Approaches in topical ocular drug delivery and developments in the use of contact lenses as drug-delivery devices [PDF]
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Drug-delivery approaches have diversified over the last two decades with the emergence of nanotechnologies,
Acheampong A +17 more
core +2 more sources
Currently commercial fixed-concomitant three agents have multiple problems such as multiple dosing administration, poor efficacy and side effects. Once-daily fixed-combination timolol-netarsudil-latanoprost ophthalmic solution (FC-TNL) has the ability to
Tao Wang +8 more
doaj +1 more source
Effects of the timolol-dorzolamide fixed combination and latanoprost on circadian diastolic ocular perfusion pressure in glaucoma. [PDF]
PURPOSE. To evaluate the effect of the timolol-dorzolamide fixed combination (TDFC) and latanoprost 0.005% on 24-hour intraocular pressure (IOP), systolic (SBP) and diastolic (DBP) blood pressure, and diastolic ocular perfusion pressure (DOPP) in ...
Floriani I. +4 more
core +1 more source
The Efficacy and Safety of Atenolol for Treatment of Infantile Hemangioma
ABSTRACT Background Infantile hemangiomas are the most common benign vascular tumours in children. Since the discovery of propranolol for infantile hemangiomas, its increasing side effect profile has prompted research into its beta‐1‐selective counterpart, atenolol.
Michelle Shi +3 more
wiley +1 more source
Carbon Paste Electrode with Au/Pd/MWCNT Nanocomposite for Nanomolar Determination of Timolol
Fabrication of Au/Pd/MWCNT nanocomposite was performed by using chemical method. The nanocomposite was characterized by scanning electron microscopy (SEM), energy-dispersive X-Ray spectroscopy (EDS) and electrochemical methods.
Khadijeh Nekoueian +2 more
doaj +1 more source
Topical timolol for treatment of persistent granulation tissue in the setting of severe hidradenitis suppurativa [PDF]
Hidradenitis suppurativa (HS) is a potentially debilitating dermatological disease that negatively impacts patients' quality of life. Severe cases can be further complicated by persistent granulation tissue at the ostia of sinus tracts, which may prove ...
Chen, Xizhao, Guffey, Darren J
core
Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov +8 more
wiley +1 more source
Topical Timolol Maleate Treatment of Infantile Hemangiomas
BACKGROUND: There has been a dramatic increase in the off-label use of ophthalmic timolol maleate, a β-blocker used for infantile hemangioma (IH) treatment as a topical counterpart to oral propranolol. Its safety and efficacy in a pediatric population with IH have not been evaluated in a large cohort.
Puttgen, K +20 more
openaire +3 more sources
Multicomponent pharmaceutical products, particularly fixed‐dose combinations (FDCs), have become increasingly important in modern therapeutics to improve patient adherence and therapeutic outcomes. Although chromatographic techniques are widely employed for their analysis, ultraviolet‐visible (UV‐Vis) spectrophotometry remains an attractive alternative
Imad Osman Abu Reid +1 more
wiley +1 more source
Identification of β2-adrenoceptors on guinea pig alveolar macrophages using (-)-3-[125I]iodocyanopindolol [PDF]
The β-adrenoceptor antagonist (-)-3-[125I]iodocyanopindolol ([125I]ICYP) binds with high affinity and in a saturable way to membranes of guinea pig alveolar macrophages.
Amsterdam, J.G.C. (Jan) van +4 more
core +2 more sources

