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Synthesis and Characterization of 3-S-impurities in Timolol Maleate
Current Organic SynthesisBackground: Timolol maleate is clinically used for the treatment of hypertension, angina pectoris, tachycardia, and glaucoma. Objective: The aim of this study was to enhance the safe use of timolol maleate and investigate a synthesis method for 3-S-timolol, a newly identified impurity in timolol API (Active Pharmaceutical Ingredients). Methods: (S)
Dejun Zhou +4 more
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[Timolol maleate. Pharmacology and review of the literature].
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1979The sympathetic system is composed of alpha and beta receptors. Beta blockers block the beta effect competitively. They slow the heart and decrease its contractile strength. They block bronchodilatation and the vasodillation of muscular arteries. Timolol is a non specific beta blocker.
M, Amyot, P, Blondeau
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A Comparison of Timolol Maleate and Levobunolol
Ophthalmology, 1994Marcus A. Meyer, Michael L. Savitt
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Topical timolol maleate for treatment of tufted angioma
The Journal of Dermatology, 2019Bin Zhang +5 more
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