Results 61 to 70 of about 5,625 (178)

Lung function and long-term safety of tiotropium/olodaterol in East Asian patients with chronic obstructive pulmonary disease

International Journal of COPD, 2017
Chunxue Bai,1 Masakazu Ichinose,2 Sang Haak Lee,3 Kwan Ho Lee,4 Olaf Jöns,5 Ulrich Bothner,6 Yihua Zhao,7 Roland Buhl8 1Department of Pulmonary Medicine, Shanghai Respiratory Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China;
Bai C, Ichinose M, Lee SH, Lee KH, Jöns O, Bothner U, Zhao Y, Buhl R   +7 more
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Pharmacokinetics and tolerability (Study 1) with particular reference to ocular safety (Study 2) of tiotropium Respimat® Soft Mist™ Inhaler: findings from two dose-ranging studies in healthy men

International Journal of COPD, 2008
Ulrich Feifel1, Gudrun Wallenstein1, Karl-Ludwig Rominger1, Dirk Trommeshauser2, Juliane Platz21Boehringer Ingelheim Pharma GmbH & Co. KG, Binger Straße 173, 55216 Ingelheim, Germany; 2Boehringer Ingelheim Pharma GmbH & Co.
Ulrich Feifel, Gudrun Wallenstein, Karl-Ludwig Rominger, Dirk Trommeshauser, Juliane Platz   +4 more
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Improvement in 24-hour bronchodilation and symptom control with aclidinium bromide versus tiotropium and placebo in symptomatic patients with COPD: post hoc analysis of a Phase IIIb study

International Journal of COPD, 2017
Jutta Beier,1 Robert Mroz,2,3 Anne-Marie Kirsten,4 Ferran Chuecos,5 Esther Garcia Gil5 1insaf Respiratory Research Institute, Wiesbaden, Germany; 2Centrum Medycyny Oddechowej, 3Medical University of Białystok, Białystok, Poland; 4Pulmonary Research ...
Beier J, Mroz R, Kirsten AM, Chuecos F, Garcia Gil E   +4 more
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Tiotropium and exercise training in COPD patients: Effects on dyspnea and exercise tolerance

International Journal of COPD, 2008
Nicolino Ambrosino1, Katia Foglio2, Gianni Balzano2, Pier Luigi Paggiaro1, Patrizia Lessi3, Steven Kesten3 On behalf of the Tiotropium Multicentric Italian Study Group1Cardio-Thoracic Department, University Hospital, Pisa, Italy; 2S Maugeri Foundation ...
Nicolino Ambrosino, Katia Foglio, Gianni Balzano, Pier Luigi Paggiaro, Patrizia Lessi, Steven Kesten   +5 more
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Expression of Muscarinic Receptors and the Effect of Tiotropium Bromide in Aged Mouse Model of Chronic Asthma

Tuberculosis and Respiratory Diseases, 2019
Background Efficacy and safety of tiotropium bromide, a muscarinic receptor antagonist, in treatment of asthma have been reported. However, its effect on airway remodeling in chronic asthma of the elderly has not been clearly verified.
Ji Young Kang, M.D., Ph.D., In Kyoung Kim, Ph.D., Jung Hur, Ph.D., Seok Chan Kim, M.D., Ph.D., Sook Young Lee, M.D., Ph.D., Soon Seog Kwon, M.D., Ph.D., Young Kyoon Kim, M.D., Ph.D.   +6 more
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The role of tiotropium in the management of asthma [PDF]

Asia Pacific Allergy, 2012
Asthma is a chronic respiratory disease characterized by reversible airway obstruction that is secondary to an allergic inflammation and excessive smooth muscle contraction. Cholinergic signals were known to contribute significantly to the pathophysiology of asthma.
openaire   +2 more sources

Analisis Efektivitas Biaya Terapi Tiotropium Bromide Dibandingkan dengan Salmeterol/Fluticasone Propionate pada Pasien Penyakit Paru Obstruktif Kronik (PPOK) di RSUD Tabanan

JPSCR: Journal of Pharmaceutical Science and Clinical Research
Penyakit paru obstruktif kronik (PPOK) merupakan penyakit progresif yang membutuhkan terapi jangka panjang dengan bronkodilator. Dua terapi yang banyak digunakan adalah golongan long-acting muscarinic antagonists (LAMA) yaitu Tiotropium Bromide (Spiriva®)
Sagung Chandra Yowani, Yayanasri Yayanasri, Rasmaya Niruri, Rini Noviyani   +3 more
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Tiotropium inhibits methacholine-induced extracellular matrix production via β-catenin signaling in human airway smooth muscle cells

International Journal of COPD, 2018
Yating Huo, Lili Guan, Jiawen Xu, Luqian Zhou, Rongchang Chen State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China Background: Airway ...
Huo Y, Guan L, Xu J, Zhou L, Chen R
doaj  

Tiotropium HandiHaler® in the treatment of COPD: A safety review

International Journal of COPD, 2009
Steven Kesten1, Bart Celli2, Marc Decramer3, Inge Leimer4, Donald Tashkin51Boehringer Ingelheim Pharmaceuticals; Ridgefield, CT, USA; 2Caritas St. Elizabeth’s Medical Center, Boston, MA, USA; 3University of Leuven, Leuven, Belgium; 4Boehringer ...
Steven Kesten, Bart Celli, Marc Decramer, et al   +3 more
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Long-term safety of tiotropium/olodaterol Respimat® in patients with moderate-to-very severe COPD and renal impairment in the TONADO® studies

International Journal of COPD, 2018
Craig LaForce,1 Eric Derom,2 Ulrich Bothner,3 Isabel M Kloer,3 Matthias Trampisch,4 Roland Buhl5 1NC Clinical Research, Raleigh, NC, USA; 2Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; 3Pharmacovigilance, Boehringer ...
LaForce C, Derom E, Bothner U, Kloer IM, Trampisch M, Buhl R   +5 more
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