Effects of timolol maleate eye drops on experimentally dilated cardiomyopathy and healthy rabbits [PDF]
Open Veterinary Journal, 2021 Background: Dilated cardiomyopathy (DCM) is the most frequently diagnosed cardiomyopathy in rabbits. Timolol maleate (nonselective beta-blockers), which reduces the heart rate (HR) and blood pressure, has been used for glaucoma.
Mitsuhiro Isaka +3 more
doaj +2 more sources
Topical timolol maleate 0.5% after fractional carbon dioxide laser versus fractional carbon dioxide laser alone in treatment of acne scars: split face comparative study [PDF]
Scientific Reports, 2023 Acne is a common inflammatory condition that mostly involves the face, chest and back. A number of different modalities had been employed for treating scars of which laser remains to be a pivotal choice.
Aya Reda Mohamed Hawwas +3 more
doaj +2 more sources
Prolonged central nervous system and respiratory depression in preterm neonates after exposure to brimonidine tartrate and timolol maleate ophthalmic drops [PDF]
GMS Ophthalmology Cases, 2020 Objective: We report three cases of preterm neonates who presented with central nervous system (CNS) and respiratory depression after inadvertent exposure to brimonidine tartrate 0.2% and timolol maleate 0.5% fixed-combination ophthalmic drops.Case ...
Azarcon, Corrina P., Santiago, Darby E.
doaj +2 more sources
Comparative evaluation of Latanoprostene Bunod, Timolol Maleate, and latanoprost Ophthalmic Solutions to assess their safety and efficacy in lowering intraocular pressure for the management of Open-Angle Glaucoma [PDF]
Clinics, 2020 OBJECTIVES: Timolol maleate has been reported to be a safer intraocular pressure (IOP) lowering treatment than latanoprost. The United States Food and Drug Administration approved latanoprostene bunod, a nitric oxide-donating prodrug of latanoprost, for ...
Yulong Wang, Yue Liao, Xin Nie
doaj +2 more sources
Poly(Sulfobetaine Methacrylate-co-Vinyl Pyrrolidone) Hydrogels as Potential Contact Lenses Delivery Systems for Timolol Maleate [PDF]
Gels, 2023 The study reveals the development of novel hydrogels based on sulfobetaine methacrylate (SB) and vinyl pyrrolidone (VP) copolymers as potential contact lenses delivery systems of timolol maleate (TM). The novel copolymer networks demonstrated composition
Denitsa Nikolova +3 more
doaj +2 more sources
A novel reversed phase high performance liquid chromatography approach for stability-indicating simultaneous analysis of brimonidine tartrate and timolol maleate [PDF]
Frontiers in ChemistryIntroductionThe simultaneous quantification of Brimonidine Tartrate and Timolol Maleate in ophthalmic formulations is essential for ensuring product quality, efficacy, and stability.
Aktham Mestareehi, Aktham Mestareehi
doaj +2 more sources
A stability-indicating RP-HPLC method for the simultaneous quantification of brimonidine tartrate and timolol maleate in bulk drug substances and pharmaceutical dosage forms [PDF]
Scientific ReportsA robust, rapid, and reproducible reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the simultaneous quantification of Brimonidine Tartrate and Timolol Maleate (Combigan) in ophthalmic dosage forms ...
Aktham Mestareehi
doaj +2 more sources
Topical Application of 0.5% Timolol Maleate Hydrogel for the Treatment of Superficial Infantile Hemangioma [PDF]
Frontiers in Oncology, 2017 The therapeutic options for infantile hemangiomas (IHs) have been greatly altered since the introduction of oral propranolol for successful treatments of IHs.
Hai Wei Wu +8 more
doaj +2 more sources
Efficacy Evaluation of 755-nm Long-Pulse Alexandrite Laser Combined with 0.5% Timolol Maleate Eye Drops in the Treatment of Thicker Infantile Hemangioma [PDF]
Clinical, Cosmetic and Investigational Dermatology, 2021 Jianming Wu,* Fangyan Zhou,* Yu Gao Department of Dermatological, Yuying Children’s Hospital, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People’s Republic of China*These authors contributed ...
Wu J, Zhou F, Gao Y
doaj +2 more sources
Transdermal iontophoretic delivery of timolol maleate [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2012 Transdermal iontophoresis would be a promising method for the systemic delivery of water soluble and ionic drugs of relatively high molecular size, including peptides.
Mayur Patni +3 more
doaj +4 more sources