Results 71 to 80 of about 197,559 (299)
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Complete and Compact 32-Channel System for Time-Correlated Single-Photon Counting Measurements
Single-photon detectors play a key role in many research fields such as biology, chemistry, medicine, and space technology, and in recent years, single-photon avalanche diodes (SPADs) have become a valid alternative to photo multiplier tubes (PMTs ...
A. Cuccato +6 more
doaj +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Low-Power Wide-Range Time-to-Digital Converter for Time-of-Flight Range Finders
Time-to-digital Converters (TDCs) are increasingly considered to offer low complexity and scaling-friendly implementations in embedded applications, replacing voltage-domain analog-to-digital converters (ADCs).
Ahmed M. Mohey +3 more
doaj +1 more source
Design of a compact and low-power TDC for an array of SiPM's in 110nm CIS technology [PDF]
Silicon photomultipliers (SiPMs) are meant to substitute photomultiplier tubes in high-energy physics detectors and nuclear medicine. This is because of their -to name a few interesting properties- compactness, lower bias voltage, tolerance to magnetic ...
Bandi, Franco +3 more
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
The upgrade of the ATLAS muon spectrometer for high-luminosity LHC requires new trigger and readout electronics for the various elements of the detector.
An, Qi +8 more
core +1 more source
Adaptive High-Bandwidth Digitally Controlled Buck Converter with Improved Line and Load Transient Response [PDF]
Digitally controlled switching converter suffers from bandwidth limitation because of the additional phase delay in the digital feedback control loop. In order to overcome the bandwidth limitation without using a high sampling rate, this paper presents ...
Chan, PCH, Lee, ATL, Sin, JKO
core +1 more source

