Results 71 to 80 of about 3,023 (195)

Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype [PDF]

European Respiratory Journal, 2008
To the Editor: Although currently available asthma medications are very effective in the majority of cases, there remains a subgroup for which disease control is difficult. Anticholinergics have long been used to treat asthma, although their current role in therapy is supplementary 1.
H, Iwamoto, A, Yokoyama, N, Shiota, H, Shoda, Y, Haruta, N, Hattori, N, Kohno   +6 more
openaire   +2 more sources

Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024)

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Aim Chronic Obstructive Pulmonary Disease (COPD) is a common chronic airway disease that can lead to decreased lung function in patients. It places a heavy economic burden on patients and society. Traditional Chinese medicine (TCM) and Western medicine have played important roles in managing COPD.
Di Wu, Wei Liu, Jianxin Wang, Wei Chen, Mengyao Shi, Lu Zhang, Hui Wang, Huanzhang Ding, Xiao Ma, Yating Gao, Zengtao Sun, Jiangtao Lin, Hongchun Zhang, Suyun Li, Zhuying Li, Zhenhui Lu, Fuqiang Wen, Zegeng Li   +17 more
wiley   +1 more source

Dose of Inhaled Corticosteroid in Chronic Obstructive Pulmonary Disease and Risks of Osteoporosis or Fracture—A Systematic Review and Meta‐Analysis

The Clinical Respiratory Journal, Volume 19, Issue 5, May 2025.
High‐dose, but not medium‐ and low‐dose, ICS use in COPD is associated with risks of osteoporosis or fractures. ABSTRACT Background Inhaled corticosteroid (ICS) is a major pharmacotherapy for chronic obstructive pulmonary disease (COPD), which is associated with various adverse effects.
Wang Chun Kwok, Chung Ki Tsui, Sze Him Isaac Leung, Shuk Man Ngai, David Chi Leung Lam, Mary Sau Man Ip, James Chung Man Ho   +6 more
wiley   +1 more source

What is the influence of exacerbations on pulmonary function in pediatric and adolescent patients with severe asthma despite controller therapies?

Clinical and Translational Allergy, Volume 15, Issue 4, April 2025.
Abstract Background Although exacerbations are common in severe asthma, there have been few longitudinal studies evaluating their effect on lung function parameters. This study aimed to evaluate the impact of exacerbations on lung function in children and adolescents with severe asthma in Brazil.
A. Z. P. Brandão, L. M. L. B. F. Lasmar, L. M. A. S. Pertence, M. I. R. Vieira, G. B. Lasmar, V. O. Ganem, E. V. Mancuzo, M. V. N. P. de Queiroz   +7 more
wiley   +1 more source

Quantitative Analysis of Muscarinic Antagonist Atropine and Tiotropium in Microvolume Plasma Using Liquid Chromatography–Mass Spectrometry: Application for Pharmacokinetic Studies

Journal of Analytical Methods in Chemistry, Volume 2025, Issue 1, 2025.
Despite the availability of current resources, the development of medical countermeasures remains crucial in combatting the threat posed by chemical warfare agents, such as organophosphorus compounds (OPs), which are toxic nerve agents requiring rapid medical intervention.
Marilène Trancart, Mylène Penot, Gwladys Meesemaecker, Romain Boffy, Anne-Sophie Hanak, André-Guilhem Calas, Nicolas Taudon, Alessandro Buccolieri   +7 more
wiley   +1 more source

Cost-effectiveness of tiotropium versus omalizumab for uncontrolled allergic asthma in US

Cost Effectiveness and Resource Allocation, 2018
Background A significant minority of asthma patients remain uncontrolled despite the use of inhaled corticosteroids (ICS) and long-acting beta-agonists (LABA).
Zafar Zafari, Mohsen Sadatsafavi, J. Mark FitzGerald, for the Canadian Respiratory Research Network   +3 more
doaj   +1 more source

The Real‐World Analysis of Adverse Events With Two Types of Single‐Inhaler Triple Therapy: A VigiAccess Database Study

Journal of Clinical Pharmacy and Therapeutics, Volume 2025, Issue 1, 2025.
Background The advent of single‐inhaler triple therapies (SITTs), including fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) and beclomethasone dipropionate/formoterol fumarate/glycopyrronium bromide (BDP/FOR/GLY), has expanded treatment options for chronic obstructive pulmonary disease (COPD).
Baiquan Zhang, Jiayu Bai, Lu Zhou, Hongda Liu   +3 more
wiley   +1 more source

Safety and efficacy of formoterol/tiotropium bromide and formoterol/glycopyrronium combination in patients with chronic obstructive pulmonary disease

, 2023
Background: Chronic obstructive pulmonary disease is characterized by a progressive development of airflow limitation that is not fully reversible.
Ahmad, Zuber, Ahmad, Siraj, Ahmad, Farida, Ahmad, Jameel   +3 more
core   +1 more source

Drugs Used in the Treatment of Viral Infections for the Prevention of Airway Remodeling in Asthma

Mediators of Inflammation, Volume 2025, Issue 1, 2025.
One of the main causes of the exacerbation of chronic airway inflammatory diseases is respiratory virus infections. The most prevalent viruses that can infect humans multiple times a year are rhinovirus (RV) and respiratory syncytial virus (RSV). Because remodeling factors like matrix metalloproteinases (MMPs), which are released by infiltrating ...
Joanna Wieczfinska, Rafal Pawliczak, Mirella Giovarelli   +2 more
wiley   +1 more source

Efficacy and Safety of Aclidinium Bromide Compared with Placebo and Tiotropium in Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease: Results from a 6-week, Randomized, Controlled Phase Iiib Study

COPD, 2013
Background: This randomized, double-blind, Phase IIIb study evaluated the 24-hour bronchodilatory efficacy of aclidinium bromide versus placebo and tiotropium in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD).
Jutta Beier, Anne-Marie Kirsten, Robert Mróz, Rosa Segarra, Ferran Chuecos, Cynthia Caracta, Esther Garcia Gil   +6 more
doaj   +1 more source