Results 91 to 100 of about 5,292 (260)

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton   +4 more
wiley   +1 more source

Long-acting beta2-agonists for chronic obstructive pulmonary disease. [PDF]

open access: yes, 2013
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a respiratory disease that causes progressive symptoms of breathlessness, cough and mucus build-up.
Aalbers   +198 more
core   +1 more source

New potent muscarinic receptor ligands bearing the 1,4‐dioxane nucleus: Investigation on the nature of the substituent in position 2

open access: yesArchiv der Pharmazie, Volume 357, Issue 10, October 2024.
The role of different substituents in position 2 of 6,6‐diphenyl‐1,4‐dioxane muscarinic receptor ligands in the affinity for the five muscarinic acetylcholine receptor (mAChR) subtypes was studied. The tertiary amine 9 and its eutomer (S)‐(–)‐9 showed picomolar affinity and biphasic curves for all mAChRs.
Gianfabio Giorgioni   +10 more
wiley   +1 more source

Extrafine beclomethasone/formoterol in severe COPD patients with history of exacerbations [PDF]

open access: yes, 2014
The FORWARD study is a randomised, double-blind trial that compares the efficacy and safety of 48 weeks treatment with extrafine beclomethasone dipropionate/formoterol fumarate (BDP/FOR), 100/6 μg pMDI, 2 inhalations BID, vs. FOR 12 μg pMDI, 1 inhalation
Agusti, A   +10 more
core   +1 more source

Regulatory factors of ILC2 are therapeutic targets for lung inflammation

open access: yesiLABMED, Volume 2, Issue 3, Page 205-220, September 2024.
ILC2s is a significant population of innate immune cells, which are activated by epithelial‐derived alarmins IL‐25, IL‐33 and TSLP to secrete type 2 cytokines, playing important role in the regulation of lung inflammation. This article reviews the various factors regulating ILC2s in lung inflammation, especially in allergic diseases.
Lele Cui, Yajie Wang
wiley   +1 more source

Van-e cardiovascularis mellékhatásuk az inhalációs antikolinerg szereknek? [PDF]

open access: yes, 2015
Absztrakt Az összefoglaló célja az inhalációs antikolinerg szerek cardiovascularis veszélyének tárgyalása krónikus obstruktív tüdőbetegségben.
Nagy, László Béla
core   +1 more source

COPD: Optimizing Treatment [PDF]

open access: yes, 2015
A guideline update and an expanded armamentarium have many physicians wondering how best to treat patients with COPD. Chronic obstructive pulmonary disease (COPD) carries a high disease burden. In 2012, it was the 4th leading cause of death worldwide.1,2
Ahmed-Sarwar, Nabila   +2 more
core   +1 more source

The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler® (ENERGITO® study) [PDF]

open access: yes, 2016
Background: Tiotropium + olodaterol has demonstrated improvements beyond lung function benefits in a large Phase III clinical program as a once-daily maintenance treatment for COPD and may be a potential option for the initiation of maintenance treatment
Beeh, Kai-Michael   +6 more
core   +2 more sources

Clinical effectiveness of anticholinergic tiotropium bromide as an add-on therapy in patients with severe bronchial asthma: A randomized controlled trial

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU, 2017
Background and Objectives: Severe asthma seen in substantial proportion of patients has been a poorly controlled disease, with recurring symptoms and exacerbations despite the use of inhaled glucocorticoids (ICS), long-acting beta-agonists (LABAs-2 ...
V G Santhosh   +2 more
doaj   +1 more source

Two cases of respiratory infection due to Pasteurella multocida: Acute and chronic form

open access: yesRespirology Case Reports, Volume 12, Issue 5, May 2024.
We present two cases of respiratory infection caused by P. multocida, effectively managed with penicillin antibiotics, illustrating both chronic and acute courses. These cases indicate the importance of considering P. multocida in respiratory infections, given the patients' history of pet ownership and the nonspecific imaging findings and symptoms ...
Hironoshin Onizuka   +4 more
wiley   +1 more source

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