Results 151 to 160 of about 28,472 (205)

Differences in ocular surface irritation between timolol hemihydrate and timolol maleate

American Journal of Ophthalmology, 2000
We evaluated the anterior segment surface reaction findings between timolol hemihydrate and timolol maleate. The only known difference between these preparations is the maleate salt.After a baseline examination, we randomized 28 healthy subjects (26 completed) to timolol hemihydrate or timolol maleate given in both eyes twice daily, in a double masked ...
W C, Stewart, J A, Stewart, K T, Holmes, J N, Leech   +3 more
openaire   +2 more sources

Analysis of β-blocker timolol maleate drug residues in wastewater and biological fluids using differential pulse – anodic stripping voltammetry

International Journal of Environmental Analytical Chemistry, 2020
Drug residues in water represent one of the most serious environmental problems because of their high toxicity to the biological system. Thus, this study reports a low-cost strategy for fast and precise analysis of β- blocker timolol maleate (TM) using ...
G. I. Mohammed, Hossam Metwally Nassef, A. Bashammakh, Z. Saigl, M. El-Shahawi   +4 more
semanticscholar   +1 more source

A TRIAL OF TIMOPTOL (Timolol Maleate) IN A CLINICAL SITUATION

Australian and New Zealand Journal of Ophthalmology, 1980
The results of treatment with Timoptol in 138 cases are reviewed. There was an average lowering of pressure by 6mm Hg in the whole group with an average follow up of 10 weeks (range 2-26 weeks). Most patients had a satisfactory fall only when Timoptol was combined with other treatment, with a fall of 3mm Hg or more in 60% of patients and with pressure ...
W E, Gilles, R H, West, L, Cebon
openaire   +2 more sources

Effect of Topical Timolol Maleate on Exercise Performance

Archives of Ophthalmology, 1984
The effect of topical timolol maleate on exercise performance was investigated in a randomized double-blind study. Healthy young subjects underwent two graded maximal exercise evaluations on a treadmill. The evaluations were given one week apart. Before each trial, the subjects were given a single drop of either placebo or 0.5% timolol maleate in each ...
W J, Doyle, P A, Weber, R H, Meeks
openaire   +2 more sources

Plasma timolol concentrations of timolol maleate: timolol gel-forming solution (TIMOPTIC-XE®) once daily versus timolol maleate ophthalmic solution twice daily

Documenta Ophthalmologica, 2001
The objective of this study was to compare plasma concentrations of timolol following multiple dosing of the therapeutic regimens of timolol maleate ophthalmic gel-forming solution (Timolol GS; TIMOPTIC-XE) and timolol maleate ophthalmic solution. Timolol maleate ophthalmic gel-forming solution is also referred to as Timolol GS, i.e.
A H, Shedden, J, Laurence, A, Barrish, T V, Olah   +3 more
openaire   +2 more sources

Use of Topical Timolol Maleate as Re-Epithelialization Agent for Treatment of Recalcitrant Wounds of Varying Etiologies.

Journal of Drugs in Dermatology, 2020
Chronic wounds are a source of severe morbidity to patients.1 Wounds are also a notable burden on the healthcare system, with reported prevalence of 4.64% in the U.S. and an annual cost of over 25 billion dollars.2,3 Moreover, wounds are associated with >
Brian A. Cahn, R. Kaur, P. Hirt, C. Tchanque-Fossuo, S. Dahle, R. Kirsner, R. Isseroff, Hadar A. Lev-Tov   +7 more
semanticscholar   +1 more source

Chemometrics-assisted voltammetric determination of timolol maleate and brimonidine tartrate utilizing a carbon paste electrode modified with iron (III) oxide nanoparticles

Microchemical journal (Print), 2019
A carbon paste electrode modified with iron (III) oxide nanoparticles (MCPE) was fabricated for the simultaneous quantitative voltammetric determination of timolol maleate (TM) and brimonidine tartrate (BT) using chemometrics analysis. In this paper, for
A. M. A. A. Alamein, H. Hendawy, N. Elabd   +2 more
semanticscholar   +1 more source

Exploring gelatin nanoparticles as novel nanocarriers for Timolol Maleate: Augmented in‐vivo efficacy and safe histological profile

International journal of pharmaceutics, 2018
The use of gelatin has been gaining recognition in ocular delivery for its safety profile and biocompatible properties. Timolol Maleate (TM) is an anti‐glaucoma drug possessing poor corneal penetration while causing eye irritation making it an ideal ...
M. Shokry, R. Hathout, S. Mansour
semanticscholar   +1 more source

Corneal Anesthesia after Timolol Maleate Therapy

American Journal of Ophthalmology, 1979
Symptomatic superficial punctate keratitis associated with complete corneal anesthesia occurred in three patients after they had been taking timolol maleate for glaucoma. After discontinuation of the timolol maleate and substitution of conventional antiglaucomatous collyria, the keratitis gradually cleared with restoration of normal corneal sensitivity.
openaire   +2 more sources

Spectrochromatographic determination of dorzolamide hydrochloride and timolol maleate in an ophthalmic solution using three-way analysis methods.

Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2019
In this study, the simultaneous spectrochromatographic determination of dorzolamide hydrochloride (DOR) and timolol maleate (TMM) in an ophthalmic formulation was performed by applying multiway resolution methods, parallel factor analysis (PARAFAC) and ...
E. Dinç, E. Büker
semanticscholar   +1 more source