Results 101 to 110 of about 3,023 (195)

Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study

, 2009
Background: The efficacy of inhaled salmeterol plus fluticasone propionate (SFC) in patients with severe or very severe COPD is well documented. However, there are only limited data about the influence of GOLD severity staging on the effectiveness of ...
Jones, Paul W, Yates, Julie C, Jones, PW, Yates Julie C, Vestbo Jörgen, Jenkins, Christine R, Willits, LR, Celli Bartolome, Willits Lisa R, Anderson, Julie A., Calverley, PMA, Calverley, PM, Willits, Lisa R., Julie A Anderson, Jörgen Vestbo, Anderson Julie A, Yates, JC, Calverley Peter MA, Anderson, JA, Vestbo, Jörgen, Jones Paul W, Ferguson Gary T, Christine R Jenkins, Jenkins, CR, Ferguson, GT, Gary T Ferguson, Anderson, Julie A, Vestbo, Jorgen; id_orcid, Celli, Bartolome, Bartolome Celli, Peter MA Calverley, Lisa R Willits, Ferguson, Gary T., Calverley, Peter M A, Ferguson, Gary T, Vestbo, J, Jenkins Christine R, Jenkins, CR ; https://orcid.org/, Celli, B, Paul W Jones, Jones, Paul W., Jenkins, Christine R., Julie C Yates, Willits, Lisa R, Yates, Julie C.   +44 more
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Long-acting muscarinic antagonists for the prevention of exacerbations of chronic obstructive pulmonary disease

Therapeutic Advances in Respiratory Disease, 2015
Exacerbations of chronic obstructive pulmonary disease (COPD) have important consequences for lung function, health status and mortality. Furthermore, they are associated with high economic costs, predominantly related to hospitalization.
Paul W. Jones
doaj   +1 more source

A comparative study of safety and efficacy of tiotropium bromide with salbutamol in moderate persistent bronchial asthma in a tertiary care hospital

, 2017
Background: The objective of this study was to compare the safety and efficacy of tiotropium bromide with salbutamol in moderate persistent cases of bronchial asthma at tertiary care hospital.
N, Rajyalakshmi, B, Ramanath, S, Vijaya
core  

Cost-utility of tiotropium in patients with severe asthma

Cost Effectiveness and Resource Allocation
Summary Add-on therapy with tiotropium was cost-effective when added to usual care in patients who remain uncontrolled despite treatment with medium or high-dose ICS/LABA in a middle-income country.
Jefferson Antonio Buendía, Diana Guerrero Patiño   +1 more
doaj   +1 more source

Comparative efficacy of aclidinium versus glycopyrronium and tiotropium, as maintenance treatment of moderate to severe COPD patients: a systematic review and network meta-analysis

International Journal of COPD, 2013
Andreas Karabis,1 Leandro Lindner,2 Michelle Mocarski,3 Eline Huisman,1 Andrew Greening4 1MAPI Consultancy, AX Houten, The Netherlands; 2Almirall SA, Barcelona, Spain; 3Health Economics and Outcomes Research, Forest Research Institute, Jersey City, NJ ...
Karabis A, Lindner L, Mocarski M, Huisman E, Greening A   +4 more
doaj  

Clinical potential of aclidinium bromide in chronic obstructive pulmonary disease

, 2014
Jun Zhong, Michael Roth Pneumology and Pulmonary Cell Research, Department of Biomedicine and Internal Medicine, University Hospital Basel, Basel, Switzerland Abstract: Chronic obstructive pulmonary disease (COPD) is increasing worldwide and is ...
Roth M, Zhong J
core  

Tiotropium Bromide as an Adjunct Therapy to Inhaled Corticosteroids in the Treatment of Adults With Chronic Asthma

, 2011
Background: Asthma is a chronic respiratory disease effecting 24.6 million children and adults in the United States. Current treatment guidelines recommend the use of inhaled corticosteroids and both short and long acting beta agonists.
Dennis, Kevin M
core  

Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling

, 2005
Rationale: Recent findings have demonstrated that muscarinic M-3 receptor stimulation enhances airway smooth muscle proliferation to peptide growth factors in vitro.
Zaagsma, Hans, Meurs, Herman, Gosens, Reinout, Bos, I.S.   +3 more
core   +1 more source

The pharmacokinetics, pharmacodynamics and tolerability of PUR0200, a novel tiotropium formulation, in chronic obstructive pulmonary disease:PUR0200, a tiotropium formulation, in COPD

, 2018
AimsPUR0200 is a tiotropium bromide formulation engineered with the iSPERSE dry powder delivery technology. PUR0200 is being developed as a bioequivalent alternative to tiotropium bromide, delivered using Spiriva® HandiHaler® (HH).
Schmalbach, Tess, Kane, Katie, Hava, David L., Ravi, Arjun, Singh, Dave   +4 more
core   +1 more source

Role of Tiotropium as Step Up Therapy for Asthma

Journal of Rawalpindi Medical College, 2013
Background: To determine the role of Tiotropium as step up therapy for patients with uncontrolled asthma. Methods: In this case control study 130 patients, with diagnosis of bronchial asthma for at least 01 year and presently on step 4 treatment and ...
Muhammad Usman Ullah
doaj