Results 11 to 20 of about 7,936 (162)

Protective effects of tiotropium alone or combined with budesonide against cadmium inhalation induced acute neutrophilic pulmonary inflammation in rats. [PDF]

open access: yesPLoS ONE, 2018
As a potent bronchodilator, the anti-inflammatory effects of tiotropium and its interaction with budesonide against cadmium-induced acute pulmonary inflammation were investigated.
Shiwei Zhao   +6 more
doaj   +1 more source

Effects of tiotropium on the risk of coronary heart disease in patients with COPD: a nationwide cohort study

open access: yesScientific Reports, 2022
Inhaled long-acting muscarinic antagonist (LAMA) is recommended for the treatment of chronic obstructive pulmonary disease (COPD). However, there is still concern that LAMA may cause cardiovascular adverse events in COPD patients.
Jiyoung Shin, Jin Hwa Lee
doaj   +1 more source

Real-world effectiveness of early intervention with fixed-dose tiotropium/olodaterol vs tiotropium in Japanese patients with COPD: a high-dimensional propensity score–matched cohort analysis

open access: yesRespiratory Research, 2021
Background Escalation to triple therapy (long-acting muscarinic antagonist/β2-agonist, inhaled corticosteroid [ICS]) in chronic obstructive pulmonary disorder (COPD) is recommended for patients on LAMA/LABA combinations with frequent exacerbations and ...
Shigeo Muro   +6 more
doaj   +1 more source

Update on Long-Acting Anticholinergics in Children and Adolescents With Difficult and Severe Asthma

open access: yesFrontiers in Pediatrics, 2022
Tiotropium bromide is the only long-acting muscarinic antagonist (LAMA) approved for treatment of patients aged ≥6 years old who have symptoms of uncontrolled asthma.
Francesca Santamaria   +4 more
doaj   +1 more source

Effect of Tiotropium Bromide on Airway Inflammation and Programmed Cell Death 5 in a Mouse Model of Ovalbumin-Induced Allergic Asthma

open access: yesCanadian Respiratory Journal, 2019
Rationale. We previously demonstrated increased expression of programmed cell death 5 (PDCD5) in asthmatic patients and ovalbumin-induced allergic asthma.
Juan Wang   +3 more
doaj   +1 more source

Skin reaction to inhaled tiotropium bromide: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Systemic reactions to inhaled drugs are rare. To the best of our knowledge, we report the first case of generalized itching related to the use of tiotropium bromide, a long acting inhaled anti-cholinergic agent commonly used to treat chronic
Megali Raffaella   +3 more
doaj   +1 more source

Tiotropium in the add-on treatment of asthma in adults: clinical trial evidence and experience

open access: yesTherapeutic Advances in Respiratory Disease, 2016
Asthma is a chronic inflammatory airway disease, and its treatment is frequently challenging despite detailed national and international guidelines. While basic anti-inflammatory therapy usually consists of inhaled corticosteroids in doses adapted to the
Christian Vogelberg
doaj   +1 more source

Comparison of clinical efficacy and safety between indacaterol and tiotropium in COPD: meta-analysis of randomized controlled trials. [PDF]

open access: yesPLoS ONE, 2015
Two once-daily inhaled bronchodilators, indacaterol and tiotropium, are widely used as first-line therapy in stable COPD patients. This study was performed to compare the clinical efficacy and safety between indacaterol and tiotropium in patients with ...
Jung Soo Kim   +10 more
doaj   +1 more source

Tiotropium: a new therapeutic option in asthma

open access: yesMonaldi Archives for Chest Disease, 2013
Tiotropium: a new therapeutic option in asthma. F. Novelli, F. Costa, M. Latorre, L. Malagrinò, A. Celi, B. Vagaggini, P. Paggiaro. Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic ...
F. Novelli   +6 more
doaj   +1 more source

Low Dose Theophylline and Tiotropium Rotacap as Add on Therapy in COPD Patients-Clinical Trial

open access: yesJournal of Bahria University Medical and Dental College, 2021
Objectives: To compare the role of low dose Theophylline and Tiotropium rotacap in improving the lung functions and day to day life of patients suffering from COPD.
Muzna Hameed Dar   +4 more
doaj   +1 more source

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