Results 91 to 100 of about 5,292 (260)
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton+4 more
wiley +1 more source
Long-acting beta2-agonists for chronic obstructive pulmonary disease. [PDF]
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a respiratory disease that causes progressive symptoms of breathlessness, cough and mucus build-up.
Aalbers+198 more
core +1 more source
The role of different substituents in position 2 of 6,6‐diphenyl‐1,4‐dioxane muscarinic receptor ligands in the affinity for the five muscarinic acetylcholine receptor (mAChR) subtypes was studied. The tertiary amine 9 and its eutomer (S)‐(–)‐9 showed picomolar affinity and biphasic curves for all mAChRs.
Gianfabio Giorgioni+10 more
wiley +1 more source
Extrafine beclomethasone/formoterol in severe COPD patients with history of exacerbations [PDF]
The FORWARD study is a randomised, double-blind trial that compares the efficacy and safety of 48 weeks treatment with extrafine beclomethasone dipropionate/formoterol fumarate (BDP/FOR), 100/6 μg pMDI, 2 inhalations BID, vs. FOR 12 μg pMDI, 1 inhalation
Agusti, A+10 more
core +1 more source
Regulatory factors of ILC2 are therapeutic targets for lung inflammation
ILC2s is a significant population of innate immune cells, which are activated by epithelial‐derived alarmins IL‐25, IL‐33 and TSLP to secrete type 2 cytokines, playing important role in the regulation of lung inflammation. This article reviews the various factors regulating ILC2s in lung inflammation, especially in allergic diseases.
Lele Cui, Yajie Wang
wiley +1 more source
Van-e cardiovascularis mellékhatásuk az inhalációs antikolinerg szereknek? [PDF]
Absztrakt Az összefoglaló célja az inhalációs antikolinerg szerek cardiovascularis veszélyének tárgyalása krónikus obstruktív tüdőbetegségben.
Nagy, László Béla
core +1 more source
COPD: Optimizing Treatment [PDF]
A guideline update and an expanded armamentarium have many physicians wondering how best to treat patients with COPD. Chronic obstructive pulmonary disease (COPD) carries a high disease burden. In 2012, it was the 4th leading cause of death worldwide.1,2
Ahmed-Sarwar, Nabila+2 more
core +1 more source
The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler® (ENERGITO® study) [PDF]
Background: Tiotropium + olodaterol has demonstrated improvements beyond lung function benefits in a large Phase III clinical program as a once-daily maintenance treatment for COPD and may be a potential option for the initiation of maintenance treatment
Beeh, Kai-Michael+6 more
core +2 more sources
Background and Objectives: Severe asthma seen in substantial proportion of patients has been a poorly controlled disease, with recurring symptoms and exacerbations despite the use of inhaled glucocorticoids (ICS), long-acting beta-agonists (LABAs-2 ...
V G Santhosh+2 more
doaj +1 more source
Two cases of respiratory infection due to Pasteurella multocida: Acute and chronic form
We present two cases of respiratory infection caused by P. multocida, effectively managed with penicillin antibiotics, illustrating both chronic and acute courses. These cases indicate the importance of considering P. multocida in respiratory infections, given the patients' history of pet ownership and the nonspecific imaging findings and symptoms ...
Hironoshin Onizuka+4 more
wiley +1 more source