Results 101 to 110 of about 2,029,326 (338)

Developmental time windows for axon growth influence neuronal network topology

, 2015
Early brain connectivity development consists of multiple stages: birth of neurons, their migration and the subsequent growth of axons and dendrites.
Kaiser, Marcus, Lim, Sol
core   +1 more source

Biomaterials to Neuroprotect the Stroke Brain: A Large Opportunity for Narrow Time Windows [PDF]

, 2020
Daniel González‐Nieto, Rocío Fernández-Serra, José Pérez‐Rigueiro, Fivos Panetsos, Ricardo Martı́nez-Murillo, Gustavo V. Guinea   +5 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Perbandingan Metode Round Trip Time & Vehicle Routing Problem Time Windows Dalam Pemilihan Supply Point Pada Proses Distribusi Pertashop

, 2022
Dwi Nurma Heitasari, Muhammad Kemal Ghifari   +1 more
openalex   +2 more sources

The three second time window in poems and language processing in general: Complementarity of discrete timing and temporal continuity [PDF]

, 2020
Xinchi Yu, Yan Bao
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

An Improved Iterated Greedy Algorithm for Solving Collaborative Helicopter Rescue Routing Problem with Time Window and Limited Survival Time

Algorithms
Research on helicopter dispatching has received considerable attention, particularly in relation to post-disaster rescue operations. The survival chances of individuals trapped in emergency situations decrease as time passes, making timely helicopter ...
Xining Cui, Kaidong Yang, Xiaoqing Wang, Peng Duan   +3 more
doaj   +1 more source

Metamaterial window glass for adaptable energy efficiency [PDF]

, 2014
textA computational analysis of a metamaterial window design is presented for the purpose of increasing the energy efficiency of buildings in seasonal or cold climates.
Mann, Tyler Pearce
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source