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Tiotropium bromide for cystic fibrosis
Expert Opinion on Orphan Drugs, 2015Introduction: Airway obstruction is a common feature in cystic fibrosis (CF) patients and bronchodilators, either short or long acting, are widely used in CF care.Areas covered: Tiotropium bromide is a long-acting anticholinergic muscarinic receptor antagonist, leading to bronchodilation and to a lesser extent reduction of airway secretions.
Saadoun Bin-Hasan, Felix Ratjen
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Tiotropium bromide for chronic obstructive pulmonary disease
Expert Review of Respiratory Medicine, 2009Tiotropium bromide is a long-acting, once-daily inhaled anticholinergic approved for the treatment of chronic obstructive pulmonary disease (COPD). Functional and kinetic selectivity for muscarinic (M) receptors, M(1) and M(3), in the lung permit sustained bronchodilation in moderate and severe COPD.
A James, Mamary, Gerard J, Criner
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Tiotropium Bromide/Olodaterol Related Acute Cognitive Impairments
Case Reports in Clinical Medicine, 2023exaly