Results 141 to 150 of about 2,736 (198)

The efficacy and safety of bimatoprost/timolol maleate, latanoprost/timolol maleate, and travoprost/timolol maleate fixed combinations on 24-h IOP

open access: yesInternational Ophthalmology, 2017
To evaluate the effect of bimatoprost/timolol maleate fixed combination (BTFC), latanoprost/timolol maleate fixed combination (LTFC), and travoprost/timolol maleate fixed combination (TTFC) on 24-h intraocular pressure (IOP) in patients with open-angle glaucoma.This prospective, observer-masked, randomized study included 50 patients with primary open ...
Cumali Degirmenci   +2 more
exaly   +5 more sources
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Chitosan Nanoparticles for Prolonged Delivery of Timolol Maleate

Drug Development and Industrial Pharmacy, 2007
Timolol maleate-loaded chitosan (CS) nanoparticles were prepared by desolvation method. Experimental variables such as molecular weight of CS and amount of crosslinking agent were varied to study their effect on drug entrapment efficiency, size and release rates of nanoparticles.
Sunil A Agnihotri, Tejraj M Aminabhavi
exaly   +3 more sources

Plasma levels and systemic safety of 0.1% unpreserved Timolol maleate gel, 0.5% Timolol aqueous solution and 0.5% Timolol maleate gel

Journal Francais D'Ophtalmologie, 2012
To compare systemic absorption of three formulations of timolol eye drops: 0.1% timolol maleate gel, 0.5% timolol aqueous solution, and 0.5% timolol maleate gel.This was a double cross-over phase I study. Cross-over 1: two weeks of 0.1% timolol gel once daily, followed by a 3-week wash-out period and then two weeks of 0.5% timolol aqueous solution ...
N Bonnin, C Dubray, F Chiambaretta
exaly   +3 more sources

TIMOLOL MALEATE IN TREATMENT OF OPEN ANGLE GLAUCOMA

Acta Ophthalmologica, 1979
The effect of Timolol maleate on the intraocular pressure in open angle glaucoma has been examined in 37 patients, of these simple glaucoma in 26 (48 eyes), capsular glaucoma in 9 (14 eyes) and chronic secondary glaucoma in 2 patients (2 eyes). These cases constituded a group which was relatively difficult to manage.The average pressure reduction ...
Henry Aasved, Johan H Seland
exaly   +3 more sources

TIMOLOL MALEATE

Medical Journal of Australia, 1979
A randomized, double-masked trial of various concentrations of timolol maleate ophthalmic solution (0.1%, 0.25%, 0.5%, and 1.0%) vs placebo demonstrated that all concentrations of timolol effectively lowered intraocular pressure (IOP). A 0.5% solution of timolol was as effective in reducing IOP as the 1.0% concentration.
T J, Zimmerman   +3 more
openaire   +4 more sources

Simultaneous determination of dorzolamide HCL and timolol maleate in eye drops by two different spectroscopic methods

open access: yesJournal of Pharmaceutical and Biomedical Analysis, 2002
Two-component mixtures of dorzolamide hydrochloride and timolol maleate were assayed by first derivative and ratio derivative spactrophotometric methods.
Nevin Erk
exaly   +2 more sources

Uncertainty assessment from robustness testing applied on an LC assay for R-timolol and other related substances in S-timolol maleate

open access: yesAnalytica Chimica Acta, 2005
peer reviewedThe robustness testing of a normal-phase liquid chromatographic (LC) method for the determination of R-timolol and other related substances in S-timolol maleate was performed applying a two-level Plackett-Burman design.
R D Marini   +2 more
exaly   +2 more sources

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