Results 161 to 170 of about 2,736 (198)
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Effect of Indomethacin on the Ocular Hypotensive Action of Timolol Maleate

American Journal of Ophthalmology, 1984
A randomized, double-masked, cross-over study of nine healthy normal subjects was conducted to determine whether indomethacin affected the ocular hypotensive action of timolol maleate. A significant decrease in intraocular pressure occurred with timolol maleate 0.5% eyedrops (used twice a day) alone. Indomethacin (25 mg three times a day, given orally)
M, Lichter   +3 more
openaire   +2 more sources

Timolol maleate and HDL cholesterol after myocardial infarction

European Heart Journal, 1985
The influence of long-term timolol treatment on plasma lipids was analysed in cohorts of the Norwegian timolol multicentre study. The prognostic importance of high-density lipoprotein (HDL) cholesterol concentration after myocardial infarction was also examined. One year timolol treatment was related to a significant reduction in HDL cholesterol levels,
T, Gundersen   +3 more
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Transdermal iontophoretic delivery of timolol maleate in albino rabbits

International Journal of Pharmaceutics, 2000
The use of transdermal iontophoresis is a promising technique for the systemic delivery of water soluble and ionic drugs of relatively large molecular size. The present study investigates the skin pre-treatment with Azone (laurocapram) and iontophoresis on the pharmacodynamic effect of timolol maleate (TM) in vivo in albino rabbits. The pharmacodynamic
N, Kanikkannan, J, Singh, P, Ramarao
openaire   +2 more sources

Safety and Effectiveness of Concomitant Administration of Dipivefrin and Timolol Maleate

American Journal of Ophthalmology, 1981
Dipivefrin, an epinephrine prodromal drug, was used in conjunction with timolol maleate to evaluate the safety and effectiveness of combined therapy. Seventeen patients who had used timolol maleate for at least six months added dipivefrin (Group 1) and seven patients who had used dipivefrin for at least six months added timolol maleate (Group 2 ...
E U, Keates, R A, Stone
openaire   +2 more sources

Timolol Maleat` ın stabilitesi

2020
-31- ÖZET Yeni olarak tedaviye giren timolol maleat'xn miktar ta yini iğin bir s pektro foto metrik metod geliştirilmiştir. Bu me todun hassasiyet hududu 10-300 mcg/ml arasındadır. Bu çalışma da ayrıca timolol malea^ın göz damlası içersinde değişik pH da ve keza değişik sterilizaayon teknikleri uygulanması halin de stabilitesi araştırılmıştır.
openaire   +1 more source

Timolol Maleate and Choroidal Blood Flow

1983
We have measured choroidal blood flow in cats by determining the rate of clearance of indocyanine green dye from the choroidal circulation. Measurements were made by rapidly (0.2 s) injecting indocyanine green dye (2.5 mg/ml), in 0.1 ml increments, into the common carotid artery and photoelectrically monitoring its concentration in the superior ...
J. T. Ernest, T. K. Goldstick
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Timolol Maleate Associated With Phalangeal Swelling

Archives of Ophthalmology, 1991
We report a case in which timolol maleate may have been the cause of phalangeal swelling. Report of a Case. —A 61-year-old white woman has been followed up by our glaucoma service because of advanced, primary open angle glaucoma. Her history included anterior poliomyelitis during childhood, with slight right hemihypertrophy as a sequela. There was no
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Synthesis and Characterization of 3-S-impurities in Timolol Maleate

Current Organic Synthesis
Background: Timolol maleate is clinically used for the treatment of hypertension, angina pectoris, tachycardia, and glaucoma. Objective: The aim of this study was to enhance the safe use of timolol maleate and investigate a synthesis method for 3-S-timolol, a newly identified impurity in timolol API (Active Pharmaceutical Ingredients). Methods: (S)
Dejun Zhou   +4 more
openaire   +2 more sources

[Timolol maleate. Pharmacology and review of the literature].

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1979
The sympathetic system is composed of alpha and beta receptors. Beta blockers block the beta effect competitively. They slow the heart and decrease its contractile strength. They block bronchodilatation and the vasodillation of muscular arteries. Timolol is a non specific beta blocker.
M, Amyot, P, Blondeau
openaire   +1 more source

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