismic actions, a significant amount of energy is induced to structures. The means by which this energy is dissipated, determines the level of structural degradation. Special emphasis is placed on avoiding loss of human lives due to the earthquake action.
Ştefancu, Andrei-Ionuţ   +2 more
openaire   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Studi Perbandingan Analisis Statik dan Dinamik pada Girder Kereta Cepat

open access: yesJurnal Teknik Sipil
Faktor perbesaran dinamis (dynamic amplification factor – DMF) lazim digunakan oleh perencana untuk memperbesar respons struktur (gaya dalam, perpindahan) yang didapatkan dari analisi statis untuk mengakomodasi efek dinamis dari laju kendaraan.
Erwin Lim   +3 more
doaj   +1 more source

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