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The efficacy and safety of bimatoprost/timolol maleate, latanoprost/timolol maleate, and travoprost/timolol maleate fixed combinations on 24-h IOP

International Ophthalmology, 2017
To evaluate the effect of bimatoprost/timolol maleate fixed combination (BTFC), latanoprost/timolol maleate fixed combination (LTFC), and travoprost/timolol maleate fixed combination (TTFC) on 24-h intraocular pressure (IOP) in patients with open-angle glaucoma.This prospective, observer-masked, randomized study included 50 patients with primary open ...
Halil Ates   +2 more
exaly   +4 more sources

Timolol Maleate

Definitions, 2020
Timolol Maleate ophthalmic solution is a non-selective beta-adrenergic receptor blocking agent. Its chemical name is (-)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate (1:1) (salt).
D. J. Mazzo, A. Loper
openaire   +2 more sources

Chitosan Nanoparticles for Prolonged Delivery of Timolol Maleate

Drug Development and Industrial Pharmacy, 2007
Timolol maleate-loaded chitosan (CS) nanoparticles were prepared by desolvation method. Experimental variables such as molecular weight of CS and amount of crosslinking agent were varied to study their effect on drug entrapment efficiency, size and release rates of nanoparticles.
Tejraj Aminabhavi
exaly   +3 more sources

Plasma levels and systemic safety of 0.1% unpreserved Timolol maleate gel, 0.5% Timolol aqueous solution and 0.5% Timolol maleate gel

Journal Francais D'Ophtalmologie, 2012
To compare systemic absorption of three formulations of timolol eye drops: 0.1% timolol maleate gel, 0.5% timolol aqueous solution, and 0.5% timolol maleate gel.This was a double cross-over phase I study. Cross-over 1: two weeks of 0.1% timolol gel once daily, followed by a 3-week wash-out period and then two weeks of 0.5% timolol aqueous solution ...
F Chiambaretta, N Bonnin, C Dubray
exaly   +3 more sources

TIMOLOL MALEATE IN TREATMENT OF OPEN ANGLE GLAUCOMA

Acta Ophthalmologica, 1979
The effect of Timolol maleate on the intraocular pressure in open angle glaucoma has been examined in 37 patients, of these simple glaucoma in 26 (48 eyes), capsular glaucoma in 9 (14 eyes) and chronic secondary glaucoma in 2 patients (2 eyes). These cases constituded a group which was relatively difficult to manage.The average pressure reduction ...
J H Seland, H Aasved
exaly   +3 more sources

Treatment of Posttraumatic Reactive Angioendotheliomatosis With Topical Timolol Maleate

JAMA Dermatology, 2021
Riti, Bhatia   +5 more
openaire   +3 more sources

Synthesis and evaluation of modified lens using plasma treatment containing timolol-maleate loaded lauric acid-decorated chitosan-alginate nanoparticles for glaucoma

Journal of Biomaterials Science. Polymer Edition, 2023
Reducing intraocular pressure (IOP) with eye drops is one of the most common ways to control glaucoma. Low bioavailability and high frequency of administration in eye drops are major challenges in ocular pharmacotherapy. Contact lenses have attracted the
Maryam Sadat Hosseini   +6 more
semanticscholar   +1 more source

TIMOLOL MALEATE

Medical Journal of Australia, 1979
A randomized, double-masked trial of various concentrations of timolol maleate ophthalmic solution (0.1%, 0.25%, 0.5%, and 1.0%) vs placebo demonstrated that all concentrations of timolol effectively lowered intraocular pressure (IOP). A 0.5% solution of timolol was as effective in reducing IOP as the 1.0% concentration.
T J, Zimmerman   +3 more
openaire   +4 more sources

RP-HPLC Method Development for Simultaneous Estimation of Brimonidine Tartrate and Timolol Maleate in Ophthalmic Preparation

International Journal of Pharmaceutical Sciences and Nanotechnology, 2023
Introduction: A simple, precise, rapid, and reproducible RP-HPLC method is developed for the simultaneous estimation of brimonidine tartrate and timolol maleate present in ophthalmic dosage forms. Method: Gradient RP-HPLC is carried out at 35℃ on column
A. Patel   +3 more
semanticscholar   +1 more source

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