Results 81 to 90 of about 19,050,909 (270)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Polychlorinated naphthalenes in UK soils: time trends, source markers and equilibrium status. [PDF]
, 2001 Polychlorinated naphthalenes (PCNs) have been analyzed in archived soil from the U.K. to investigate historical trends. Samples were obtained from the Broadbalk experiment plots (1944−1986) and Luddington experiment station (1968−1990).
Helm, Paul +11 more
core
Journal of Veterinary ResearchPolychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDFs) and polychlorinated biphenyls (PCBs) are a group of undesirable chemical substances classified as persistent organic pollutants (POPs).
Pajurek Marek +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Trends in the Disease Burden and Risk Factors of Women’s Cancers in China From 1990 to 2019
International Journal of Public HealthObjectivesTo examine age-specific trends and risk factors in the burden of women’s cancers (WCs) in China from 1990 to 2019 to inform strategies.MethodsData were sourced from the Global Burden of Disease 2019 and World Population Prospects 2019.
Wei Ning +6 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
, 2018 Google Trends time series on which analyses in Tran et al. (2017), published in PLOS ONE, were based on.
Ulrich Tran (629444) +5 more
core +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground In the wake of pandemic‐related health decline and health care disruptions, there are concerns that previous gains for cardiovascular risk factors may have stalled or reversed.
Amy Y. X. Yu +13 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prevalence and Incidence Rates of Atrial Fibrillation in Denmark 2004–2018
Clinical Epidemiology, 2022 Emilie R Hegelund,1,2 Lars J Kjerpeseth,3 Laust H Mortensen,1,2 Jannicke Igland,4 Trygve Berge,5 Mariam Anjum,3,5 Grethe S Tell,4 Inger Ariansen3 1Methodology and Analysis, Statistics Denmark, Copenhagen, Denmark; 2Department of Public Health, University
Hegelund ER +7 more
doaj