Results 51 to 60 of about 8,104 (211)

Non‐Linear Dysanaptic Lung Growth in Patients With Post‐Infectious Bronchiolitis Obliterans

Pediatric Pulmonology, Volume 61, Issue 7, July 2026.
ABSTRACT Introduction Few studies have assessed longitudinal pulmonary function outcomes in post‐infectious bronchiolitis obliterans (PIBO). This study analyzes pulmonary function changes from patients with PIBO at a single center with respect to time and inciting respiratory pathogen.
James M. Clegg, Ferdinand Cacho, Matthew D. McGraw, Michael G. O'Connor   +3 more
wiley   +1 more source

Effect of 12 weeks of once-daily tiotropium/olodaterol on exercise endurance during constant work-rate cycling and endurance shuttle walking in chronic obstructive pulmonary disease

Therapeutic Advances in Respiratory Disease, 2018
Background: The TORRACTO ® study evaluated the effects of tiotropium/olodaterol versus placebo on endurance time during constant work-rate cycling and constant speed shuttle walking in patients with chronic obstructive pulmonary disease (COPD) after 12 ...
François Maltais, Denis O’Donnell, Juan Bautista Gáldiz Iturri, Anne-Marie Kirsten, Dave Singh, Alan Hamilton, Kay Tetzlaff, Yihua Zhao, Richard Casaburi   +8 more
doaj   +1 more source

Tiotropium/Olodaterol treatment reduces cigarette smoke extract-induced cell death in BEAS-2B bronchial epithelial cells

BMC Pharmacology and Toxicology, 2020
Background Cigarette smoking is a critical risk factor for the destruction of lung parenchyma or the development of emphysema, which is characteristic of COPD.
Cheng-hsiung Chen, Yi-Rong Li, Sheng-Hao Lin, Hsiu-Hui Chang, Woei-Horng Chai, Po-Chiang Chan, Ching-Hsiung Lin   +6 more
doaj   +1 more source

Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis

International Forum of Allergy &Rhinology, Volume 16, Issue 6, Page 607-614, June 2026.
ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman, Spencer Short, Emma Tam, Benjamin F. Bitner, Abdulghafoor Alani, Marc Rosen, Mindy Rabinowitz, Damaris Pena Evertz, Elina Toskala, Gurston G. Nyquist   +9 more
wiley   +1 more source

Tiotropium bromide as adjunct therapy in children with asthma: a clinical experience

Allergy, Asthma & Clinical Immunology, 2021
Background The Global Initiative for Asthma has only recently added tiotropium bromide as adjunct controller therapy in severe asthma (Step 4 or 5) in adults (2015) and children (2019). Although not yet approved for pediatric use by Health Canada, it has
Zainab Ridha, Marc-Antoine Bédard, Anna Smyrnova, Olivier Drouin, Aniela Pruteanu, Sandrine Essouri, Francine M. Ducharme   +6 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Effects of baseline symptom burden on treatment response in COPD

International Journal of COPD, 2019
Fernando J Martinez,1 Roger A Abrahams,2,3 Gary T Ferguson,4 Leif Bjermer,5 Lars Grönke,6 Florian Voß,7 Dave Singh8 1Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical College, New York, NY, USA; 2Morgantown Pulmonary ...
Martinez FJ, Abrahams RA, Ferguson GT, Bjermer L, Grönke L, Voß F, Singh D   +6 more
doaj  

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda, Renu Khasa, Srinivasan Chinnapaiyan, Saurabh Aggarwal, Irfan Rahman, Hoshang Unwalla   +5 more
wiley   +1 more source

Horizontal Heart Orientation as a Mechanistic Contributor to Platypnea–Orthodeoxia Syndrome in Patent Foramen Ovale

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Altered cardiac orientation in the presence of a patent foramen ovale (PFO) can contribute to platypnea–orthodeoxia syndrome (POS) and unexplained hypoxemia. In such cases, consideration of PFO closure may lead to significant clinical improvement.
Bijeta Keisham, Sanchit Duhan, Uday B. Kanakadandi, Osama Alsara, Naveed A. Adoni, Sanjay S. Mehta, Andrea Brasch, Haseeb Basha, Vishesh Paul   +8 more
wiley   +1 more source

Development of an enhanced health-economic model and cost-effectiveness analysis of tiotropium + olodaterol Respimat fixed-dose combination for chronic obstructive pulmonary disease patients in Italy

Therapeutic Advances in Respiratory Disease, 2016
Background: The objective of this study was to compare the cost-effectiveness of the fixed-dose combination (FDC) of tiotropium + olodaterol Respimat ® FDC with tiotropium alone for patients with chronic obstructive pulmonary disease (COPD) in the ...
Carl Selya-Hammer, Nuria Gonzalez-Rojas Guix, Michael Baldwin, Andrew Ternouth, Marc Miravitlles, Maureen Rutten-van Mölken, Lucas M.A. Goosens, Nasuh Buyukkaramikli, Valentina Acciai   +8 more
doaj   +1 more source