Results 171 to 180 of about 30,734 (250)

TIMOLOL MALEATE

Medical Journal of Australia, 1979
A randomized, double-masked trial of various concentrations of timolol maleate ophthalmic solution (0.1%, 0.25%, 0.5%, and 1.0%) vs placebo demonstrated that all concentrations of timolol effectively lowered intraocular pressure (IOP). A 0.5% solution of timolol was as effective in reducing IOP as the 1.0% concentration.
T J, Zimmerman, M A, Kass, M E, Yablonski, B, Becker   +3 more
openaire   +4 more sources

Topical Application of 0.5% Timolol Maleate Hydrogel for the Treatment of Superficial Infantile Hemangiomas.

Journal of Drugs in Dermatology, 2023
BACKGROUND Oral propranolol is considered the first line therapy in the treatment of infantile hemangiomas (IHs). However, there are considerable side effects due to its ability to penetrate the blood brain barrier.
Farihah Anwar, E. Mahmood, Shawana Sharif, Rohan Shah, Marielle Jamgochian, S. Ouellette, Muhammad Umar, B. Rao   +7 more
semanticscholar   +1 more source

RP-HPLC Method Development for Simultaneous Estimation of Brimonidine Tartrate and Timolol Maleate in Ophthalmic Preparation

International Journal of Pharmaceutical Sciences and Nanotechnology, 2023
Introduction: A simple, precise, rapid, and reproducible RP-HPLC method is developed for the simultaneous estimation of brimonidine tartrate and timolol maleate present in ophthalmic dosage forms. Method: Gradient RP-HPLC is carried out at 35℃ on column
Ajay I. Patel, Anjali K Mandavia, Darshita R Vyas, A. Vyas   +3 more
semanticscholar   +1 more source

Timolol Maleate

Definitions, 2020
Timolol Maleate ophthalmic solution is a non-selective beta-adrenergic receptor blocking agent. Its chemical name is (-)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate (1:1) (salt).
D. J. Mazzo, Alice E. Loper
openaire   +2 more sources

In Situ Gelling Electrospun Ocular Films Sustain the Intraocular Pressure-Lowering Effect of Timolol Maleate: In Vitro, Ex Vivo, and Pharmacodynamic Assessment.

Molecular Pharmaceutics, 2021
Most common intraocular pressure (IOP) reduction regimens for the management of glaucoma include the topical use of eye drops, a dosage form that is associated with short residence time at the site of action, increased dosing frequency, and reduced ...
I. Andreadis, C. Karavasili, Angelos L. N. Thomas, A. Komnenou, Manolis Tzimtzimis, D. Tzetzis, Dimitrios Andreadis, N. Bouropoulos, D. Fatouros   +8 more
semanticscholar   +1 more source

Effect of CYP2D6*4, CYP2D6*10 polymorphisms on the safety of treatment with timolol maleate in patients with glaucoma

Drug Metabolism and Personalized Therapy, 2022
Objectives Timolol maleate is used for the treatment of glaucoma and metabolized by cytochrome CYP2D6 in the liver. The aim of this study was the evaluation of the influence of CYP2D6*4 and CYP2D6*10 gene polymorphisms on the safety of medications ...
L. Moshetova, M. M. Soshina, Ksenia I. Turkina, E. Grishina, Z. Sozaeva, A. Kachanova, K. Akmalova, D. Ivashchenko, M. Zastrozhin, V. Fisenko, D. Sychev   +10 more
semanticscholar   +1 more source

Evaluation of timolol maleate gel for management of hard-to-heal chronic venous leg ulcers. Phase II randomised-controlled study.

Annales de dermatologie et de vénéréologie, 2021
BACKGROUND Venous leg ulcers (VLUs) often take a very long time to heal. Timolol maleate has been reported as displaying efficacy in healing of VLUs. OBJECTIVES To evaluate the efficacy of timolol maleate gel in the management of hard-to-heal VLUs and ...
T. Baltazard, P. Senet, D. Momar, C. Picard, C. Joachim, A. Adas, C. Lok, G. Chaby   +7 more
semanticscholar   +1 more source

Full Factorial Design for Development and Validation of a Stability-Indicating RP-HPLC Method for the Estimation of Timolol Maleate in Surfactant-Based Elastic Nano-Vesicular Systems.

Journal of Chromatographic Science, 2021
A novel isocratic stability-indicating chromatographic method was developed, optimized and validated using Design-Expert® following ICH guidelines for the quantification of Timolol maleate (TM).
Santosh Naik, P. Mullick, Sadhana P. Mutalik, A. Hegde, S. Lewis, K. Bhat, B. S. S. Rao, S. Mutalik   +7 more
semanticscholar   +1 more source

Treatment of Posttraumatic Reactive Angioendotheliomatosis With Topical Timolol Maleate

JAMA Dermatology, 2021
Riti, Bhatia, Neirita, Hazarika, Divya, Chandrasekaran, Vishal, Gupta, Prashant, Durgapal, Sanjeev, Kishore   +5 more
openaire   +3 more sources

The efficacy and safety of bimatoprost/timolol maleate, latanoprost/timolol maleate, and travoprost/timolol maleate fixed combinations on 24-h IOP

International Ophthalmology, 2017
To evaluate the effect of bimatoprost/timolol maleate fixed combination (BTFC), latanoprost/timolol maleate fixed combination (LTFC), and travoprost/timolol maleate fixed combination (TTFC) on 24-h intraocular pressure (IOP) in patients with open-angle glaucoma.This prospective, observer-masked, randomized study included 50 patients with primary open ...
Yilmaz, Suzan Guven, Degirmenci, Cumali, Karakoyun, Yunus Emre, Yusifov, Emil, Ates, Halil   +4 more
openaire   +3 more sources